• Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
20172021

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Personal profile

Biography

Katherine's research is focused on understanding the basic mechanisms driving the neurodegenerative disease, Machado Joseph Disease (MJD). Katherine is particularly interested in how neural circuits within the brain may be disrupted in neurodegenerative diseases and aims to identify novel drug treatments that may slow or halt the progression of movement disorders. 

Research interests

  • Understanding the role of cerebellar circuit dysfunction in the pathogenesis of Machado Joseph Disease/Spinocerebellar Ataxia-3. 
  • Repeat non-AUG translation and pathogenic consequences of repeat expansions.
  • The role of glutamate-induced excitotoxicity and proteolytic cleavage in neurodegeneration. 
  • Identifying novel candidates for the treatment of neurodegenerative diseases. 

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