• 2102 Citations
  • 27 h-Index
1984 …2020
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Research Outputs 1984 2019

2019

Chemical evolution: The 2018 Nobel Prize in Chemistry

Karuso, P., 2019, In : Chemistry in Australia. 2019, January/February, p. 14-19 6 p.

Research output: Contribution to journalArticleResearch

Molecules

Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate

Gotsbacher, M. P., Cho, S. M., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 19 Apr 2019, In : ACS Chemical Biology. 14, 4, p. 636-643 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Artemisinins
Antimalarials
Proteomics
Cell death
Cell Death
2018

Banksialactones and banksiamarins: isochromanones and isocoumarins from an Australian fungus, Aspergillus banksianus

Chaudhary, N. K., Pitt, J. I., Lacey, E., Crombie, A., Vuong, D., Piggott, A. M. & Karuso, P., Jul 2018, In : Journal of Natural Products. 81, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Isocoumarins
Aspergillus
Metabolites
Fungi
Acids

Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions

Kwon, H. J. & Karuso, P., 9 Jan 2018, In : Proteome Science. 16, 1, p. 1-2 2 p., 1.

Research output: Contribution to journalEditorialResearch

Open Access
File

Expanding antibiotic chemical space around the nidulin pharmacophore

Morshed, M. T., Vuong, D., Crombie, A., Lacey, A. E., Karuso, P., Lacey, E. & Piggott, A. M., 28 Apr 2018, In : Organic and Biomolecular Chemistry. 16, 16, p. 3038-3051 14 p.

Research output: Contribution to journalArticleResearchpeer-review

antibiotics
analogs
Anti-Bacterial Agents
biosynthesis
fungi
Plasma (human)
Metabolites
Mass spectrometry
Mass Spectrometry
Pharmaceutical Preparations
2017

Antimalaria drug artesunate synergises with BH3 mimetic drug ABT-737 to kill multiple myeloma cell in vitro

Brennan, M., Gong, J., Kelly, G., Strasser, A., Liu, F., Karuso, P. & Herold, M., 9 Feb 2017, p. 127-127. 1 p.

Research output: Contribution to conferenceAbstractResearch

Crellasterones A and B: A-norsterol derivatives from the new caledonian sponge crella incrustans

Ragini, K., Piggott, A. M. & Karuso, P., 15 Jun 2017, In : Marine Drugs. 15, 6, p. 1-10 10 p., 177.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
New Caledonia
Porifera
Circular Dichroism
Biological Products
Nucleosides

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

Gotsbacher, M., Cho, S., Kwon, H. J. & Karuso, P., 1 Jul 2017, In : Proteome Science. 15, 1, p. 1-15 15 p., 16.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Daptomycin
Anti-Bacterial Agents
Bacteriophage T7
Assays
Bacteriophages

Dual emission fluorescent compounds

Karuso, P. & Chatterjee, S., 8 Sep 2017, IPC No. C07D 263/22 (2006.01), C07D 233/06 (2006.01), C07C 233/76 (2006.01), C07C 231/10 (2006.01), Patent No. WO/2017/147646, 28 Feb 2017, Priority date 29 Feb 2016, Priority No. 2016900739

Research output: PatentResearch

Open Access
Excited states
Wavelength
Patents and inventions
Chromophores
Molecules

Enantiodivergence in the biosynthesis of bromotyrosine alkaloids from sponges?

Ragini, K., Fromont, J., Piggott, A. M. & Karuso, P., 27 Jan 2017, In : Journal of Natural Products. 80, 1, p. 215-219 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Epicocconone–hemicyanine hybrids: near infrared fluorophores for protein staining and cell imaging

Karuso, P., Loa Kum Cheung, W., Peixoto, P. A., Boulangé, A. & Franck, X., 3 Feb 2017, In : Chemistry - A European Journal. 23, 8, p. 1820-1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorophores
Coloring Agents
Dyes
Staining and Labeling
Infrared radiation

Identifying the cellular targets of antibiotics using T7 phage display

Tirunagari, S., Vo, J., Karuso, P. & Piggott, A. M., 3 Apr 2017, p. 21. 1 p.

