Research output per year
Research output per year
Personal profile
Biography
Katherine's research is focused on understanding the basic mechanisms driving the neurodegenerative disease, Machado Joseph Disease (MJD). Katherine is particularly interested how calpain proteases may contribute to the formation of pathological protein aggregates and aims to identify novel drug treatments that may slow or halt the neurodegenerative process.
Research interests
- Understanding the role of cerebellar circuit dysfunction in the pathogenesis of Machado Joseph Disease/Spinocerebellar Ataxia-3.
- The role of glutamate-induced excitotoxicity and proteolytic cleavage in neurodegeneration.
- Overlapping pathogenic mechanisms or pathologies across neurodegenerative diseases with differing underlying genetic causes.
- Identifying novel candidates for the treatment of neurodegenerative diseases.
Fingerprint
Dive into the research topics where Katherine Jane Robinson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Spermidine treatment: induction of autophagy but also apoptosis?
Watchon, M., Wright, A. L., Ahel, H. I., Robinson, K. J., Plenderleith, S. K., Kuriakose, A., Yuan, K. C. & Laird, A. S., 5 Mar 2024, In: Molecular Brain. 17, 1, p. 1-15 15 p., 15.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Downloads (Pure) -
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3
Watchon, M., Robinson, K. J., Luu, L., An, Y., Yuan, K. C., Plenderleith, S. K., Cheng, F., Don, E. K., Nicholson, G. A., Lee, A. & Laird, A. S., 31 Jan 2024, In: FASEB Journal. 38, 2, p. 1-19 19 p., e23429.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)73 Downloads (Pure) -
Machado Joseph disease severity is linked with gut microbiota alterations in transgenic mice
Gamage, H. K. A. H., Robinson, K. J., Luu, L., Paulsen, I. T. & Laird, A. S., Apr 2023, In: Neurobiology of Disease. 179, p. 1-13 13 p., 106051.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)89 Downloads (Pure) -
Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3
Watchon, M., Robinson, K. J., Luu, L., An, Y., Yuan, K. C., Plenderleith, S. K., Cheng, F., Don, E. K., Nicholson, G. A., Lee, A. & Laird, A. S., 12 Dec 2023, (Submitted) (bioRxiv).Research output: Working paper › Preprint
-
Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats
Baracz, S. J., Robinson, K. J., Wright, A. L., Turner, A. J., McGregor, I. S., Cornish, J. L. & Everett, N., Jul 2022, In: Neuropsychopharmacology. 47, 8, p. 1561–1573 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)69 Downloads (Pure)