Projects per year
Search results
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Active
Differential effects of MAPK inhibition on immune activity determine melanoma response
Lim, E., Rizos, H. & Kefford, R.
17/04/17 → …
Project: Research
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Molecular determinants of risk, progression and treatment response in melanoma
Kefford, R., Thompson, J., Hersey, P., Mann, G., Scolyer, R., Hayward, N. & Long, G.
1/01/16 → …
Project: Research
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A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (The METRIC Study)
Kefford, R., Gurney, H., Butala, R. & Archer, L.
12/09/14 → …
Project: Research
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Not started
Speckle-tracking Global Longitudinal Strain (GLS) for Early Detection of Cardiotoxicity from Anticancer Therapy
Brown, M., Al-Zubaidi, K., Gilchrist, J., Kefford, R., Gurney, H. & Poursoltan, P.
Project: Research
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Finished
IPATunity170: A Phase III, Double-Blind, Placebo-Controlled, Randomized Study Of Ipatasertib In Combination With Atezolizumab And Paclitaxel As A Treatment For Patients With Locally Advanced Unresectable Or Metastatic Triple-Negative Breast Cancer
Kefford, R., Chapman, N., Parshionikar, A. & Rajasekharan Nair, A.
22/11/19 → 30/09/24
Project: Other
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IPATunity170: A Phase III, Double-Blind, Placebo-Controlled, Randomized Study Of Ipatasertib In Combination With Atezolizumab And Paclitaxel As A Treatment For Patients With Locally Advanced Unresectable Or Metastatic Triple-Negative Breast Cancer
Kefford, R., Chapman, N., Parshionikar, A. & Rajasekharan Nair, A.
22/11/19 → 30/09/24
Project: Other
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IPATunity170: A Phase III, Double-Blind, Placebo-Controlled, Randomized Study Of Ipatasertib In Combination With Atezolizumab And Paclitaxel As A Treatment For Patients With Locally Advanced Unresectable Or Metastatic Triple-Negative Breast Cancer
Kefford, R., Chapman, N., Parshionikar, A. & Rajasekharan Nair, A.
22/11/19 → 30/09/24
Project: Other
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IPATunity170: A Phase III, Double-Blind, Placebo-Controlled, Randomized Study Of Ipatasertib In Combination With Atezolizumab And Paclitaxel As A Treatment For Patients With Locally Advanced Unresectable Or Metastatic Triple-Negative Breast Cancer
Kefford, R., Chapman, N., Parshionikar, A. & Rajasekharan Nair, A.
22/11/19 → 30/09/24
Project: Other
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A Phase III, Multicenter, Randomized, Open-Label Study Comparing Atezolizumab (Anti-PD-L1 Antibody) in combination with adjuvant Anthracycline/Taxane-based Chemotherapy versus Chemotherapy Alone in patients with operable Triple-Negative Breast Cancer
Sabanathan, D., Kefford, R., Chapman, N. & Butala, R.
5/08/19 → 24/10/23
Project: Other
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A phase III, multicenter, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive, HER2-negative, early breast cancer (New Adjuvant TriAl with Ribociclib [LEE011]: NATALEE)
Sabanathan, D., Kefford, R. & Cunningham, J.
21/03/19 → 20/03/24
Project: Other
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A Phase 3, multicenter, randomized, open-label, active-controlled study of DS-8201a, an anti-HER2-antibody drug conjugate, versus treatment of investigator’s choice for HER2-positive, unresectable and/or metastatic breast cancer subjects pretreated with prior standard of care HER2 therapies, including T-DM1
Kefford, R., Butala, R. & Cunningham, J.
12/03/19 → 25/11/23
Project: Other
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CHARIOT: A phase II study evaluating efficacy and safety of Ipilimumab and Nivolumab with neoadjuvant weekly paclitaxel after anthracycline based chemotherapy in high-risk primary triple negative breast cancer, followed by definitive surgery and one year total duration of Nivolumab
Kefford, R. & Cunningham, J.
6/03/19 → 5/11/20
Project: Other
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AB928CSP0002: A Phase 1/1b Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Breast or Gynecologic Malignancies
Sabanathan, D., Kefford, R., Cunningham, J. & Butala, R.
6/12/18 → 9/04/21
Project: Other
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A Phase 1B/2 study to evaluate safety and anti-tumour activity of AVELUMAB in combination with POLY (ADENOSINE DIPHOSPHATE [ADP]-RIBOSE) POLYMERASE (PARP) inhibitor TALAZOPARIB in patients with locally advance or metastatic solid tumours
Sabanathan, D., Kefford, R., Butala, R. & Cunningham, J.
19/07/18 → 5/01/21
Project: Research
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Centre for Research Excellence in Implementation Science in Oncology (CRE-ISO)
Braithwaite, J., Ward, R., Currow, D., Delaney, G., Kefford, R., Olver, I., Karnon, J., Crowe, P., Liauw, W., Westbrook, J., Meiser, B., Tieman, J., Verspoor, K., Ellis, L., Krishnasamy, M., Ayliff, N., Hawkins, N., Hibbert, P., Farnsworth, R. & Clay-Williams, R.
1/12/17 → 30/11/22
Project: Other
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2017 NSW Premier's Awards for Outstanding Cancer Research - Outstanding Cancer Researcher of the Year
3/11/17 → 3/11/18
Project: Other
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Acquired resistance to PD1 inhibition in melanoma
Rizos, H., Carlino, M., Kefford, R., Zhang, X. D., Menzies, A. M., Long, G., McGuire, H., Yang, J., Scolyer, R. & De St Groth, B. F.
1/01/17 → 31/12/21
Project: Research
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Determinants of response to immune checkpoint inhibitors in melanoma
Rizos, H., Long, G., Menzies, A. M., Yang, J., Carlino, M., Kefford, R., Scolyer, R., MQRES, M., MQRES 3 (International), M. 3. & De St Groth, B. F.
1/01/17 → 31/12/20
Project: Research
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Establishing a centralised biobank for biomedical research
Rizos, H., Kefford, R., Atkin, J., Blair, I., Guillemin, G., Rowe, D., Parakh, S., Sultana, J., Fifita, J. & Tan, V.
1/01/15 → 31/12/15
Project: Research
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Molecular determinants of risk, progression and treatment response in melanoma
1/07/14 → 31/12/15
Project: Research