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1984 …2020
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Research Outputs 1984 2019

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2019

Chemical evolution: The 2018 Nobel Prize in Chemistry

Karuso, P., 2019, In : Chemistry in Australia. 2019, January/February, p. 14-19 6 p.

Research output: Contribution to journalArticleResearch

Molecules

Reverse chemical proteomics identifies an unanticipated human target of the antimalarial artesunate

Gotsbacher, M. P., Cho, S. M., Kim, N. H., Liu, F., Kwon, H. J. & Karuso, P., 19 Apr 2019, In : ACS Chemical Biology. 14, 4, p. 636-643 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Artemisinins
Antimalarials
Proteomics
Cell death
Cell Death
2018

Banksialactones and banksiamarins: isochromanones and isocoumarins from an Australian fungus, Aspergillus banksianus

Chaudhary, N. K., Pitt, J. I., Lacey, E., Crombie, A., Vuong, D., Piggott, A. M. & Karuso, P., Jul 2018, In : Journal of Natural Products. 81, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Isocoumarins
Aspergillus
Metabolites
Fungi
Acids

Expanding antibiotic chemical space around the nidulin pharmacophore

Morshed, M. T., Vuong, D., Crombie, A., Lacey, A. E., Karuso, P., Lacey, E. & Piggott, A. M., 28 Apr 2018, In : Organic and Biomolecular Chemistry. 16, 16, p. 3038-3051 14 p.

Research output: Contribution to journalArticleResearchpeer-review

antibiotics
analogs
Anti-Bacterial Agents
biosynthesis
fungi
Plasma (human)
Metabolites
Mass spectrometry
Mass Spectrometry
Pharmaceutical Preparations
2017

Crellasterones A and B: A-norsterol derivatives from the new caledonian sponge crella incrustans

Ragini, K., Piggott, A. M. & Karuso, P., 15 Jun 2017, In : Marine Drugs. 15, 6, p. 1-10 10 p., 177.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
New Caledonia
Porifera
Circular Dichroism
Biological Products
Nucleosides

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

Gotsbacher, M., Cho, S., Kwon, H. J. & Karuso, P., 1 Jul 2017, In : Proteome Science. 15, 1, p. 1-15 15 p., 16.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Daptomycin
Anti-Bacterial Agents
Bacteriophage T7
Assays
Bacteriophages

Enantiodivergence in the biosynthesis of bromotyrosine alkaloids from sponges?

Ragini, K., Fromont, J., Piggott, A. M. & Karuso, P., 27 Jan 2017, In : Journal of Natural Products. 80, 1, p. 215-219 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Epicocconone–hemicyanine hybrids: near infrared fluorophores for protein staining and cell imaging

Karuso, P., Loa Kum Cheung, W., Peixoto, P. A., Boulangé, A. & Franck, X., 3 Feb 2017, In : Chemistry - A European Journal. 23, 8, p. 1820-1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorophores
Coloring Agents
Dyes
Staining and Labeling
Infrared radiation

Isolation and total synthesis of two novel metabolites from the fissurellid mollusc Scutus antipodes

Chand, S. & Karuso, P., 2017, In : Tetrahedron Letters. 58, 10, p. 1020-1023 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Molluscs
Mollusca
Metabolites
Gastropoda
Spectroscopic analysis

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part I

Karuso, P., 2017, In : Chemistry in Australia. 2017, February, p. 14-18 5 p.

Research output: Contribution to journalArticleResearch

Open Access
Catenanes
Rotaxanes
Isomerization

Rise of the machines: the 2016 Nobel Prize in Chemistry. Part II

Karuso, P., 2017, In : Chemistry in Australia. 2017, March, p. 18-23 6 p.

