• 2140 Citations
  • 27 h-Index
1984 …2020
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Research Outputs 1984 2020

Rapid and sensitive fluorescent peptide quantification using epicocconone

Karuso, P. H., Crawford, A. S., Chen, D. E., Meheigh, R. J., Geppo, B. S., Scott, G. B., Mackintosh, J., Veal, D. A. & Choi, H., 2006, In : Journal of biomolecular techniques : ABRF 2006 poster abstracts. 17, 1, p. 52 1 p.

Research output: Contribution to journalMeeting abstractResearch

Peptides
Assays
Mass spectrometry
Proteins
Fluorescence

Rapid identification of a protein binding partner for the marine natural product kahalalide F by using reverse chemical proteomics

Piggott, A. M. & Karuso, P., 3 Mar 2008, In : ChemBioChem. 9, 4, p. 524-530 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display

Piggott, A. M., Kriegel, A. M., Willows, R. D. & Karuso, P., 1 Oct 2009, In : Bioorganic and Medicinal Chemistry. 17, 19, p. 6841-6850 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tacrolimus Binding Proteins
Bacteriophage T7
Bacteriophages
Complementary DNA
Display devices

Rapid screening of the antimicrobial activity of extracts and natural products

Chand, S., Lusunzi, I., Williams, L. R., Karuso, P. & Veal, D. A., 1994, In : The Journal of Antibiotics. 47, 11, p. 1295-1304 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Biological Products
Carboxylesterase
Volatile Oils
Complex Mixtures
Biological Assay

Real-time fluorescence monitoring of tryptic digestion in proteomics

Karuso, P., Crawford, A. S., Veal, D. A., Scott, G. B. I. & Choi, H. Y., Jan 2008, In : Journal of Proteome Research. 7, 1, p. 361-366 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomics
Proteolysis
Digestion
Fluorescence
Monitoring

Real-time Monitoring and Quantification of Proteolytic Digestion for Shotgun Proteomics

Choi, H-Y., Veal, D. A., Cooney, B., David, S. & Karuso, P., 2007, In : Abstracts Volume for HUPO 6th Annual World Congress. p. 29-29 1 p.

Research output: Contribution to journalMeeting abstractResearch

Real-time monitoring of tryptic digests using the fluorophore epicocconone

Choi, H., Crawford, A. S., Chen, D. E., Meheigh, R. J., Wildsmith, J., Ray, K. M., Scott, G. B. I., Mackintosh, J., Veal, D. A. & Karuso, P. H., 2006, In : Journal of biomolecular techniques : ABRF 2006 poster abstracts. 17, 1, p. 67 1 p.

Research output: Contribution to journalMeeting abstractResearch

Fluorophores
Proteolysis
Peptide Hydrolases
Mass spectrometry
Monitoring

Recombinant prespore-specific antigen from Dictyostelium discoideum is a β-sheet glycoprotein with a spacer peptide modified by O-linked N-acetylglucosamine

Zachara, N. E., Packer, N. H., Temple, M. D., Slade, M. B., Jardine, D. R., Karuso, P., Moss, C. J., Mabbutt, B. C., Curmi, P. M. G., Williams, K. L. & Gooley, A. A., 1996, In : European Journal of Biochemistry. 238, 2, p. 511-518 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Acetylglucosamine
Glycoproteins
Glycosylation
Antigens
Peptides

Reverse Chemical Proteomics: identifying Novel Drug Receptors Using T7 Phage Display and Marine Natural Products

Piggott, A. & Karuso, P., 2003, p. 214-214. 1 p.

Research output: Contribution to conferenceAbstractResearch

Reverse Chemical Proteomics and Biomimetic Synthesis in the Discovery of Bioactive Marine Natural Products

Karuso, P., 2007, p. 89-89. 1 p.

Research output: Contribution to conferenceAbstractResearch

Reverse chemical proteomics as a tool in natural product drug discovery

Piggott, A. M., Gotsbacher, M., Kwon, H. & Karuso, P., 2015, p. 16. 1 p.

