Projects per year
Personal profile
Biography
I am Pharmacologist interested in psychoactive drugs, particularly cannabinoids, opioids and psychedelics. My lab studies how these molecules interact with G protein coupled receptors and ion channels to exert their effects. Currently my work is focussed on the pharmacology and toxicity of emerging synthetic cannabinoid receptor agonists (Spice/K2), the molecular mechanisms underlying the potential therapeutic actions of phytocannabinoids, the pharmacology of novel psychedelics and the interactions of clinically used opioids naturally occuring variants of opioid receptors.
Education/Academic qualification
Pharmacology, PhD, Identification of endogenous ligands for the haloperidol-sensitive sigma receptor in rat brain, University of Washington (UW)
Award Date: 18 Dec 1992
Pharmacology, Genetics, BSc (Hons), An investigation of the neurotoxicity of textilotoxin and its subunits, University of Sydney
Award Date: 25 May 1988
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Collaborations and top research areas from the last five years
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FAAB: ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB)
Rodger, A., Sunna, A., Garcia-Bennett, A., Guillemin, G., Packer, N., Thaysen-Andersen, M., Cain, A., Connor, M., Haynes, P., Paulsen, I., Ponton, F., Tetu, S., Wang, Y., Adcock, J., Callahan, D., Walsh, T. R., Joyce, P., Prestidge, C. A., Reddy, N., Ashton, J., Ball, M., Bucca, D., de Silva, T., Ferguson, K., Gilbert, A., Gilbert, E., Hayes, E., Mazumder, D., Morrison, J., Petrie, J., Pollard, N., Ruff, N., Stockham, K., Winberg, P. & De Simone, A.
21/02/22 → 20/02/27
Project: Research
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Development of next-generation targeted therapies for epilepsy and pain based on cannabinoid derivatives
Bladen, C. & Connor, M.
3/07/17 → …
Project: Research
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Advanced protein quantification capability
Walker, A. K., Lee, A., Connor, M., Atkin, J., Lim, E., Baker, M. S., Rizos, H., Phillips, J. K., Yang, S. & Blair, I.
1/01/17 → …
Project: Research
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The pharmacology and toxicity of synthetic cannabinoids
Connor, M., Kassiou, M. & McGregor, I.
1/01/16 → …
Project: Research
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Activation of CB2 Receptors by (−)-Cannabichromene but Not (+)-Cannabichromene
Udoh, M., Santiago, M., Haneef, S., Rodger, A., Marlowe, C. K., Barr, P. J. & Connor, M., 13 Aug 2024, (E-pub ahead of print) In: Cannabis and Cannabinoid Research. 8 p.Research output: Contribution to journal › Article › peer-review
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Single nucleotide polymorphisms in the cannabinoid CB2 receptor: molecular pharmacology and disease associations
Foyzun, T., Whiting, M., Velasco, K. K., Jacobsen, J. C., Connor, M. & Grimsey, N. L., Aug 2024, In: British Journal of Pharmacology. 181, 15, p. 2391-2412 22 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders
Kisely, S., Connor, M., Somogyi, A. A. & Siskind, D., Mar 2023, In: Australian & New Zealand Journal of Psychiatry. 57, 3, p. 362-378 17 p.Research output: Contribution to journal › Review article › peer-review
15 Citations (Scopus) -
Synthesis and preclinical evaluation of fluorinated 5-azaindoles as CB2 PET radioligands
Kallinen, A., Mardon, K., Lane, S., Montgomery, A. P., Bhalla, R., Stimson, D. H. R., Ahamed, M., Cowin, G. J., Hibbs, D., Werry, E. L., Fulton, R., Connor, M. & Kassiou, M., 16 Aug 2023, In: ACS Chemical Neuroscience. 14, 16, p. 2902-2921 20 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Defining steric requirements at CB1 and CB2 cannabinoid receptors using synthetic cannabinoid receptor agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1, PX-2, NNL-1, and their analogues
Markham, J., Sparkes, E., Boyd, R., Chen, S., Manning, J., Finlay, D., Lai, F., McGregor, E., Maloney, C. J., Gerona, R. R., Connor, M., McGregor, I. S., Hibbs, D. E., Glass, M., Kevin, R. C. & Banister, S. D., 20 Apr 2022, In: ACS Chemical Neuroscience. 13, 8, p. 1281-1295 15 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)
Datasets
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AtT-20 cell line expression data
Junqueira Santiago, M. (Contributor) & Connor, M. (Owner), Macquarie University, 10 Nov 2022
DOI: 10.25949/21529404.v1
Dataset