Research output per year
Research output per year
Personal profile
Biography
Dr Luan Luu is an early career post-doctoral research fellow in the Department of Biomedical Science, Macquarie University. He completed his PhD at The University of Melbourne where he studied the Amyloid Precursor Protein in Alzheimer’s Disease. Upon obtaining his PhD he moved to Macquarie University and joined Angela Lairds lab where he investigates potential therapeutics for Spinocerebellar Ataxia type 3.
Research interests
Dr Luan Luu focuses on therapeutics that enhances processes (macroautophagy) that degrade pathogenic misfolded proteins and organelles to restore cellular homeostasis. He has developed cellular models of Spinocerebellar Ataxia type 3 for screening potential therapeutics which can be trailed in animals of the disease. The compounds tested not only have a potential for the treatment of Spinocerebellar Ataxia type 3 but for other diseases that involve misfolded proteins, such as Huntington’s or other PolyQ disease.
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Research Outputs
- 384 Citations
- 2 h-Index
- 4 Article
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TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex
Rayner, S. L., Yang, S., Farrawell, N. E., Jagaraj, C. J., Cheng, F., Davidson, J. M., Luu, L., Redondo, A. G., Rábano, A., Borrego-Hernández, D., Atkin, J. D., Morsch, M., Blair, I. P., Yerbury, J. J., Chung, R. & Lee, A., 1 Jun 2022, In: Neurobiology of Disease. 167, p. 1-11 11 p., 105673.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo
Watchon, M., Luu, L., Robinson, K. J., Yuan, K. C., De Luca, A., Suddull, H. J., Tym, M. C., Guillemin, G. J., Cole, N. J., Nicholson, G. A., Chung, R. S., Lee, A. & Laird, A. S., 20 Aug 2021, In: Molecular Brain. 14, 1, p. 1-16 16 p., 128.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)2 Downloads (Pure) -
The Alzheimer's disease amyloid precursor protein and its neuritogenic actions
Luu, L., Ciccotosto, G. D. & Cappai, R., Sep 2021, In: Current Alzheimer Research. 18, 10, p. 772-786 15 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Amyloid precursor protein dimerisation reduces neurite outgrowth
Luu, L., Ciccotosto, G. D., Vella, L. J., Cheng, L., Roisman, L. C., Multhaup, G., Hill, A. F., Munter, L. M. & Cappai, R., 1 Jan 2019, In: Molecular Neurobiology. 56, 1, p. 13-28 16 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)
Activities
- 1 Participating in a conference, workshop or event series
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Faculty of Medicine and Health Sciences 2nd Annual EnCouRage Research Symposium
Dane Turner (Organiser), Angela Laird (Organiser), Emily Don (Organiser), Magdalena Lam (Organiser), Adam Keith Walker (Organiser), Marco Morsch (Organiser), Benjamin Heng (Organiser), Vanessa Tan (Organiser), Esther Lim (Organiser), Marina Junqueira Santiago (Organiser), Hami Shahheydari (Organiser), Luan Luu (Organiser) & Mark Butlin (Poster judge)
27 Oct 2017Activity: Participating in or organising an event › Participating in a conference, workshop or event series