Research output per year
Research output per year
Personal profile
Biography
Katherine's research is focused on understanding the basic mechanisms driving the neurodegenerative disease, Machado Joseph Disease (MJD). Katherine is particularly interested in how neural circuits within the brain may be disrupted in neurodegenerative diseases and aims to identify novel drug treatments that may slow or halt the progression of movement disorders.
Research interests
- Understanding the role of cerebellar circuit dysfunction in the pathogenesis of Machado Joseph Disease/Spinocerebellar Ataxia-3.
- Repeat non-AUG translation and pathogenic consequences of repeat expansions.
- The role of glutamate-induced excitotoxicity and proteolytic cleavage in neurodegeneration.
- Identifying novel candidates for the treatment of neurodegenerative diseases.
Fingerprint
Dive into the research topics where Katherine Jane Robinson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
A novel calpain inhibitor compound has protective effects on a zebrafish model of spinocerebellar ataxia type 3
Robinson, K. J., Yuan, K., Plenderleith, S. K., Watchon, M. & Laird, A., 29 Sep 2021, In: Cells. 10, 10, p. 1-15 15 p., 2592.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Flow cytometry allows rapid detection of protein aggregates in cell culture and zebrafish models of spinocerebellar ataxia-3
Robinson, K. J., Tym, M. C., Hogan, A., Watchon, M., Yuan, K. C., Plenderleith, S. K., Don, E. K. & Laird, A. S., 10 Mar 2021, (Submitted) In: bioRxiv.Research output: Contribution to journal › Article
File11 Downloads (Pure) -
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3
Robinson, K. J., Tym, M. C., Hogan, A., Watchon, M., Yuan, K. C., Plenderleith, S. K., Don, E. K. & Laird, A. S., 1 Oct 2021, In: DMM Disease Models and Mechanisms. 14, 10, p. 1-12 12 p., dmm049023.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo
Watchon, M., Luu, L., Robinson, K. J., Yuan, K. C., De Luca, A., Suddull, H. J., Tym, M. C., Guillemin, G. J., Cole, N. J., Nicholson, G. A., Chung, R. S., Lee, A. & Laird, A. S., 20 Aug 2021, In: Molecular Brain. 14, 1, p. 1-16 16 p., 128.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Aberrant cerebellar circuitry in the spinocerebellar ataxias
Robinson, K. J., Watchon, M. & Laird, A. S., 16 Jul 2020, In: Frontiers in Neuroscience. 14, p. 1-27 27 p., 707.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Citations (Scopus)17 Downloads (Pure)