• 62 Citations
  • 5 h-Index
20162018
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Personal profile

Biography

Dr. Prita Riana Asih earned her Bachelor of Science degree with first class Honours in Biotechnology at Murdoch University in 2014, for which she was awarded an upper first class and the prize of best student in Biotechnology for her year. Her project was focused on investigating the role of translocator protein (TSPO) ligands on beta amyloid toxicity and steroid production in vitro. On the basis of her Honours work she was invited to NIRS, Japan to work in Dr Makoto Higuchi’s laboratory for a period of 7 months. She investigated these TSPO ligands in a TSPO knockout model developed by Dr Higuchi where she assessed their effects on behaviour.

She then earned her Ph.D. in Molecular Biology from UNSW in February 2019, researching TSPO function in neurodegenerative diseases such as Alzheimer's disease (AD) and Frontotemporal Dementia mouse models under the supervision of Prof Lars Ittner. She graduated with 11 publications, of which 5 being first author.  Prior to Honours completion, she was working as a research assistant at Edith Cowan University, Western Australia from 2009, investigating the role of testosterone in prevention of AD, for which she was leading the clinical trials performed in her home country, Indonesia.

During her PhD, she was working part-time as research assistant at KaRa Institute of Neurological Disease. She is currently working as a research associate at Dementia Research Centre, Macquarie University under the leadership of Dr Arne Ittner.

Education/Academic qualification

Molecular Biology, PhD, The University of New South Wales

17 Mar 201526 Feb 2019

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  • 24 Similar Profiles
Amyloid Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Testosterone Medicine & Life Sciences
Frontotemporal Lobar Degeneration Medicine & Life Sciences
Kynurenine Medicine & Life Sciences
Intermediate Filaments Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
DNA-Binding Proteins Medicine & Life Sciences

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Research Outputs 2016 2018

  • 62 Citations
  • 5 h-Index
  • 6 Article
  • 2 Review article
  • 1 Chapter

Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: a pilot study

Chatterjee, P., Goozee, K., Lim, C. K., James, I., Shen, K., Jacobs, K. R., Sohrabi, H. R., Shah, T., Asih, P. R., Dave, P., ManYan, C., Taddei, K., Lovejoy, D. B., Chung, R., Guillemin, G. J. & Martins, R. N., 1 Dec 2018, In : Scientific Reports. 8, 1, p. 1-10 10 p., 8008.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Kynurenine
Amyloid
Serum
Alzheimer Disease
Social Adjustment

Alzheimer's disease: a journey from amyloid peptides and oxidative stress, to biomarker technologies and disease prevention strategies-gains from AIBL and DIAN cohort studies

Martins, R. N., Villemagne, V., Sohrabi, H. R., Chatterjee, P., Shah, T. M., Verdile, G., Fraser, P., Taddei, K., Gupta, V. B., Rainey-Smith, S. R., Hone, E., Pedrini, S., Lim, W. L., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K. & 17 othersFuller, S. J., Brown, B., Gardener, S. L., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S. M., Barron, A. M., Goozee, K., Wahjoepramono, E. J., Asih, P. R., Doecke, J. D., Salvado, O., Bush, A. I., Rowe, C. C., Gandy, S. E. & Masters, C. L., 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 965-992 28 p.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Amyloid
Alzheimer Disease
Oxidative Stress
Cohort Studies
Biomarkers

Alzheimer’s disease and frontotemporal lobar degeneration: mouse models

Ittner, L. M., Lee, W. S., Stefanoska, K., Asih, P. R. & Ke, Y. D., 1 Jan 2018, NeurodegeneratIve diseases: clinical aspects, molecular genetics and biomarkers. Galimberti, D. & Scarpini, E. (eds.). Second ed. Springer, Springer Nature, p. 187-219 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Frontotemporal Lobar Degeneration
Alzheimer Disease
Genes
Knockout Mice
Transgenic Mice

Association of plasma neurofilament light chain with neocortical amyloid-β load and cognitive performance in cognitively normal elderly participants

Chatterjee, P., Goozee, K., Sohrabi, H. R., Shen, K., Shah, T., Asih, P. R., Dave, P., Manyan, C., Taddei, K., Chung, R., Zetterberg, H., Blennow, K. & Martins, R. N., 1 Jan 2018, In : Journal of Alzheimer's Disease. 63, 2, p. 479-487 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Intermediate Filaments
Amyloid
Light
Alzheimer Disease
Cerebrospinal Fluid

Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load

Goozee, K., Chatterjee, P., James, I., Shen, K., Sohrabi, H. R., Asih, P. R., Dave, P., ManYan, C., Taddei, K., Ayton, S. J., Garg, M., Kwok, J. B., Bush, A. I., Chung, R., Magnussen, J. S. & Martins, R. N., Aug 2018, In : Molecular Psychiatry. 23, 8, p. 1807-1812 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Ferritins
Amyloid
Alzheimer Disease
Area Under Curve
Iron