• 151 Citations
  • 9 h-Index
20032022
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Biological engineer with diverse research experience ranging from chlorophyll biosynthesis to designing and building synthetic virus genomes. Proven track record in scientific publications, mentoring and leadership.

Research interests

The Jaschke Lab bridges the fields of Synthetic Biology, Microbiology, Virology, and Systems Biology to answer fundamental questions of:

(1) how to discover all the components necessary to make a functional genome? 

(2) how to reconfigure these components to make engineered genomes more reliable and predictable?

(3) how to engineer biology to benefit human health and reduce impacts on our environment?

 

We aim to answer important questions by pioneering the science and engineering of synthetic genomes by designing, building, testing, and learning from our designs.

Fingerprint Dive into the research topics where Paul Jaschke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Rhodobacter sphaeroides Medicine & Life Sciences
Bacteriochlorophylls Medicine & Life Sciences
RNA, Transfer, Met Medicine & Life Sciences
Amber Medicine & Life Sciences
Zinc Medicine & Life Sciences
Terminator Codon Medicine & Life Sciences
Bacteriochlorophyll A Chemical Compounds
Escherichia coli Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2016 2022

Research Outputs 2003 2019

  • 151 Citations
  • 9 h-Index
  • 12 Article
  • 1 Meeting abstract
  • 1 Letter

An orthogonal amber initiator tRNA functions similarly across diverse Escherichia coli laboratory strains

Vincent, R., Yiasemides, P. & Jaschke, P., 1 May 2019, In : Matters.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
RNA, Transfer, Met
Amber
Terminator Codon
Initiator Codon
Escherichia coli

Measuring amber initiator tRNA orthogonality in a genomically recoded organism

Vincent, R. M., Wright, B. W. & Jaschke, P. R., 2019, In : ACS Synthetic Biology. 8, 4, p. 675-685 11 p.

Research output: Contribution to journalLetterResearchpeer-review

RNA, Transfer, Met
Amber
Terminator Codon
Proteins
Amino Acid-Specific Transfer RNA

Measurements of translation initiation from all 64 codons in E. coli

Hecht, A., Glasgow, J., Jaschke, P. R., Bawazer, L. A., Munson, M. S., Cochran, J. R., Endy, D. & Salit, M., 20 Apr 2017, In : Nucleic acids research. 45, 7, p. 3615-3626 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Codon
Initiator Codon
Escherichia coli
Green Fluorescent Proteins
Peptides

Wet Lab Accelerator: a web-based application democratizing laboratory automation for synthetic biology

Bates, M., Berliner, A. J., Lachoff, J., Jaschke, P. R. & Groban, E. S., 20 Jan 2017, In : ACS Synthetic Biology. 6, 1, p. 167-171 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Laboratory Automation
Synthetic Biology
Particle accelerators
Hope
Automation

A fully decompressed synthetic bacteriophage øX174 genome assembled and archived in yeast

Jaschke, P. R., Lieberman, E. K., Rodriguez, J., Sierra, A. & Endy, D., 20 Dec 2012, In : Virology. 434, 2, p. 278-284 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Bacteriophages
Yeasts
Genome
Nucleotides
Escherichia coli