• 2115 Citations
  • 27 h-Index
1984 …2020
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Research Outputs 1984 2019

2019

Chemical evolution: The 2018 Nobel Prize in Chemistry

Karuso, P., 2019, In : Chemistry in Australia. 2019, January/February, p. 14-19 6 p.

Research output: Contribution to journalArticleResearch

Molecules

Is it time for artificial intelligence to predict the function of natural products based on 2D-structure

Liu, M., Karuso, P., Feng, Y., Kellenberger, E., Liu, F., Wang, C. & Quinn, R. J., 1 Oct 2019, In : MedChemComm. 10, 10, p. 1667-1677 11 p.

Research output: Contribution to journalReview articleResearchpeer-review

Artificial Intelligence
Biological Products
Artificial intelligence
Metabolites

Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate

Gotsbacher, M. P., Cho, S. M., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 19 Apr 2019, In : ACS Chemical Biology. 14, 4, p. 636-643 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Artemisinins
Antimalarials
Proteomics
Cell death
Cell Death
2018

Banksialactones and banksiamarins: isochromanones and isocoumarins from an Australian fungus, Aspergillus banksianus

Chaudhary, N. K., Pitt, J. I., Lacey, E., Crombie, A., Vuong, D., Piggott, A. M. & Karuso, P., Jul 2018, In : Journal of Natural Products. 81, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Isocoumarins
Aspergillus
Metabolites
Fungi
Acids

Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions

Kwon, H. J. & Karuso, P., 9 Jan 2018, In : Proteome Science. 16, 1, p. 1-2 2 p., 1.

Research output: Contribution to journalEditorialResearch

Open Access
File

Expanding antibiotic chemical space around the nidulin pharmacophore

Morshed, M. T., Vuong, D., Crombie, A., Lacey, A. E., Karuso, P., Lacey, E. & Piggott, A. M., 28 Apr 2018, In : Organic and Biomolecular Chemistry. 16, 16, p. 3038-3051 14 p.

Research output: Contribution to journalArticleResearchpeer-review

antibiotics
analogs
Anti-Bacterial Agents
biosynthesis
fungi
Plasma (human)
Metabolites
Mass spectrometry
Mass Spectrometry
Pharmaceutical Preparations
2017

Antimalaria drug artesunate synergises with BH3 mimetic drug ABT-737 to kill multiple myeloma cell in vitro

Brennan, M., Gong, J., Kelly, G., Strasser, A., Liu, F., Karuso, P. & Herold, M., 9 Feb 2017, p. 127-127. 1 p.

Research output: Contribution to conferenceAbstractResearch

Crellasterones A and B: A-norsterol derivatives from the new caledonian sponge crella incrustans

Ragini, K., Piggott, A. M. & Karuso, P., 15 Jun 2017, In : Marine Drugs. 15, 6, p. 1-10 10 p., 177.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
New Caledonia
Porifera
Circular Dichroism
Biological Products
Nucleosides

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

Gotsbacher, M., Cho, S., Kwon, H. J. & Karuso, P., 1 Jul 2017, In : Proteome Science. 15, 1, p. 1-15 15 p., 16.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Daptomycin
Anti-Bacterial Agents
Bacteriophage T7
Assays
Bacteriophages

Dual emission fluorescent compounds

Karuso, P. & Chatterjee, S., 8 Sep 2017, IPC No. C07D 263/22 (2006.01), C07D 233/06 (2006.01), C07C 233/76 (2006.01), C07C 231/10 (2006.01), Patent No. WO/2017/147646, 28 Feb 2017, Priority date 29 Feb 2016, Priority No. 2016900739

Research output: PatentResearch

Open Access
Excited states
Wavelength
Patents and inventions
Chromophores
Molecules

Enantiodivergence in the biosynthesis of bromotyrosine alkaloids from sponges?

