Mark Connor

Professor

  • 4692 Citations
  • 39 h-Index
1991 …2019
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Personal profile

Biography

I am Pharmacologist interested in analgesics and other psychoactive drugs, particularly cannabinoids and opioids. My lab studies how opioids, cannabinoids and related molecules interact with G protein coupled receptors and ion channels to exert their effects. Currently my work is focussed on how clinically used opioids interact with naturally occuring variants of human opioid receptors, the pharmacology and toxicity of emerging synthetic cannabinoid receptors agonists (Spice/K2) and the molecular mechanisms underlying the potential therapeutic actions of cannabis and its components.

Education/Academic qualification

Pharmacology, PhD, University of Washington

Pharmacology, Genetics, BSc (Hons), University of Sydney

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Projects 2008 2019

Research Outputs 1991 2019

Dark classics in Chemical Neuroscience: Δ 9 -tetrahydrocannabinol

Banister, S. D., Arnold, J. C., Connor, M., Glass, M. & Mcgregor, I. S., 15 May 2019, In : ACS Chemical Neuroscience. 10, 5, p. 2160-2175 16 p.

Research output: Contribution to journalReview articleResearchpeer-review

Dronabinol
Neurosciences
Cannabis
Medical Marijuana
Pharmacology

New-generation azaindole-adamantyl-derived synthetic cannabinoids

Longworth, M., Reekie, T. A., Blakey, K., Boyd, R., Connor, M. & Kassiou, M., 28 Feb 2019, In : Forensic Toxicology. 37, 2, p. 350-365 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cannabinoids
Ionization
Mass spectrometry
Assays
Mass Spectrometry

Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells

Heblinski, M., Bladen, C. & Connor, M., 1 Feb 2019, In : British Journal of Pharmacology. 176, 3, p. 451-465 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Receptor, Serotonin, 5-HT1B
Potassium Channels
Sumatriptan
Serotonin
G Protein-Coupled Inwardly-Rectifying Potassium Channels

Synthesis and in vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands

Kallinen, A., Boyd, R., Lane, S., Bhalla, R., Mardon, K., Stimson, D. H. R., Werry, E. L., Fulton, R., Connor, M. & Kassiou, M., 28 May 2019, In : Organic and Biomolecular Chemistry. 17, 20, p. 5086-5098 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Sulfones
sulfones
Fluorine
fluorine
Cannabinoid Receptor CB2

Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA

Banister, S. D., Adams, A., Kevin, R. C., Macdonald, C., Glass, M., Boyd, R., Connor, M., McGregor, I. S., Havel, C. M., Bright, S. J., Vilamala, M. V., Lladanosa, C. G., Barratt, M. J. & Gerona, R. R., Feb 2019, In : Drug Testing and Analysis. 11, 2, p. 279-291 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Artificial Receptors
Cannabinoid Receptor Agonists
Scaffolds
nuclear magnetic resonance
liquid chromatography