Projects per year
Personal profile
Biography
Prof Martin Hoyle is a Professor of Health Innovation and Evaluation at the Macquarie University Centre for the Health Economy (MUCHE).
He now leads a team of researchers in MUCHE that work on submissions for the Australian Medical Services Advisory Committee (MSAC) and critique pharmaceutical company submissions to the Australian Pharmaceutical Benefits Advisory Committee (PBAC).
Prof Hoyle has evaluated drugs in many clinical areas including various cancers (chronic lymphocytic leukaemia, chronic myeloid leukaemia, multiple myeloma, neuroendocrine tumours, colorectal cancer, gastro-intestinal stromal tumours, renal cell carcinoma, soft tissue sarcoma), chemotherapy-induced anaemia, multiple sclerosis, Alzheimer's disease. Other evaluations include vaccines for influenza, cochlear implants for hearing, diagnostic tests for Lynch Syndrome, tests for pre-term labour in women, influenza vaccines. He has defended Assessment Group reports at 34 UK NICE Appraisal Committee meetings and 11 ESC meetings in Australia.
He has published papers on HTA methodology, specifically on assumptions regarding appropriate patient cohorts to model, assumptions for future drug prices and a method to recreate and analyse individual patient data using only summary survival data.
He was the external examiner for the MSc in Health Economics and Decision Modelling, University of Sheffield, from 2016 to 2018, and was a panel member for the Research for Patient Benefit (RfPB) South West. In 2017-8, he was also an advisor to NICE on implementation of the NICE Fast Track Appraisal (FTA) process, and an advisor to NICE on implementation of the "Adjusted TA" process.
Prior to joining the Centre, Martin was Director of PenTAG (Peninsula Technology Assessment Group) in the Medical School at the University of Exeter, where he performed health technology assessments for the National Institute for Health and Care Excellence (NICE), and the National Institute for Health Research (NIHR) in the United Kingdom. His undergraduate training was in Mathematics at the University of Cambridge. This accounts for his interest in the mathematics and statistics of HTA.
Education/Academic qualification
Ecology, PhD
1 Sept 2000 → 1 Dec 2003
Award Date: 1 Apr 2004
Ecology, MSc
31 Oct 1999 → 31 Aug 2001
Award Date: 1 Aug 2000
Mathematical Statistics, Diploma
30 Sept 1992 → 31 Jul 1993
Award Date: 1 Jul 1993
Mathematics, MA
1 Oct 1989 → 31 Jul 1992
Award Date: 1 Jul 1992
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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EXTERNAL EVALUATION OF PHARMACEUTICAL BENEFITS ADVISORY COMMITTEE (PBAC) AND HEALTH TECHNOLOGY RELATED SUBMISSIONS
Cutler, H., Hoyle, M., Parkinson, B., Jeet, V., Norman, A., Seil, E., Sharma, R., Song, R., Ahumada Canale, A., Mumford, V., Vagholkar, S., Pont, L. G., Amin, J., Gu, Y., Schroeder, L. & Soytemiz, A.
1/07/21 → 30/06/25
Project: Research
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Services for external evaluation of Pharmaceutical Benefits Advisory Committee (PBAC) and health technology related submissions
Cutler, H., Parkinson, B., McLeod, R., Dalziel, K., Mutowo, M., Mumford, V., Vagholkar, S., Pont, L. G., Song, R., Jeet, V., Hoyle, M., Seil, E., Norman, A., Partington, A. & Gu, Y.
1/11/16 → …
Project: Research
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MSAC: PICO Confirmation for HPP200250 - Liquid biopsy in patients with non-small cell lung carcinoma
Cutler, H., Hoyle, M. & Raichand, S.
28/01/25 → 12/06/25
Project: Research
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MSAC DCAR-1710 Newborn bloodspot screening for X-linked adrenoleukodystrophy
Cutler, H., Hoyle, M., Jeet, V., Seil, E., Stark, Z., Rana, R., Song, R., Parkinson, B. & Norman, A.
6/12/22 → 9/06/23
Project: Research
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MSAC PICO-1710 X-linked adrenoleukodystrophy (X-ALD) Newborn Bloodspot Screening
Cutler, H., Seil, E., Hoyle, M., Stark, Z. & Soytemiz, A.