Research output: Contribution to journalArticleResearch

Open Access
Nanorobots
Electron energy levels
Sensors

Synthesis of substituted oxo-azepines by regio - and diastereoselective hydroxylation

Spedding, H., Karuso, P. & Liu, F., Nov 2017, In : Molecules. 22, 11, p. 1-16 16 p., 1871.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Azepines
hydroboration
Hydroxylation
Regioselectivity
enzyme inhibitors
2016

An efficient and concise method to synthesize locked GFP chromophore analogues

Chatterjee, S. & Karuso, P., 23 Nov 2016, In : Tetrahedron Letters. 57, 47, p. 5197-5200 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Chromophores
Oxazolone
Lewis Acids
Condensation reactions
Heating

Identifying the cellular targets of natural products using T7 phage display

Piggott, A. M. & Karuso, P., 1 May 2016, In : Natural Product Reports. 33, 5, p. 626-636 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Bacteriophage T7
Bacteriophages
Biological Products
Display devices
Molecular biology

The Chemistry of DNA repair: 2015 Nobel Prize in Chemistry I

Karuso, P., 2016, In : Chemistry in Australia. 2016, Feburary, p. 14-17 4 p.

Research output: Contribution to journalArticleResearch

Repair
DNA

The Chemistry of DNA repair: 2015 Nobel Prize in chemistry II

Karuso, P., 2016, In : Chemistry in Australia. p. 20-23 4 p.

Research output: Contribution to journalArticleResearch

Nobel Prize
DNA Repair
2015

Excited state dynamics of brightly fluorescent second generation epicocconone analogues

Chatterjee, S., Karuso, P., Boulangé, A., Franck, X. & Datta, A., 21 May 2015, In : Journal of Physical Chemistry B. 119, 20, p. 6295-6303 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Excited states
Fluorescence
analogs
fluorescence
excitation

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

Hallen, A., Cooper, A. J. L., Jamie, J. F. & Karuso, P., 15 Jun 2015, In : Neurochemical Research. 40, 6, p. 1252-1266 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Catalysis
Thyroid Hormones
Enzymes
Pyrroline Carboxylate Reductases
Brain

Ketimine reductase/CRYM catalyzes reductive alkylamination of α-keto acids, confirming its function as an imine reductase

Hallen, A., Cooper, A. J. L., Smith, J. R., Jamie, J. F. & Karuso, P., 1 Nov 2015, In : Amino Acids. 47, 11, p. 2457-2461 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Keto Acids
Imines
Pyruvic Acid
Oxidoreductases
NADP

New antimicrobial bromotyrosine analogues from the sponge Pseudoceratina purpurea and its predator Tylodina corticalis

Gotsbacher, M. P. & Karuso, P., 1 Mar 2015, In : Marine Drugs. 13, 3, p. 1389-1409 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Porifera
Mollusca
Alkaloids
Biological Assay
Anti-Bacterial Agents
2014

Characterisation of a novel UV filter in the lens of the thirteen-lined ground squirrel (Ictidomys tridecemlineatus)

Lyons, B., Karuso, P., Jamie, J. F., Simpanya, M. F., Giblin, F. & Truscott, R. J. W., 2014, In : Experimental Eye Research. 121, p. 114-120 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Sciuridae
Lenses
Kynurenine
Proline
Tryptophan

Design and synthesis of epicocconone analogues with improved fluorescence properties

Peixoto, P. A., Boulangé, A., Ball, M., Naudin, B., Alle, T., Cosette, P., Karuso, P. & Franck, X., 29 Oct 2014, In : Journal of the American Chemical Society. 136, 43, p. 15248-15256 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorophores
Fluorescence
Quantum yield
Biological Products
Proteomics

Diastereoselective Pictet-Spengler reactions of a tethered 2-aminoimidazole

Shengule, S. R. & Karuso, P., 2014, In : Australian Journal of Chemistry. 67, 2, p. 184-191 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Stereochemistry
Aldehydes
Amino Acids
Lewis Acids
Molecular modeling

Getting to know big molecules: 2013 Nobel Prize in Chemistry I

Karuso, P., 2014, In : Chemistry in Australia. 2014, February, p. 12-15 4 p.

