• 86 Citations
  • 3 h-Index
20132017
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

After some years working as a community pharmacist, I came to Macquarie University to do a PhD in Pharmacology. I finished my PhD in 2015, where I researched the effect of single nucleotide polymorphisms and phosphomutation of the mu-opioid receptor.

After concluding my PhD, I started working for Prof. Mark Connor and the Lambert Initiative for Cannabinoid Therapeutics. The project focus in the creation of platforms for the cell based elucidation of potential cannabinoid mechanisms of action in epilepsies.

Now I am engaged in teaching pharmacology, research and professional practice, in addition to continue researching molecular pharmacology of cannabinoids and opioids.

External positions

Liaison Pharmacist , Drugs and Alcohol Services - Nepean Blue Mountains Local Health District

Jul 2016Jan 2017

Community Pharmacist, Dee Why Grand Pharmacy

May 2011Jun 2016

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 7 Similar Profiles
mu Opioid Receptor Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
Buprenorphine Medicine & Life Sciences
Cannabinoids Medicine & Life Sciences
Ligands Medicine & Life Sciences
Morphine Medicine & Life Sciences
G-Protein-Coupled Receptors Chemical Compounds
Assays Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2013 2017

  • 86 Citations
  • 3 h-Index
  • 5 Article

Development of bright and biocompatible nanoruby and its application to background-free time-gated imaging of G-protein-coupled receptors

Sreenivasan, V. K. A., Wan Razali, W. A., Zhang, K., Pillai, R. R., Saini, A., Denkova, D., Santiago, M., Brown, H., Thompson, J., Connor, M., Goldys, E. M. & Zvyagin, A. V., 15 Nov 2017, In : ACS Applied Materials and Interfaces. 9, 45, p. 39197-39208 12 p.

Research output: Contribution to journalArticleResearchpeer-review

G-Protein-Coupled Receptors
Proteins
Imaging techniques
mu Opioid Receptor
Cytotoxicity

Pharmacology of valinate and tert-leucinate synthetic cannabinoids 5f-ambica, 5f-amb, 5f-adb, amb-fubinaca, mdmb-fubinaca, mdmb-chmica, and their analogues

Banister, S. D., Longworth, M., Kevin, R., Sachdev, S., Santiago, M., Stuart, J., Mack, J. B. C., Glass, M., McGregor, I. S., Connor, M. & Kassiou, M., 21 Sep 2016, In : ACS Chemical Neuroscience. 7, 9, p. 1241-1254 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Cannabinoids
Pharmacology
Hypothermia
Biotelemetry
Indazoles

A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro

Knapman, A., Santiago, M. & Connor, M., 5 Jan 2015, In : British Journal of Pharmacology. 172, 9, p. 2258-2272 15 p.

Research output: Contribution to journalArticleResearchpeer-review

mu Opioid Receptor
Morphine
Opioid Analgesics
Buprenorphine
CHO Cells

Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro

Knapman, A., Santiago, M. & Connor, M., 2014, In : British Journal of Pharmacology. 171, 18, p. 4273-4288 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Buprenorphine
mu Opioid Receptor
Opioid Analgesics
Ligands
CHO Cells

A continuous, fluorescence-based assay of μ-opioid receptor activation in AtT-20 cells

Knapman, A., Santiago, M., Du, Y. P., Bennallack, P. R., Christie, M. J. & Connor, M., Mar 2013, In : Journal of Biomolecular Screening. 18, 3, p. 269-276 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
mu Opioid Receptor
Opioid Analgesics
Assays
Fluorescence
Chemical activation

Activities 2015 2017

  • 2 Publication Peer-review
  • 1 Oral presentation

PeerJ (Journal)

Marina Santiago (Reviewer)
2017

Activity: Publication peer-review and editorial workPublication Peer-review

Signalling modification by Single Nucleotide Polymorphisms in the third intracellular loop of the mu-opioid receptor

Marina Junqueira Santiago (Speaker)
8 Dec 2017

Activity: Talk or presentationOral presentation

British Journal of Pharmacology (Journal)

Marina Junqueira Santiago (Reviewer)
2015

Activity: Publication peer-review and editorial workPublication Peer-review