Research output: Contribution to conferencePosterResearch

Isolation and total synthesis of two novel metabolites from the fissurellid mollusc Scutus antipodes

Chand, S. & Karuso, P., 2017, In : Tetrahedron Letters. 58, 10, p. 1020-1023 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Molluscs
Mollusca
Metabolites
Gastropoda
Spectroscopic analysis

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part II

Karuso, P., 2017, In : Chemistry in Australia. 2017, March, p. 18-23 6 p.

Research output: Contribution to journalArticleResearch

Open Access
Nanorobots
Electron energy levels
Sensors

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part I

Karuso, P., 2017, In : Chemistry in Australia. 2017, February, p. 14-18 5 p.

Research output: Contribution to journalArticleResearch

Open Access
Catenanes
Rotaxanes
Isomerization

Synthesis of substituted oxo-azepines by regio - and diastereoselective hydroxylation

Spedding, H., Karuso, P. & Liu, F., Nov 2017, In : Molecules. 22, 11, p. 1-16 16 p., 1871.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Azepines
hydroboration
Hydroxylation
Regioselectivity
enzyme inhibitors
2016

An efficient and concise method to synthesize locked GFP chromophore analogues

Chatterjee, S. & Karuso, P., 23 Nov 2016, In : Tetrahedron Letters. 57, 47, p. 5197-5200 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromophores
Oxazolone
Lewis Acids
Condensation reactions
Heating

Artesunate targets the Bcl-2 antagonist of cell death promoter in humans

Gotsbacher, M., Cho, S., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 2016, p. 28-29. 2 p.

Research output: Contribution to conferenceAbstractResearch

Artesunate targets the Bcl-2 antagonist of cell death promoter in humans

Karuso, P., Kwon, H. J., Gotsbacher, M., Cho, S., Kim, N. H. & Liu, F., 2016, p. 16-16. 1 p.

Research output: Contribution to conferenceAbstractResearch

Banksialactones B-L, new isochromanones from Aspergillus banksianus

Chaudhary, N., Lacey, E., Piggott, A. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 28-28 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Concise synthesis and photophysical study of GFP analogues

Chatterjee, S., Datta, A. & Karuso, P., 2016. 1 p.

Research output: Contribution to conferenceAbstractResearch

Enantiodivergence in the biosynthesis of spiroisoxazoline bromotyrosine alkaloids

Ragini, K., Piggott, A. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 59-59 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Identifying the cellular targets of antibiotics using T7 phage display

Tirunagari, S., Vo, J., Karuso, P. & Piggott, A. M., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 66-66 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Identifying the cellular targets of natural products using T7 phage display

Piggott, A. M. & Karuso, P., 1 May 2016, In : Natural Product Reports. 33, 5, p. 626-636 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Bacteriophage T7
Bacteriophages
Biological Products
Display devices
Molecular biology

Structural basis to enantioselective proton transfer by acid-activated trifunctional organo-catalysts for catalytic proficiency

Kenny, R., Karuso, P., Varga, N., Senn, H. & Liu, F., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 7-7 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Synthesis of novel aminocoumarin-based pyrylium derivatives for advanced imaging applications

Ahire, K. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 16-16 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

The Chemistry of DNA repair: 2015 Nobel Prize in Chemistry I

Karuso, P., 2016, In : Chemistry in Australia. 2016, Feburary, p. 14-17 4 p.

Research output: Contribution to journalArticleResearch

Repair
DNA

The Chemistry of DNA repair: 2015 Nobel Prize in chemistry II

Karuso, P., 2016, In : Chemistry in Australia. p. 20-23 4 p.

Research output: Contribution to journalArticleResearch

Nobel Prize
DNA Repair
2015

Chemical investigation of bromotyrosine alkaloids from an Australia marine sponge Pseudoceratina cf verrucosa

Ragini, K. & Karuso, P., 2015, p. 26. 1 p.