Research output: Contribution to journalArticleResearch

Molecules
Enzymes

Getting to know big molecules: 2013 Nobel Prize in Chemistry II

Karuso, P., 2014, In : Chemistry in Australia. 2014, March, p. 16-20 5 p.

Research output: Contribution to journalArticleResearch

Molecules
Enzymes
2013

G-Protein-coupled receptors: 2012 Nobel Prize in Chemistry II

Karuso, P., 2013, In : Chemistry in Australia. 2013, March, p. 16-19 4 p.

Research output: Contribution to journalArticleResearch

Triptych
Crystallization
Nobel Prize
Protein

G-Protein-coupled receptors: 2012 Nobel prize in chemistry I

Karuso, P., 2013, In : Chemistry in Australia. 2013, February, p. 16-19 4 p.

Research output: Contribution to journalArticleResearch

Cells
Nobel Prize
Protein

Synthesis of new BINAP-based aminophosphines and their 31P-NMR spectroscopy

Anstiss, C., Karuso, P., Richardson, M. & Liu, F., Mar 2013, In : Molecules. 18, 3, p. 2788-2802 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
Ligands
nuclear magnetic resonance
ligands

The role of different structural motifs in the ultrafast dynamics of second generation protein stains

Chatterjee, S., Karuso, P., Boulangé, A., Peixoto, P. A., Franck, X. & Datta, A., 5 Dec 2013, In : Journal of Physical Chemistry B. 117, 48, p. 14951-14959 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorophores
Coloring Agents
Fluorescence
proteins
Proteins
2012

ChemVoyage: A web-based, simulated learning environment with scaffolding and linking visualization to conceptualization

McRae, C., Karuso, P. & Liu, F., 12 Jun 2012, In : Journal of Chemical Education. 89, 7, p. 878-883 6 p.

Research output: Contribution to journalArticleResearchpeer-review

visualization
learning environment
Visualization
Students
learning

Quasicrystals or quasiscience? 2011 Nobel prize in chemistry II

Karuso, P., 2012, In : Chemistry in Australia. 79, 2, p. 16-21 6 p.

Research output: Contribution to journalArticleResearch

Quasicrystals or Quasiscience? 2011 Nobel prize in chemistry I

Karuso, P., 2012, In : Chemistry in Australia. 79, 1, p. 18-21 4 p.

Research output: Contribution to journalArticleResearch

Microscope
Receipt
Nobel Prize
Physical

The transposing of isomer yields in the methanolyses of N-substituted quinolinimides by triethylamine

Van Es, T., Staskun, B. & Karuso, P., 2012, In : South African Journal of Chemistry. 65, p. 53-61 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Isomers
Esters
triethylamine
2011

A one-pot synthesis and biological activity of ageladine A and analogues

Shengule, S. R., Loa-Kum-Cheung, W. L., Parish, C. R., Blairvacq, M., Meijer, L., Nakao, Y. & Karuso, P., 14 Apr 2011, In : Journal of Medicinal Chemistry. 54, 7, p. 2492-2503 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Metalloproteases
Phosphotransferases
Structure-Activity Relationship
Biological Products
Aldehydes

High art in synthetic chemistry: the 2010 Nobel Prize in chemistry. Part 2

Karuso, P., 2011, In : Chemistry in Australia. 78, 2, p. 20-24 5 p.

Research output: Contribution to journalArticleResearch

palladium
art

High art in synthetic chemistry: the 2010 Nobel Prize in Chemistry. Part 1

Karuso, P., 2011, Chemistry in Australia, 78, 1, p. 22-25 4 p.