Research output: Contribution to conferencePosterResearch

Reverse chemical proteomics as tool in drug discovery

Gotsbacher, M. & Karuso, P., 2011, p. 52. 1 p.

Research output: Contribution to conferenceAbstractResearch

Reverse chemical proteomics as tool in drug discovery

Karuso, P., 2013, p. PS30-02. 1 p.

Research output: Contribution to conferenceAbstractResearch

Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate

Gotsbacher, M. P., Cho, S. M., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 19 Apr 2019, In : ACS Chemical Biology. 14, 4, p. 636-643 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Artemisinins
Antimalarials
Proteomics
Cell death
Cell Death

Reverse chemical proteomics in drug discovery

Gotsbacher, M. & Karuso, P., 2009, In : Scientia Pharmaceutica. 77, 1, p. 194 1 p.

Research output: Contribution to journalMeeting abstractResearch

Reverse Chemical Proteomics in the Discovery of Cellular Receptors for Natural Products

Karuso, P., 2005, p. 16-17. 2 p.

Research output: Contribution to conferenceAbstractResearch

Reverse chemical proteomics with natural products for cellular and clinical applications

Karuso, P., Piggott, A. & Gotsbacher, M., 2015.

Research output: Contribution to conferencePaperResearch

Reversible covalent binding of the fluorophore epicocconone to proteins provides a novel approach to the sensitive quantification of proteins across a wide variety of different platforms

Veal, D., Mackintosh, J., Coghlan, D., Choi, Y. & Karuso, P., Aug 2005, In : Molecular and Cellular Proteomics. 4, 8S1, p. S380-S380 1 p.

Research output: Contribution to journalMeeting abstractResearchpeer-review

Reversible Covalent Binding of the Fluorophore Epicocconone to Proteins provides a Novel Approach to the Sensitive Quantification of Proteins Across a Wide Variety of Different Platforms

Veal, D. A., Karuso, P., Choi, Y., Mackintosh, J. A. & Coghlan, D. R., 2005, p. 1-1. 1 p.

Research output: Contribution to conferenceAbstractResearch

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part II

Karuso, P., 2017, In : Chemistry in Australia. 2017, March, p. 18-23 6 p.

Research output: Contribution to journalArticleResearch

Open Access
Nanorobots
Electron energy levels
Sensors

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part I

Karuso, P., 2017, In : Chemistry in Australia. 2017, February, p. 14-18 5 p.

Research output: Contribution to journalArticleResearch

Open Access
Catenanes
Rotaxanes
Isomerization

Room-temperature dual fluorescence of a locked green fluorescent protein chromophore analogue

Chatterjee, S., Ahire, K. & Karuso, P., 15 Jan 2020, In : Journal of the American Chemical Society. 142, 2, p. 738-749 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromophores
Green Fluorescent Proteins
Fluorescence
Proteins
Isomers

Rules for the addition of O-linked N-acetylglucosamine to secreted proteins in Dictyostelium discoideum: In vivo studies on glycosylation of mucin MUC1 and MUC2 repeats

Jung, E., Gooley, A. A., Packer, N. H., Karuso, P. & Williams, K. L., 15 Apr 1998, In : European Journal of Biochemistry. 253, 2, p. 517-524 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycosylation
Dictyostelium
Acetylglucosamine
Mucins
Peptides

Secondary metabolites from Basotho medicinal plants. I. Bulbine narcissifolia

Qhotsokoane-Lusunzi, M. A. & Karuso, P., 2001, In : Journal of Natural Products. 64, 10, p. 1368-1372 5 p.