Ragini, K., Fromont, J., Piggott, A. M. & Karuso, P., 27 Jan 2017, In : Journal of Natural Products. 80, 1, p. 215-219 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Epicocconone–hemicyanine hybrids: near infrared fluorophores for protein staining and cell imaging

Karuso, P., Loa Kum Cheung, W., Peixoto, P. A., Boulangé, A. & Franck, X., 3 Feb 2017, In : Chemistry - A European Journal. 23, 8, p. 1820-1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorophores
Coloring Agents
Dyes
Staining and Labeling
Infrared radiation

Identifying the cellular targets of antibiotics using T7 phage display

Tirunagari, S., Vo, J., Karuso, P. & Piggott, A. M., 3 Apr 2017, p. 21. 1 p.

Research output: Contribution to conferencePosterResearch

Isolation and total synthesis of two novel metabolites from the fissurellid mollusc Scutus antipodes

Chand, S. & Karuso, P., 2017, In : Tetrahedron Letters. 58, 10, p. 1020-1023 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Molluscs
Mollusca
Metabolites
Gastropoda
Spectroscopic analysis

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part I

Karuso, P., 2017, In : Chemistry in Australia. 2017, February, p. 14-18 5 p.

Research output: Contribution to journalArticleResearch

Open Access
Catenanes
Rotaxanes
Isomerization

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part II

Karuso, P., 2017, In : Chemistry in Australia. 2017, March, p. 18-23 6 p.

Research output: Contribution to journalArticleResearch

Open Access
Nanorobots
Electron energy levels
Sensors

Synthesis of substituted oxo-azepines by regio - and diastereoselective hydroxylation

Spedding, H., Karuso, P. & Liu, F., Nov 2017, In : Molecules. 22, 11, p. 1-16 16 p., 1871.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Azepines
hydroboration
Hydroxylation
Regioselectivity
enzyme inhibitors
2016

An efficient and concise method to synthesize locked GFP chromophore analogues

Chatterjee, S. & Karuso, P., 23 Nov 2016, In : Tetrahedron Letters. 57, 47, p. 5197-5200 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromophores
Oxazolone
Lewis Acids
Condensation reactions
Heating

Artesunate targets the Bcl-2 antagonist of cell death promoter in humans

Karuso, P., Kwon, H. J., Gotsbacher, M., Cho, S., Kim, N. H. & Liu, F., 2016, p. 16-16. 1 p.

Research output: Contribution to conferenceAbstractResearch

Artesunate targets the Bcl-2 antagonist of cell death promoter in humans

Gotsbacher, M., Cho, S., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 2016, p. 28-29. 2 p.

Research output: Contribution to conferenceAbstractResearch

Banksialactones B-L, new isochromanones from Aspergillus banksianus

Chaudhary, N., Lacey, E., Piggott, A. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 28-28 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Concise synthesis and photophysical study of GFP analogues

Chatterjee, S., Datta, A. & Karuso, P., 2016. 1 p.

Research output: Contribution to conferenceAbstractResearch

Enantiodivergence in the biosynthesis of spiroisoxazoline bromotyrosine alkaloids

Ragini, K., Piggott, A. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 59-59 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Identifying the cellular targets of antibiotics using T7 phage display

Tirunagari, S., Vo, J., Karuso, P. & Piggott, A. M., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 66-66 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Identifying the cellular targets of natural products using T7 phage display

Piggott, A. M. & Karuso, P., 1 May 2016, In : Natural Product Reports. 33, 5, p. 626-636 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Bacteriophage T7
Bacteriophages
Biological Products
Display devices
Molecular biology

Structural basis to enantioselective proton transfer by acid-activated trifunctional organo-catalysts for catalytic proficiency

Kenny, R., Karuso, P., Varga, N., Senn, H. & Liu, F., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 7-7 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Synthesis of novel aminocoumarin-based pyrylium derivatives for advanced imaging applications

Ahire, K. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 16-16 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

The Chemistry of DNA repair: 2015 Nobel Prize in chemistry II

Karuso, P., 2016, In : Chemistry in Australia. p. 20-23 4 p.

