Projects per year
Personal profile
Biography
I am Pharmacologist interested in analgesics and other psychoactive drugs, particularly cannabinoids and opioids. My lab studies how opioids, cannabinoids and related molecules interact with G protein coupled receptors and ion channels to exert their effects. Currently my work is focussed on how clinically used opioids interact with naturally occuring variants of human opioid receptors, the pharmacology and toxicity of emerging synthetic cannabinoid receptors agonists (Spice/K2) and the molecular mechanisms underlying the potential therapeutic actions of cannabis and its components.
Education/Academic qualification
Pharmacology, PhD, University of Washington
Pharmacology, Genetics, BSc (Hons), University of Sydney
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2019
High-content screening platform
Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. & Laird, A.
1/01/19 → 31/12/19
Project: Research
Establishment of archival freezer storage bay
Chung, R., Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. & Laird, A.
1/01/19 → 31/12/19
Project: Research
Developing next-generation pain therapies based on Cannabinoid derivatives
15/05/18 → 15/05/19
Project: Research
Development of next-generation targeted therapies for epilepsy and pain based on cannabinoid derivatives
Bladen, C. & Connor, M.
3/07/17 → …
Project: Research
Advanced protein quantification capability
Walker, A., Lee, A., Connor, M., Atkin, J., Lim, C., Baker, M., Rizos, H., Phillips, J., Yang, S. & Blair, I.
1/01/17 → …
Project: Research
Research Output 1991 2019
New-generation azaindole-adamantyl-derived synthetic cannabinoids
Longworth, M., Reekie, T. A., Blakey, K., Boyd, R., Connor, M. & Kassiou, M., 28 Feb 2019, In : Forensic Toxicology.Research output: Contribution to journal › Article › Research › peer-review
Cannabinoids
Ionization
Mass spectrometry
Assays
Mass Spectrometry
Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells
Heblinski, M., Bladen, C. & Connor, M., 1 Feb 2019, In : British Journal of Pharmacology. 176, 3, p. 451-465 15 p.Research output: Contribution to journal › Article › Research › peer-review
Receptor, Serotonin, 5-HT1B
Potassium Channels
Sumatriptan
Serotonin
G Protein-Coupled Inwardly-Rectifying Potassium Channels
Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA
Banister, S. D., Adams, A., Kevin, R. C., Macdonald, C., Glass, M., Boyd, R., Connor, M., McGregor, I. S., Havel, C. M., Bright, S. J., Vilamala, M. V., Lladanosa, C. G., Barratt, M. J. & Gerona, R. R., Feb 2019, In : Drug Testing and Analysis. 11, 2, p. 279-291 13 p.Research output: Contribution to journal › Article › Research › peer-review
Artificial Receptors
Cannabinoid Receptor Agonists
Scaffolds
nuclear magnetic resonance
liquid chromatography
Conformationally rigid derivatives of WAY-267,464: synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors
Jorgensen, W. T., Gulliver, D. W., Katte, T. A., Werry, E. L., Reekie, T. A., Connor, M. & Kassiou, M., 1 Jan 2018, In : European Journal of Medicinal Chemistry. 143, p. 1644-1656 13 p.Research output: Contribution to journal › Article › Research › peer-review
Oxytocin Receptors
Vasopressin Receptors
Oxytocin
Vasopressins
Assays
The chemistry and pharmacology of synthetic cannabinoid receptor agonists as new psychoactive substances: origins
Banister, S. & Connor, M., 1 Jan 2018, New psychoactive substances: pharmacology, clinical, forensic and analytical toxicology. Maurer, H. H. & Brandt, S. D. (eds.). Switzerland, p. 165-190 26 p. (Handbook of Experimental Pharmacology; vol. 252).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
Artificial Receptors
Cannabinoid Receptor Agonists
Pharmacology
Cannabinoid Receptor CB1
Cannabinoid Receptor CB2