Research output: Contribution to journalArticleResearchpeer-review

acetosyringone
laxatives
anthraquinones
Medicinal Plants
Metabolites

Secondary Metabolites from Basotho Medicinal Plants. II Bulbine capitata

Qhotsokoane-Lusunzi, M. A. & Karuso, P., 2001, In : Australian Journal of Chemistry. 54, 7, p. 427-430 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Anthraquinones
Metabolites
Cathartics
Laxatives
Glycosides

Seeing is believing: 3D visualisation in the teaching of complex concepts in organic chemistry

Karuso, P., McRae, C. R. & Liu, F., 2011, p. 6. 1 p.

Research output: Contribution to conferenceAbstractResearch

Site-directed mutagenesis and high-resolution NMR spectroscopy of the active site of porphobilinogen deaminase

Scott, A. I., Roessner, C. A., Stolowich, N. J., Karuso, P., Williams, H. J., Grant, S. K., Gonzalez, M. D. & Hoshino, T., 1988, In : Biochemistry. 27, 21, p. 7984-7990 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Hydroxymethylbilane Synthase
Porphobilinogen
Mutagenesis
Site-Directed Mutagenesis
Nuclear magnetic resonance spectroscopy

Site-directed mutagenesis and high-resolution NMR-spectroscopy of the active-site of porphobilinogen deaminase

Scott, A. I., Roessner, C. A., Clemens, K., Stolowich, N. J., Karuso, P., Williams, H. J., Grant, S. K., Pichon, C., Santander, P., Gonzalez, M. D. & Hoshino, T., 1990, In : Molecular Aspects of Medicine. 11, 1-2, p. 142-142 1 p.

Research output: Contribution to journalMeeting abstractResearchpeer-review

Solution structure and behaviour of Δ-m-α-[Ru(R,R- picchxnMe2)(phi)]2+ by NMR spectroscopy and molecular modelling

Proudfoot, E. M., Mackay, J. P. & Karuso, P., 21 Jan 2003, In : Dalton Transactions. 2, p. 165-170 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular modeling
Isomers
Nuclear magnetic resonance spectroscopy
Protons
Association reactions

Solution structure of FK 506 from nuclear magnetic resonance and molecular dynamics

Karuso, P., Kessler, H. & Mierke, D. F., 1990, In : Journal of the American Chemical Society. 112, 25, p. 9434-9436 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Sphingomonas paucimobilis BPSI-3 mutant AN2 produces a red catabolite during biphenyl degradation

Davison, A. D., Gillings, M. R., Jardine, D. R., Karuso, P., Nouwens, A. S., French, J. J., Veal, D. A. & Altavilla, N., 1999, In : Journal of Industrial Microbiology and Biotechnology. 23, 4-5, p. 314-319 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Sphingomonas
Spectrophotometry
Gas chromatography
Degradation
Mutagenesis

Sterol composition and classification of the Porifera

Bergquist, P. R., Karuso, P., Cambie, R. C. & Smith, D. J., 1991, In : Biochemical Systematics and Ecology. 19, 1, p. 17-24 8 p.

Research output: Contribution to journalArticleResearchpeer-review

sterol
Porifera
Sterols
sponge
sterols

Structural basis to enantioselective proton transfer by acid-activated trifunctional organo-catalysts for catalytic proficiency

Kenny, R., Karuso, P., Varga, N., Senn, H. & Liu, F., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 7-7 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Structural basis to enantioselective proton transfer by acid-activated trifunctional organocatalysts in the aza-Morita-Baylis-Hillman reaction

Kenny, R., Karuso, P., Senn, H. & Liu, F., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 43 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Structure determination of aplyviolene from chelonaplysilla-violacea

Buckleton, J. S., Bergquist, P. R., Cambie, R. C., Clark, G. R., Karuso, P. & Rickard, C. E. F., 15 Dec 1986, In : Acta Crystallographica. Section C: Crystal Structure Communications. 42, p. 1846-1848 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure of tetrahydroaplysulfurin-1

Buckleton, J. S., Bergquist, P. R., Cambie, R. C., Clark, G. R., Karuso, P. & Rickard, C. E. F., 15 Dec 1987, In : Acta Crystallographica. Section C: Crystal Structure Communications. 43, p. 2430-2432 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Super resolution microscopy: it's all about the molecule

Karuso, P., 2015, In : Chemistry in Australia. 2015, February, p. 14-17 4 p.