Research output: Contribution to journalArticleResearch

Nobel Prize
DNA Repair

The Chemistry of DNA repair: 2015 Nobel Prize in Chemistry I

Karuso, P., 2016, In : Chemistry in Australia. 2016, Feburary, p. 14-17 4 p.

Research output: Contribution to journalArticleResearch

Repair
DNA
2015

Chemical investigation of bromotyrosine alkaloids from an Australia marine sponge Pseudoceratina cf verrucosa

Ragini, K. & Karuso, P., 2015, p. 26. 1 p.

Research output: Contribution to conferencePosterResearch

Chemical investigation of natural products from marine sponges

Ragini, K. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 53 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Excited state dynamics of brightly fluorescent second generation epicocconone analogues

Chatterjee, S., Karuso, P., Boulangé, A., Franck, X. & Datta, A., 21 May 2015, In : Journal of Physical Chemistry B. 119, 20, p. 6295-6303 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Excited states
Fluorescence
analogs
fluorescence
excitation

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

Hallen, A., Cooper, A. J. L., Jamie, J. F. & Karuso, P., 15 Jun 2015, In : Neurochemical Research. 40, 6, p. 1252-1266 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Catalysis
Thyroid Hormones
Enzymes
Pyrroline Carboxylate Reductases
Brain

Ketimine reductase/CRYM catalyzes reductive alkylamination of α-keto acids, confirming its function as an imine reductase

Hallen, A., Cooper, A. J. L., Smith, J. R., Jamie, J. F. & Karuso, P., 1 Nov 2015, In : Amino Acids. 47, 11, p. 2457-2461 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Keto Acids
Imines
Pyruvic Acid
Oxidoreductases
NADP

New antimicrobial bromotyrosine analogues from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis

Gotsbacher, M. P. & Karuso, P., 1 Mar 2015, In : Marine Drugs. 13, 3, p. 1389-1409 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Porifera
Mollusca
Alkaloids
Biological Assay
Anti-Bacterial Agents

New antimicrobial bromotyrosines from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis

Karuso, P. & Gotsbacher, M. P., 2015, p. 8. 1 p.

Research output: Contribution to conferenceAbstractResearch

New phenalenone analogues from a cryptic fungal co-culture leading to the biogenesis of duclauxamides

Chaudhary, N., Lacey, E., Piggott, A. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 22 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

New phenalenone dimers and monomer from Talaromyces bacillisporus

Chaudhary, N. K., Lacey, E., Piggott, A. M. & Karuso, P. H., 2015, p. 4. 1 p.

Research output: Contribution to conferencePosterResearch

Reverse chemical proteomics as a tool in natural product drug discovery

Piggott, A. M., Gotsbacher, M., Kwon, H. & Karuso, P., 2015, p. 16. 1 p.

Research output: Contribution to conferencePosterResearch

Reverse chemical proteomics with natural products for cellular and clinical applications

Karuso, P., Piggott, A. & Gotsbacher, M., 2015.

Research output: Contribution to conferencePaperResearch

Structural basis to enantioselective proton transfer by acid-activated trifunctional organocatalysts in the aza-Morita-Baylis-Hillman reaction

Kenny, R., Karuso, P., Senn, H. & Liu, F., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 43 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Super resolution microscopy: it's all about the molecules : 2014 Nobel Prize in Chemistry II

Karuso, P., 2015, In : Chemistry in Australia. 2015, March, p. 24-28 5 p.

Research output: Contribution to journalLetterResearch

chemistry
microscopy
probes
synthesis
molecules

Super resolution microscopy: it's all about the molecule

Karuso, P., 2015, In : Chemistry in Australia. 2015, February, p. 14-17 4 p.

Research output: Contribution to journalLetterResearch

Optical microscopy
Microscopic examination
Molecules

Synthesis of novel fluorescent labels for advanced imaging applications

Ahire, K. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 15 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

The Fluorescent natural product epicocconone

Karuso, P., 2015, p. 32-33. 2 p.

Research output: Contribution to conferenceAbstractResearch