Mariana Brocardo

Dr

  • 466 Citations
  • 14 h-Index
19952016
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Research Outputs 1995 2016

  • 466 Citations
  • 14 h-Index
  • 17 Article
  • 2 Chapter
  • 2 Meeting abstract
  • 2 Review article
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Article
1995

Co‐operative effect between insulin‐like growth factor‐1 and interleukin‐2 on DNA synthesis and interleukin‐2 receptor‐α chain expression in human lymphocytes

SCHILLACI, ROXANA., BROCARDO, MARIANA. G. & ROLDAN, ALICIA., 1995, In : Immunology and Cell Biology. 73, 4, p. 340-345 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Interleukin-2 Receptor alpha Subunit
Somatomedins
Interleukin-2
Lymphocytes
Insulin-Like Growth Factor I
1998

Downregulation of insulin-like growth factor-1 receptor (IGF-1R) expression in human T lymphocyte activation

Schillaci, R., Brocardo, M. G., Galeano, A. & Roldán, A., 1 Feb 1998, In : Cellular Immunology. 183, 2, p. 157-161 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Somatomedin Receptors
Lymphocyte Activation
Down-Regulation
T-Lymphocytes
Insulin-Like Growth Factor I
2000

Development of monoclonal oligobodies and chemically synthesized oligobodies

Radrizzani, M., Brocardo, M. G., Solveyra, C. G., Bianchini, M., Reyes, G. B., Cafferata, E. G., Ortiz, G. V. & Santa-Coloma, T. A., 2000, In : Medicina. 60, SUPPL. 2, p. 55-60 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Oligonucleotides
Immunoprecipitation
Western Blotting
Immunohistochemistry
Proteins
2001

APC senses cell-cell contacts and moves to the nucleus upon their disruption

Brocardo, M. G., Bianchini, M., Radrizzani, M., Reyes, G. B., Dugour, A. V., Taminelli, G. L., Gonzalez Solveyra, C. & Santa-Coloma, T. A., 2001, In : Biochemical and Biophysical Research Communications. 284, 4, p. 982-986 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Tumor Suppressor Proteins
beta Catenin
Plating
Edetic Acid
Oligonucleotides

Early effects of insulin-like growth factor-1 in activated human T lymphocytes

Brocardo, M. G., Schillaci, R., Galeano, A., Radrizzani, M., White, V., González Guerrico, A., Santa-Coloma, T. A. & Roldán, A., 2001, In : Journal of Leukocyte Biology. 70, 2, p. 297-305 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Somatomedins
T-Lymphocytes
Interleukin-2
Phosphorylation
Somatomedin Receptors

Specific oligobodies against ERK-2 that recognize both the native and the denatured state of the protein

Bianchini, M., Radrizzani, M., Brocardo, M. G., Reyes, G. B., Gonzalez Solveyra, C. & Santa-Coloma, T. A., 1 Jun 2001, In : Journal of Immunological Methods. 252, 1-2, p. 191-197 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Oligonucleotides
Proteins
Immunoprecipitation
Western Blotting
Immunohistochemistry
2005

Redefining the subcellular location and transport of APC: New insights using a panel of antibodies

Brocardo, M., Näthke, I. S. & Henderson, B. R., 2005, In : EMBO Reports. 6, 2, p. 184-190 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Adenomatous Polyposis Coli
Fractionation
Tumors
Antibodies
Small Interfering RNA
2006

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: Targeting sequences and regulation by β-catenin

Sharma, M., Leung, L., Brocardo, M., Henderson, J., Flegg, C. & Henderson, B. R., 23 Jun 2006, In : Journal of Biological Chemistry. 281, 25, p. 17140-17149 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Adenomatous Polyposis Coli Protein
Cell Surface Extensions
beta Catenin
Membranes
Protein Transport
2008

Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: Regulation of Bcl-2 and implications for cell survival

Brocardo, M., Lei, Y., Tighe, A., Taylor, S. S., Mok, M. T. S. & Henderson, B. R., 29 Feb 2008, In : Journal of Biological Chemistry. 283, 9, p. 5950-5959 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Adenomatous Polyposis Coli Protein
Adenomatous Polyposis Coli
Mitochondria
Tumors
Cell Survival
2010

Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56α: Role of B56α in nuclear export of the catalytic subunit

Flegg, C. P., Sharma, M., Medina-Palazon, C., Jamieson, C., Galea, M., Brocardo, M. G., Mills, K. & Henderson, B. R., 11 Jun 2010, In : Journal of Biological Chemistry. 285, 24, p. 18144-18154 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Protein Phosphatase 2
Centrosome
Cell Nucleus Active Transport
Catalytic Domain
Protein Isoforms
2011

Adenomatous polyposis coli protein regulates the cellular response to DNA replication stress

Brocardo, M. G., Borowiec, J. A. & Henderson, B. R., Sep 2011, In : International Journal of Biochemistry and Cell Biology. 43, 9, p. 1354-1364 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Adenomatous Polyposis Coli Protein
Replication Protein A
Adenomatous Polyposis Coli
DNA Replication
DNA

IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest

Johnson, M., Sharma, M., Brocardo, M. G. & Henderson, B. R., Jan 2011, In : International Journal of Biochemistry and Cell Biology. 43, 1, p. 65-73 9 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA Replication
S Phase
Cell Cycle
Cells
DNA
2014

Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy

Martino-Echarri, E., Henderson, B. R. & Brocardo, M. G., 2014, In : Oncotarget. 5, 20, p. 9889-9900 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Adenomatous Polyposis Coli
DNA Replication
Fluorouracil
Colonic Neoplasms
Drug Therapy
2015

Rac1 augments Wnt signaling by stimulating β-catenin-lymphoid enhancer factor-1 complex assembly independent of β-catenin nuclear import

Jamieson, C., Lui, C., Brocardo, M. G., Martino-Echarri, E. & Henderson, B. R., 1 Nov 2015, In : Journal of Cell Science. 128, 21, p. 3933-3946 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
TCF Transcription Factors
Cell Nucleus Active Transport
beta Catenin
Transcriptional Activation
Ligation
2016

APC binds the miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane

Mills, K. M., Brocardo, M. G. & Henderson, B. R., 1 Feb 2016, In : Molecular Biology of the Cell. 27, 3, p. 466-482 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Adenomatous Polyposis Coli
Mitochondria
Cell Membrane
Mutation
Kinesin

APC functions at the centrosome to stimulate microtubule growth

Lui, C., Ashton, C., Sharma, M., Brocardo, M. G. & Henderson, B. R., 1 Jan 2016, In : International Journal of Biochemistry and Cell Biology. 70, p. 39-47 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Centrosome
Adenomatous Polyposis Coli
Tubulin
Microtubules
Nucleation

Tankyrase inhibitors stimulate the ability of tankyrases to bind axin and drive assembly of β-catenin degradation-competent axin puncta

Martino-Echarri, E., Brocardo, M. G., Mills, K. M. & Henderson, B. R., 1 Mar 2016, In : PLoS ONE. 11, 3, p. 1-19 19 p., e0150484.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Tankyrases
beta Catenin
colorectal neoplasms
Degradation
degradation