Research output: Contribution to journalLetterResearch

Optical microscopy
Microscopic examination
Molecules

Super resolution microscopy: it's all about the molecules : 2014 Nobel Prize in Chemistry II

Karuso, P., 2015, In : Chemistry in Australia. 2015, March, p. 24-28 5 p.

Research output: Contribution to journalLetterResearch

chemistry
microscopy
probes
synthesis
molecules

Synergistic growth of two members from a mixed microbial consortium growing on biphenyl

Davison, A. D., Csellner, H., Karuso, P. & Veal, D. A., 1994, In : FEMS Microbiology Ecology. 14, 2, p. 133-146 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Microbial Consortia
Coculture Techniques
Sphingomonas
Growth
Biphenyl Compounds

Synthesis of ageladine A, analogs and their biological screening

Shengule, S. R. & Karuso, P., 25 Mar 2007, In : Abstracts of papers of the american chemical society. 233, p. 744-744 1 p.

Research output: Contribution to journalMeeting abstractResearchpeer-review

Synthesis of Ageladine A, analogues and their biological activities

Shengule, S. R. & Karuso, P., 2007, Conference Programme & Proceedings. Queenstown, New Zealand, p. 183-183 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Synthesis of Ageladine A, analogues and their biological activities

Shengule, S. R. & Karuso, P., 2007, p. Medi 182-Medi 182. 1 p.

Research output: Contribution to conferenceAbstractResearch

Synthesis of ageladine A and analogs thereof

Karuso, P. & Shengule, S. R., 23 Jun 2011, IPC No. A61K 31/437, Patent No. US20110152313, Priority date 20 Jun 2008, Priority No. 2008903152

Research output: PatentResearch

Condensation
Patents and inventions
Aldehydes
Ageladine A

Synthesis of ageladine A and analogs thereof

Karuso, P. & Shengule, S., 23 Dec 2009, IPC No. C07D 471/04, Patent No. WO2009152584, Priority date 20 Jun 2008, Priority No. 2008903152

Research output: PatentResearch

Condensation
Patents and inventions
Aldehydes
Ageladine A

Synthesis of a new hydrophilic o-nitrobenzyl photocleavable linker suitable for use in chemical proteomics

Piggott, A. M. & Karuso, P., 21 Nov 2005, In : Tetrahedron Letters. 46, 47, p. 8241-8244 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Solid-Phase Synthesis Techniques
Photolysis
Ultraviolet Rays
Proteomics
Biological systems

Synthesis of new BINAP-based aminophosphines and their 31P-NMR spectroscopy

Anstiss, C., Karuso, P., Richardson, M. & Liu, F., Mar 2013, In : Molecules. 18, 3, p. 2788-2802 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Ligands
nuclear magnetic resonance
ligands

Synthesis of novel aminocoumarin-based pyrylium derivatives for advanced imaging applications

Ahire, K. M. & Karuso, P., 2016, The Royal Australian Chemical Institute NSW Organic Chemistry Group: 37th Annual One-Day Symposium : program and book of abstracts. Karuso, P., Try, A. & Piggott, A. (eds.). Melbourne: Royal Australian Chemical Institute, p. 16-16 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Synthesis of novel fluorescent labels for advanced imaging applications

Ahire, K. & Karuso, P., 2015, RACI NSW Organic Chemistry Group 36th annual one-day symposium: programme. Melbourne: Royal Australian Chemical Institute, p. 15 1 p.

Research output: Chapter in Book/Report/Conference proceedingOther chapter contributionResearch

Synthesis of Peptidyl Sulfinamides and Sulfenamides as Novel Inhibitors of Cysteine Proteases

Lim, J., Lewis, N. & Karuso, P., 2000, p. 20-20. 1 p.

Research output: Contribution to conferenceAbstractResearch