Projects per year
Personal profile
Biography
Hon. Associate Professor Kathryn Goozee is the sole Director of the Kara Institute of Neurological Diseases Pty Ltd (KaRa MINDS), founded in 2015. Kathryn has more than 30 years’ experience in acute health and aged care services, holding senior positions including Director of Nursing, Clinical Nurse Consultant, Nurse Practitioner, and Director of Research. Kathryn completed her PhD in Neuroscience at the University of Western Australia in 2022, with a focus on Alzheimer’s disease prevention. As part of this work, she established and recruited 105 older people at risk of Alzheimer’s disease into a new cohort, the Kerr Anglican Retirement Village Initiative in Ageing Health (KARVIAH). Her research investigated the influence of oral curcumin in a double-blind, placebo-controlled study using blood biomarkers, cognition, and MRI/PET imaging, aligning her work with Macquarie University.
At KaRa MINDS, Kathryn leads a team of 18 staff conducting pharmacological studies for the prevention and treatment of dementia. KaRa MINDS is an official screening site for Alzheimer’s dementia Network (ADNeT) and has earned a strong reputation for recruitment and retention in clinical trials, patient safety, and high-quality data capture. Over the past decade, KaRa MINDS has conducted more than 50 clinical trials in dementia, including studies involving the recently TGA-approved monoclonal antibody therapies Leqembi™ and Kisunla™. These treatments are now accessible privately at KaRa MINDS.
Within the Dementia Research Centre at Macquarie University, led by Professor Lars Ittner, Kathryn is an invited member of the Leadership Group. She is also a Non-Executive Board Member of Scalabrini Communities Ltd and an Executive Member and Co-Chair of the Dementia Trials Australia (DTAus) network.
Research interests
Kathryn has a particular interest in research translation and in delivering scientific discovery to the bedside. Connecting the community with emerging research and enabling people with dementia and those at risk to access research are key areas of focus. The work at KaRa MINDS has expanded community access to emerging treatments that are often more than 10 years away from routine clinical practice. Other areas of research interest include:
- Dementia prevention / early detection
- Models of clinical practice
- Clinical trial pathways
- Patient and carer support
Education/Academic qualification
Alzheimers Disease, PhD, Preclinical blood biomarkers in Alzheimer’s disease and prevention using curcumin, University of Western Australia
Award Date: 29 Jul 2022
External positions
Non-Exec Board Director, Scalabrini Village Ltd
3 May 2024 → …
CEO/Director, KaRa Institute of Neurological Diseases
1 Feb 2015 → …
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Collaborations and top research areas from the last five years
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DEV 24: A novel protein-protein interaction inhibitor to treat Alzheimer’s disease
Ittner, L. (Primary Chief Investigator), Meier, R. (Chief Investigator), Van Eersel, J. (Chief Investigator), Tietz, O. (Chief Investigator), Ariawan, D. (Chief Investigator), Bi, M. (Chief Investigator) & Goozee, K. (Associate Investigator)
1/01/25 → 31/12/27
Project: Research
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Effect of CocoMCT on Clinical Factors related to Health, Cognition, Quality of Life and Alzheimer's disease-related Biomarkers EPS
Martins, R. (Primary Chief Investigator), Chatterjee, P. (Chief Investigator), Sohrabi, H. (Chief Investigator), Bacsi, A. (Chief Investigator) & Goozee, K. (Associate Investigator)
1/12/17 → …
Project: Research
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Investigating the diagnostic utility of hyperspectral retinal imaging in preclinical Alzheimer's disease
Martins, R. (Primary Chief Investigator), Gillatt, D. (Chief Investigator), Graham, S. L. (Chief Investigator), Chatterjee, P. (Associate Investigator), Goozee, K. (Associate Investigator), Gupta, S. (Associate Investigator), Shah, T. (Associate Investigator) & Sohrabi, H. (Associate Investigator)
1/12/17 → 13/10/20
Project: Research
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Plasma soluble TREM2 is associated with plasma pTau-181 and pTau-231 in cognitively normal older adults at risk of Alzheimer's disease
Asih, P. R., Morris, C. W., Wang, H., Pedrini, S., Goozee, K., Laws, S. M., Chatterjee, P., Taddei, K., Sohrabi, H. R., Rainey-Smith, S. R., Lim, C. K., Guillemin, G. J., Karikari, T. K., Masters, C. L., Zetterberg, H., Blennow, K., Ashton, N. J. & Martins, R. N., Jan 2026, In: Journal of Alzheimer's Disease. 109, 2, p. 832-844 13 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
The effects of different acetylcholinesterase inhibitors on EEG patterns in patients with Alzheimer’s disease: a systematic review
Arjmandi-Rad, S., Vestergaard Nieland, J. D., Goozee, K. G. & Vaseghi, S., Feb 2024, In: Neurological Sciences. 45, 2, p. 417-430 14 p.Research output: Contribution to journal › Review article › peer-review
24 Link opens in a new tab Citations (Scopus) -
Elevated plasma sclerostin is associated with high brain amyloid-β load in cognitively normal older adults
Yuan, J., Pedrini, S., Thota, R., Doecke, J., Chatterjee, P., Sohrabi, H. R., Teunissen, C. E., Verberk, I. M. W., Stoops, E., Vanderstichele, H., Meloni, B. P., Mitchell, C., Rainey-Smith, S., Goozee, K., Tai, A. C. P., Ashton, N., Zetterberg, H., Blennow, K., Gao, J. & Liu, D. & 4 others, , 4 Sept 2023, In: npj Aging. 9, 1, p. 1-8 8 p., 17.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Link opens in a new tab Citations (Scopus)99 Downloads (Pure) -
Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease
Chatterjee, P., Pedrini, S., Ashton, N. J., Tegg, M., Goozee, K., Singh, A. K., Karikari, T. K., Simrén, J., Vanmechelen, E., Armstrong, N. J., Hone, E., Asih, P. R., Taddei, K., Dore, V., Villemagne, V. L., Sohrabi, H. R., Zetterberg, H., Masters, C. L., Blennow, K. & Martins, R. N., Jun 2022, In: Alzheimer's and Dementia. 18, 6, p. 1141-1154 14 p.Research output: Contribution to journal › Article › peer-review
196 Link opens in a new tab Citations (Scopus) -
Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer’s disease
Chatterjee, P., Pedrini, S., Stoops, E., Goozee, K., Villemagne, V. L., Asih, P. R., Verberk, I. M. W., Dave, P., Taddei, K., Sohrabi, H. R., Zetterberg, H., Blennow, K., Teunissen, C. E., Vanderstichele, H. M. & Martins, R. N., 11 Jan 2021, In: Translational Psychiatry. 11, 1, p. 1-10 10 p., 27.Research output: Contribution to journal › Article › peer-review
Open AccessFile368 Link opens in a new tab Citations (Scopus)55 Downloads (Pure)