Research output: Contribution to Newspaper/Magazine/WebsiteArticleResearch

Carbon
Palladium
tetraconazole

Three-component mannich-like reaction of 2-aminoimidazole

Shengule, S. R. & Karuso, P., 2011, In : Australian Journal of Chemistry. 64, 12, p. 1617-1620 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Aldehydes
Amines
Water
2-aminoimidazole
sodium carbonate

Ultrafast dynamics of epicocconone, a second generation fluorescent protein stain

Chatterjee, S., Burai, T. N., Karuso, P. & Datta, A., 15 Sep 2011, In : Journal of Physical Chemistry A. 115, 36, p. 10154-10158 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Butylamines
Coloring Agents
adducts
proteins
acetonitrile
2010

High art in synthetic chemistry

Karuso, P., 2010, In : Chemistry in Australia. p. 22-25 4 p.

Research output: Contribution to journalArticleResearch

Tracking of fast moving neuronal vesicles with ageladine A

Bickmeyer, U., Heine, M., Podbielski, I., Münd, D., Köck, M. & Karuso, P., 19 Nov 2010, In : Biochemical and Biophysical Research Communications. 402, 3, p. 489-494 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Neurons
Coloring Agents
Transport Vesicles
Excitatory Postsynaptic Potentials
PC12 Cells
2009

Formation of pigment precursor (+)-1″-methylene-6″-hydroxy2H- furan-5″-one-catechin isomers from (+)-catechin and a degradation product of ascorbic acid in a model wine system

Barril, C., Clark, A. C., Prenzler, P. D., Karuso, P. & Scollary, G. R., 28 Oct 2009, In : Journal of Agricultural and Food Chemistry. 57, 20, p. 9539-9546 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Wine
Catechin
furans
catechin
Pigments

In the limelight: part 2 GFP and the 2008 Nobel Prize in Chemistry

Karuso, P., 2009, In : Chemistry in Australia. 76, 9, p. 26-28 3 p.

Research output: Contribution to journalArticleResearch

In the limelight: part 1 GFP and the 2008 Nobel Prize in Chemistry

Karuso, P., 2009, In : Chemistry in Australia. 76, 8, p. 24-28 5 p.

Research output: Contribution to journalArticleResearch

Rapid isolation of novel FK506 binding proteins from multiple organisms using gDNA and cDNA T7 phage display

Piggott, A. M., Kriegel, A. M., Willows, R. D. & Karuso, P., 1 Oct 2009, In : Bioorganic and Medicinal Chemistry. 17, 19, p. 6841-6850 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tacrolimus Binding Proteins
Bacteriophage T7
Bacteriophages
Complementary DNA
Display devices

The chemical basis for life: the 2009 Nobel prize in chemistry

Karuso, P., 2009, In : Chemistry in Australia. 76, 11, p. 36-39 4 p.

Research output: Contribution to journalArticleResearch

2008

Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion

Cleemann, F. & Karuso, P., 1 Jun 2008, In : Analytical Chemistry. 80, 11, p. 4170-4174 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Assays
Anisotropy
Fluorescence
Substrates
Enzyme inhibition

Mass spectrometric compatibility of Deep Purple and SYPRO Ruby total protein stains for high-throughput proteomics using large-format two-dimensional gel electrophoresis

Nock, C. M., Ball, M. S., White, I. R., Skehel, J. M., Bill, L. & Karuso, P., 2008, In : Rapid Communications in Mass Spectrometry. 22, 6, p. 881-886 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Ruby
Electrophoresis
Coloring Agents
Gels
Throughput

Rapid identification of a protein binding partner for the marine natural product kahalalide F by using reverse chemical proteomics

Piggott, A. M. & Karuso, P., 3 Mar 2008, In : ChemBioChem. 9, 4, p. 524-530 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Real-time fluorescence monitoring of tryptic digestion in proteomics

Karuso, P., Crawford, A. S., Veal, D. A., Scott, G. B. I. & Choi, H. Y., Jan 2008, In : Journal of Proteome Research. 7, 1, p. 361-366 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomics
Proteolysis
Digestion
Fluorescence
Monitoring