Projects per year
Personal profile
Biography
I am Pharmacologist interested in analgesics and other psychoactive drugs, particularly cannabinoids and opioids. My lab studies how opioids, cannabinoids and related molecules interact with G protein coupled receptors and ion channels to exert their effects. Currently my work is focussed on how clinically used opioids interact with naturally occuring variants of human opioid receptors, the pharmacology and toxicity of emerging synthetic cannabinoid receptors agonists (Spice/K2) and the molecular mechanisms underlying the potential therapeutic actions of cannabis and its components.
Education/Academic qualification
Pharmacology, PhD, University of Washington
Pharmacology, Genetics, BSc (Hons), University of Sydney
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Network
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Projects 2008 2019
Establishment of archival freezer storage bay
Chung, R., Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. & Laird, A.
1/01/19 → 31/12/19
Project: Research
High-content screening platform
Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. & Laird, A.
1/01/19 → 31/12/19
Project: Research
Developing next-generation pain therapies based on Cannabinoid derivatives
15/05/18 → 15/05/19
Project: Research
Development of next-generation targeted therapies for epilepsy and pain based on cannabinoid derivatives
Bladen, C. & Connor, M.
3/07/17 → …
Project: Research
Advanced protein quantification capability
Walker, A., Lee, A., Connor, M., Atkin, J., Lim, C., Baker, M., Rizos, H., Phillips, J., Yang, S. & Blair, I.
1/01/17 → …
Project: Research
Research Output 1991 2019
Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells
Heblinski, M., Bladen, C. & Connor, M., 1 Feb 2019, In : British Journal of Pharmacology. 176, 3, p. 451-465 15 p.Research output: Contribution to journal › Article › Research › peer-review
Receptor, Serotonin, 5-HT1B
Potassium Channels
Sumatriptan
Serotonin
G Protein-Coupled Inwardly-Rectifying Potassium Channels
Conformationally rigid derivatives of WAY-267,464: synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors
Jorgensen, W. T., Gulliver, D. W., Katte, T. A., Werry, E. L., Reekie, T. A., Connor, M. & Kassiou, M., 1 Jan 2018, In : European Journal of Medicinal Chemistry. 143, p. 1644-1656 13 p.Research output: Contribution to journal › Article › Research › peer-review
Oxytocin Receptors
Vasopressin Receptors
Oxytocin
Vasopressins
Assays
Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA
Banister, S. D., Adams, A., Kevin, R. C., Macdonald, C., Glass, M., Boyd, R., Connor, M., McGregor, I. S., Havel, C. M., Bright, S. J., Vilamala, M. V., Lladanosa, C. G., Barratt, M. J. & Gerona, R. R., 27 Aug 2018, In : Drug Testing and Analysis.Research output: Contribution to journal › Article › Research › peer-review
Artificial Receptors
Cannabinoid Receptor Agonists
Scaffolds
nuclear magnetic resonance
liquid chromatography
The chemistry and pharmacology of synthetic cannabinoid SDB-006 and its regioisomeric fluorinated and methoxylated analogs
Banister, S. D., Olson, A., Winchester, M., Stuart, J., Edington, A. R., Kevin, R. C., Longworth, M., Herrera, M., Connor, M., Mcgregor, I. S., Gerona, R. R. & Kassiou, M., Jul 2018, In : Drug Testing and Analysis. 10, 7, p. 1099-1109 11 p.Research output: Contribution to journal › Article › Research › peer-review
Cannabinoids
fluorine
Fluorine
biotelemetry
Pharmacology
The potentiating effect of calcitonin gene-related peptide on transient receptor potential vanilloid-1 activity and the electrophysiological responses of rat trigeminal neurons to nociceptive stimuli
Chatchaisak, D., Connor, M., Srikiatkhachorn, A. & Chetsawang, B., May 2018, In : Journal of Physiological Sciences. 68, 3, p. 261–268 8 p.Research output: Contribution to journal › Article › Research › peer-review
Nociceptors
Calcitonin Gene-Related Peptide
Trigeminal Ganglion
Organ Culture Techniques
Capsaicin