• 2137 Citations
  • 27 h-Index
1984 …2020
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Personal profile


Our research interests lie in the application of small molecules to biological systems, which involves new and exciting multidisciplinary approaches incorporating molecular biology, organic synthesis, analytical chemistry, NMR spectroscopy, computational chemistry and biochemistry to solving medicinally relevant problems. We are particularly interested in marine natural products and fluorescent natural products, their biological activity, biosynthesis and most importantly, their modes of action as drugs and applications in biotechnology.

External positions

CEO, Hyperdrive Science Pty Ltd

1 Mar 2018 → …

CSO, FLUOROtechnics Pty Ltd.

1 Jan 200431 Dec 2008

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  • 1 Similar Profiles
Biological Products Medicine & Life Sciences
Porifera Medicine & Life Sciences
Fluorescence Chemical Compounds
Metabolites Chemical Compounds
Coloring Agents Chemical Compounds
Proteins Chemical Compounds
Proteomics Medicine & Life Sciences
Fluorophores Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2006 2020

Reverse Chemical Proteomics: Harnessing Yeast Display for Drug Discovery

Piggott, A., Karuso, P., Kwon, H. J. & MQRES (International), M. (.


Project: Research

Acoustic liquid handling robotics for bioactive compound discovery

Karuso, P., Poulsen, S., Avery, V., Quinn, R., Jonathan, B., Scanlon, M., Cooper, M., Booker, G., Professor, S., Guillemin, G., Smith, J., Ryan, J. & Peat, T.

10/03/17 → …

Project: Research

Dual Emission Fluorophores

Karuso, P.


Project: Research

Research Outputs 1984 2020

Room-temperature dual fluorescence of a locked green fluorescent protein chromophore analogue

Chatterjee, S., Ahire, K. & Karuso, P., 15 Jan 2020, In : Journal of the American Chemical Society. 142, 2, p. 738-749 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Green Fluorescent Proteins

Bisindole alkaloids from a New Zealand deep-sea marine sponge Lamellomorpha strongylata

Ragini, K., Piggott, A. M. & Karuso, P., Dec 2019, In : Marine Drugs. 17, 12, p. 1-14 14 p., 683.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Biological Products
New Zealand
Oceans and Seas

Chemical evolution: The 2018 Nobel Prize in Chemistry

Karuso, P., 2019, In : Chemistry in Australia. 2019, January/February, p. 14-19 6 p.

Research output: Contribution to journalArticleResearch


Is it time for artificial intelligence to predict the function of natural products based on 2D-structure

Liu, M., Karuso, P., Feng, Y., Kellenberger, E., Liu, F., Wang, C. & Quinn, R. J., 1 Oct 2019, In : MedChemComm. 10, 10, p. 1667-1677 11 p.

Research output: Contribution to journalReview articleResearchpeer-review

Artificial Intelligence
Biological Products
Artificial intelligence

Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate

Gotsbacher, M. P., Cho, S. M., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 19 Apr 2019, In : ACS Chemical Biology. 14, 4, p. 636-643 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cell death
Cell Death


Fellow of the Royal Australian Chemical Institute

Peter Karuso (Recipient), 12 Dec 2000

Prize: Honorary award


Fellow of the Royal Society of New South Wales

Peter Karuso (Recipient), 15 Jan 2016

Prize: Honorary award

honors and awards

Press / Media

Hyperdrive Science received the People’s Choice ‘Innovation IMPACT’ Award

Peter Karuso


1 item of media coverage, 3 media contributions

Press/Media: Public Engagement Activities


Deep Purple Total Protein Stain

Peter Karuso (Participant)

Impact: Economic impacts


Peter Karuso (Participant)

Impact: Economic impacts

Fluorotechnics Pty Ltd

Duncan Veal (Participant), Peter Karuso (Participant)

Impact: Economic impacts

Hyperdrive Science Pty Ltd

Peter Karuso (Participant), Fei Liu (Participant)

Impact: Economic impacts, Other impacts