Projects per year
Personal profile
Biography
I am Pharmacologist interested in analgesics and other psychoactive drugs, particularly cannabinoids and opioids. My lab studies how opioids, cannabinoids and related molecules interact with G protein coupled receptors and ion channels to exert their effects. Currently my work is focussed on how clinically used opioids interact with naturally occuring variants of human opioid receptors, the pharmacology and toxicity of emerging synthetic cannabinoid receptors agonists (Spice/K2) and the molecular mechanisms underlying the potential therapeutic actions of cannabis and its components.
Education/Academic qualification
Pharmacology, PhD, University of Washington
Pharmacology, Genetics, BSc (Hons), University of Sydney
Fingerprint Dive into the research topics where Mark Connor is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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mu Opioid Receptor
Medicine & Life Sciences
Opioid Analgesics
Medicine & Life Sciences
Cannabinoids
Chemical Compounds
Pharmacology
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Periaqueductal Gray
Medicine & Life Sciences
Cannabinoid Receptor CB2
Medicine & Life Sciences
Cannabinoid Receptor CB1
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2008 2019
Development of next-generation targeted therapies for epilepsy and pain based on cannabinoid derivatives
Bladen, C. & Connor, M.
3/07/17 → …
Project: Research
Advanced protein quantification capability
Walker, A., Lee, A., Connor, M., Atkin, J., Lim, C., Baker, M., Rizos, H., Phillips, J., Yang, S. & Blair, I.
1/01/17 → …
Project: Research
Mechanisms underlying the repellent effects of predator odours in rodents
Connor, M., McGregor, I., Crowther, M. & Banister, S.
1/01/16 → …
Project: Research
The pharmacology and toxicity of synthetic cannabinoids
Connor, M., Kassiou, M. & McGregor, I.
1/01/16 → …
Project: Research
Establishment of archival freezer storage bay
Chung, R., Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. & Laird, A.
1/01/19 → 31/12/19
Project: Research
Research Outputs 1991 2019
Absence of entourage: terpenoids commonly found in Cannabis sativa do not modulate the functional activity of Δ9-THC at human CB1 and CB2 receptors
Santiago, M., Sachdev, S., Arnold, J. C., McGregor, I. & Connor, M., 1 Sep 2019, In : Cannabis and Cannabinoid Research. 4, 3, p. 165-176 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Cannabinoid Receptors
Dronabinol
Terpenes
Cannabis
Potassium Channels
Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells
Sachdev, S., Boyd, R., Grimsey, N. L., Santiago, M. & Connor, M., 25 Sep 2019, In : PeerJ. 2019, 9, p. 1-15 15 p., e7733.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
brodifacoum
Cannabinoid Receptors
adenylate cyclase
HEK293 Cells
Adenylyl Cyclases
Cannabichromene is a Cannabinoid CB2 receptor agonist
Udoh, M., Santiago, M., Devenish, S., McGregor, I. & Connor, M., Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4537-4547 11 p.Research output: Contribution to journal › Article › Research › peer-review
Cannabinoid Receptor CB2
Cannabinoid Receptor Agonists
Cannabinoid Receptor CB1
Dronabinol
Cell Surface Receptors
Dark classics in Chemical Neuroscience: Δ 9 -tetrahydrocannabinol
Banister, S. D., Arnold, J. C., Connor, M., Glass, M. & Mcgregor, I. S., 15 May 2019, In : ACS Chemical Neuroscience. 10, 5, p. 2160-2175 16 p.Research output: Contribution to journal › Review article › Research › peer-review
Dronabinol
Neurosciences
Cannabis
Medical Marijuana
Pharmacology
In vitro determination of the efficacy of illicit synthetic cannabinoids at CB1 receptors
Sachdev, S., Vemuri, K., Banister, S. D., Longworth, M., Kassiou, M., Santiago, M., Makriyannis, A. & Connor, M., 14 Aug 2019, (Accepted/In press) In : British Journal of Pharmacology. 13 p.Research output: Contribution to journal › Article › Research › peer-review
Artificial Receptors
Cannabinoid Receptor Agonists
Cannabinoid Receptor CB1
Dronabinol
Somatostatin Receptors