Research output: Contribution to conferencePosterResearch

Chemical investigation of natural products from marine sponges

Ragini, K. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 53 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Excited state dynamics of brightly fluorescent second generation epicocconone analogues

Chatterjee, S., Karuso, P., Boulangé, A., Franck, X. & Datta, A., 21 May 2015, In : Journal of Physical Chemistry B. 119, 20, p. 6295-6303 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Excited states
Fluorescence
analogs
fluorescence
excitation

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

Hallen, A., Cooper, A. J. L., Jamie, J. F. & Karuso, P., 15 Jun 2015, In : Neurochemical Research. 40, 6, p. 1252-1266 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Catalysis
Thyroid Hormones
Enzymes
Pyrroline Carboxylate Reductases
Brain

Ketimine reductase/CRYM catalyzes reductive alkylamination of α-keto acids, confirming its function as an imine reductase

Hallen, A., Cooper, A. J. L., Smith, J. R., Jamie, J. F. & Karuso, P., 1 Nov 2015, In : Amino Acids. 47, 11, p. 2457-2461 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Keto Acids
Imines
Pyruvic Acid
Oxidoreductases
NADP

New antimicrobial bromotyrosine analogues from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis

Gotsbacher, M. P. & Karuso, P., 1 Mar 2015, In : Marine Drugs. 13, 3, p. 1389-1409 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Porifera
Mollusca
Alkaloids
Biological Assay
Anti-Bacterial Agents

New antimicrobial bromotyrosines from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis

Karuso, P. & Gotsbacher, M. P., 2015, p. 8. 1 p.

Research output: Contribution to conferenceAbstractResearch

New phenalenone analogues from a cryptic fungal co-culture leading to the biogenesis of duclauxamides

Chaudhary, N., Lacey, E., Piggott, A. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 22 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

New phenalenone dimers and monomer from Talaromyces bacillisporus

Chaudhary, N. K., Lacey, E., Piggott, A. M. & Karuso, P. H., 2015, p. 4. 1 p.

Research output: Contribution to conferencePosterResearch

Reverse chemical proteomics as a tool in natural product drug discovery

Piggott, A. M., Gotsbacher, M., Kwon, H. & Karuso, P., 2015, p. 16. 1 p.

Research output: Contribution to conferencePosterResearch

Reverse chemical proteomics with natural products for cellular and clinical applications

Karuso, P., Piggott, A. & Gotsbacher, M., 2015.

Research output: Contribution to conferencePaperResearch

Structural basis to enantioselective proton transfer by acid-activated trifunctional organocatalysts in the aza-Morita-Baylis-Hillman reaction

Kenny, R., Karuso, P., Senn, H. & Liu, F., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 43 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Super resolution microscopy: it's all about the molecules : 2014 Nobel Prize in Chemistry II

Karuso, P., 2015, In : Chemistry in Australia. 2015, March, p. 24-28 5 p.

Research output: Contribution to journalLetterResearch

chemistry
microscopy
probes
synthesis
molecules

Super resolution microscopy: it's all about the molecule

Karuso, P., 2015, In : Chemistry in Australia. 2015, February, p. 14-17 4 p.

Research output: Contribution to journalLetterResearch

Optical microscopy
Microscopic examination
Molecules

Synthesis of novel fluorescent labels for advanced imaging applications

Ahire, K. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 15 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

The Fluorescent natural product epicocconone

Karuso, P., 2015, p. 32-33. 2 p.

Research output: Contribution to conferenceAbstractResearch

Understanding the fluorescent natural product epicocconone

Karuso, P., Chatterjee, S., Datta, A., Choi, Y-H., Veal, D. A., Mackintosh, J. A., Coghlan, D. R., Cleemann, F., Boulange, A., Peixoto, P. & Franck, X., 2015, p. 17. 1 p.

Research output: Contribution to conferencePosterResearch