• 174 Citations
  • 9 h-Index

Research output per year

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Personal profile


Biological engineer with diverse research experience ranging from chlorophyll biosynthesis to designing and building synthetic virus genomes. Proven track record in scientific publications, mentoring and leadership.

Research interests

The Jaschke Lab bridges the fields of Synthetic Biology, Microbiology, Virology, and Systems Biology to answer fundamental questions of:

(1) how to discover all the components necessary to make a functional genome? 

(2) how to reconfigure these components to make engineered genomes more reliable and predictable?

(3) how to engineer biology to benefit human health and reduce impacts on our environment?


We aim to answer important questions by pioneering the science and engineering of synthetic genomes by designing, building, testing, and learning from our designs.

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Developing a complete set of orthogonal tRNAs to expand translation control

Jaschke, P., Hutvagner, A. & Wilding, M.


Project: Other

Treatment of multi-drug resistant infections using a novel, rapid and customised synthetic phage therapy platform

Jaschke, P., Weynberg, K., Holowko, M., Barr, J. & Mimee, M.


Project: Other

Research Outputs

  • 174 Citations
  • 9 h-Index
  • 15 Article
  • 1 Meeting abstract
  • 1 Letter

Building better bacteriophage with biofoundries to combat antibiotic-resistant bacteria

Weynberg, K. D. & Jaschke, P. R., 25 Feb 2020, In : PHAGE: Therapy, Applications, and Research. 1, 1, p. 23-26 4 p.

Research output: Contribution to journalArticle

  • An orthogonal amber initiator tRNA functions similarly across diverse Escherichia coli laboratory strains

    Vincent, R., Yiasemides, P. & Jaschke, P., 1 May 2019, In : Matters. p. 1-11 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Downloads (Pure)

    Definitive demonstration by synthesis of genome annotation completeness

    Jaschke, P. R., Dotson, G. A., Hung, K. S., Liu, D. & Endy, D., 26 Nov 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24206-24213 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • 5 Downloads (Pure)

    Measuring amber initiator tRNA orthogonality in a genomically recoded organism

    Vincent, R. M., Wright, B. W. & Jaschke, P. R., 19 Apr 2019, In : ACS Synthetic Biology. 8, 4, p. 675-685 11 p.

    Research output: Contribution to journalLetter

  • 3 Citations (Scopus)