9/05/22 → 31/08/22
Project: Research
File
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Unravelling the association between uncertainties in model-based economic analysis and funding recommendations of medicines in Australia
Chen, Q., Hoyle, M., Jeet, V., Gu, Y., Sinha, K. & Parkinson, B., Mar 2025, In: PharmacoEconomics. 43, 3, p. 283–296 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Bring out your dead: a review of the cost minimisation approach in health technology assessment submissions to the Australian pharmaceutical benefits advisory committee
Tirrell, Z., Norman, A., Hoyle, M., Lybrand, S. & Parkinson, B., Nov 2024, In: PharmacoEconomics. 42, 11, p. 1287-1300 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Downloads (Pure) -
Bring out your dead: A review of the cost minimization approach in health technology assessment submissions to the Australian Pharmaceutical Benefits Advisory Committee
Tirrell, Z., Norman, A., Hoyle, M., Lybrand, S. & Parkinson, B., Jun 2023, In: Value in Health. 26, 6, p. S260-S260 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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Economic evaluation of three BRAF + MEK inhibitors for the treatment of advanced unresectable melanoma with BRAF mutation from a US payer perspective
Halloush, S., Alkhatib, N. S., Almutairi, A. R., Calamia, M., Halawah, H., Obeng-Kusi, M., Hoyle, M., Rashdan, O., Koeller, J. & Abraham, I., Sept 2023, In: Annals of Pharmacotherapy. 57, 9, p. 1016-1024 9 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Histopathologically validated diagnostic accuracy of PSMA-PET/CT in the primary and secondary staging of prostate cancer and the impact of PSMA-PET/CT on clinical management: a systematic review and meta-analysis
Jeet, V., Parkinson, B., Song, R., Sharma, R. & Hoyle, M., Sept 2023, In: Seminars in Nuclear Medicine. 53, 5, p. 706-718 13 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus)
Datasets
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The use of the cost minimisation approach in Health Technology Assessment submissions to the Australian Pharmaceutical Benefits Advisory Committee
Tirrell, Z. (Owner), Lybrand, S. (Contributor), Norman, A. (Contributor), Hoyle, M. (Contributor) & Parkinson, B. (Contributor), Macquarie University, 1 Aug 2024
DOI: 10.25949/26308576.v1
Dataset
Prizes
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2011 ISPOR Award for Excellence in Methodology in Pharmacoeconomics and Health Outcomes Research
Hoyle, Martin (Recipient), 1 Jan 2011
Prize
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2019 Macquarie Business School Impact Competition, Improving health and spending money wisely: evaluating medicines and vaccines for the Australian Government
Cutler, Henry (Recipient), Parkinson, Bonny (Recipient) & Hoyle, Martin (Recipient), 1 Jan 2020
Prize
File -
2022 Macquarie Business School Impact Competition, Improving Health and Spending Money Wisely: Evaluating Medical Tests, Devices, Procedures for the Australian Government
Hoyle, Martin (Recipient), Cutler, Henry (Recipient), Parkinson, Bonny (Recipient), Norman, Alicia (Recipient), Jeet, Varinder (Recipient), Seil, Elizabeth (Recipient), Sharma, Rajan (Recipient), Song, Rachel (Recipient), Ahumada Canale, Antonio (Recipient), Rana, Rezwanul (Recipient), Mumford, Virginia (Recipient) & Amin, Janaki (Recipient), 2022
Prize
Activities
- 2 Other
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Recruitment 2020
Martin Hoyle (Participant), Henry Cutler (Participant) & Bonny Parkinson (Participant)
23 Oct 2020Activity: Other
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Recruitment 2019
Martin Hoyle (Participant), Henry Cutler (Participant) & Bonny Parkinson (Participant)
1 Aug 2019Activity: Other
Press/Media
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Machine Learning for Precision Medicine and Health Economics
Meimei Chen, Martin Hoyle, Yuanyuan Gu & Noemi Kreif
2/12/22
1 Media contribution
Press/Media: Research
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Submission into Senate Inquiry into Approval Processes for New Drug and Novel Medical Technologies in Australia. I took questions from Members of Parliament for 1/2 hour. Appearance at Members of the Standing Committee on Health.
Bonny Parkinson, Martin Hoyle & Henry Cutler
11/03/21
1 Media contribution
Press/Media: Public Engagement Activities
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Affect of wind patterns on dispersal of pollen from genetically modified crops. National Radio 4.
1/01/07
1 Media contribution
Press/Media: Expert Comment
Impacts
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Improving health and spending money wisely: evaluating medical tests, devices, procedures for the Australian Government
Martin Hoyle (Participant), Henry Cutler (Participant), Bonny Parkinson (Participant), Alicia Norman (Participant), Varinder Jeet (Participant), Elizabeth Seil (Participant), Rajan Sharma (Participant), Huaxia Song (Participant), Antonio Ahumada Canale (Participant), Rezwanul Rana (Participant), Virginia Mumford (Participant) & Janaki Amin (Participant)
Impact: Health impacts, Economy impacts, Policy impacts
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Improving health and spending money wisely: evaluating medicines and vaccines for the Australian Government
Henry Cutler (Participant), Bonny Parkinson (Participant), Martin Hoyle (Participant), Mutsa Mutowo (Participant), Huaxia Song (Participant), Andrew Partington (Participant), Varinder Jeet (Participant), Elizabeth Seil (Participant), Alicia Norman (Participant), Virginia Mumford (Participant), Sanjyot Vagholkar (Participant), Lisa Pont (Participant) & Janaki Amin (Participant)
Impact: Quality of life impacts, Economy impacts, Policy impacts