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20162019

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  • 2017

    3D organization of synthetic and scrambled chromosomes

    Mercy, G., Mozziconacci, J., Scolari, V. F., Yang, K., Zhao, G., Thierry, A., Luo, Y., Mitchell, L. A., Shen, M., Shen, Y., Walker, R., Zhang, W., Wu, Y., Xie, Z., Luo, Z., Cai, Y., Dai, J., Yang, H., Yuan, Y-J., Boeke, J. D. & 3 others, Bader, J. S., Muller, H. & Koszul, R., 10 Mar 2017, In: Science. 355, 6329, 8 p., eaaf4597.

    Research output: Contribution to journalArticlepeer-review

    72 Citations (Scopus)
  • Bug mapping and fitness testing of chemically synthesized chromosome X

    Wu, Y., Li, B-Z., Zhao, M., Mitchell, L. A., Xie, Z-X., Lin, Q-H., Wang, X., Xiao, W-H., Wang, Y., Zhou, X., Liu, H., Li, X., Ding, M-Z., Liu, D., Zhang, L., Liu, B-L., Wu, X-L., Li, F-F., Dong, X-T., Jia, B. & 26 others, Zhang, W-Z., Jiang, G-Z., Liu, Y., Bai, X., Song, T-Q., Chen, Y., Zhou, S-J., Zhu, R-Y., Gao, F., Kuang, Z., Wang, X., Shen, M., Yang, K., Stracquadanio, G., Richardson, S. M., Lin, Y., Wang, L., Walker, R., Luo, Y., Ma, P-S., Yang, H., Cai, Y., Dai, J., Bader, J. S., Boeke, J. D. & Yuan, Y-J., 10 Mar 2017, In: Science. 355, 6329, p. 1-6 8 p., eaaf4706.

    Research output: Contribution to journalArticlepeer-review

    104 Citations (Scopus)
  • Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome

    Shen, Y., Wang, Y., Chen, T., Gao, F., Gong, J., Abramczyk, D., Walker, R., Zhao, H., Chen, S., Liu, W., Luo, Y., Müller, C. A., Paul-Dubois-Taine, A., Alver, B., Stracquadanio, G., Mitchell, L. A., Luo, Z., Fan, Y., Zhou, B., Wen, B. & 20 others, Tan, F., Wang, Y., Zi, J., Xie, Z., Li, B., Yang, K., Richardson, S. M., Jiang, H., French, C. E., Nieduszynski, C. A., Koszul, R., Marston, A. L., Yuan, Y., Wang, J., Bader, J. S., Dai, J., Boeke, J. D., Xu, X., Cai, Y. & Yang, H., 10 Mar 2017, In: Science. 355, 6329, 10 p., eaaf4791.

    Research output: Contribution to journalArticlepeer-review

    91 Citations (Scopus)
  • Engineering the ribosomal DNA in a megabase synthetic chromosome

    Zhang, W., Zhao, G., Luo, Z., Lin, Y., Wang, L., Guo, Y., Wang, A., Jiang, S., Jiang, Q., Gong, J., Wang, Y., Hou, S., Huang, J., Li, T., Qin, Y., Dong, J., Qin, Q., Zhang, J., Zou, X., He, X. & 24 others, Zhao, L., Xiao, Y., Xu, M., Cheng, E., Huang, N., Zhou, T., Shen, Y., Walker, R., Luo, Y., Kuang, Z., Mitchell, L. A., Yang, K., Richardson, S. M., Wu, Y., Li, B-Z., Yuan, Y-J., Yang, H., Lin, J., Chen, G-Q., Wu, Q., Bader, J. S., Cai, Y., Boeke, J. D. & Dai, J., 10 Mar 2017, In: Science. 355, 6329, p. 1-7 8 p., eaaf3981.

    Research output: Contribution to journalArticlepeer-review

    88 Citations (Scopus)
  • "Perfect" designer chromosome v and behavior of a ring derivative

    Xie, Z-X., Li, B. Z., Mitchell, L. A., Wu, Y., Qi, X., Jin, Z., Jia, B., Wang, X., Zeng, B-X., Liu, H-M., Wu, X-L., Feng, Q., Zhang, W-Z., Liu, W., Ding, M-Z., Li, X., Zhao, G-R., Qiao, J-J., Cheng, J-S., Zhao, M. & 73 others, Kuang, Z., Wang, X., Martin, J. A., Stracquadanio, G., Yang, K., Bai, X., Zhao, J., Hu, M-L., Lin, Q-H., Zhang, W-Q., Shen, M-H., Chen, S., Su, W., Wang, E-X., Guo, R., Zhai, F., Guo, X-J., Du, H-X., Zhu, J-Q., Song, T-Q., Dai, J-J., Li, F-F., Jiang, G-Z., Han, S-L., Liu, S-Y., Yu, Z-C., Yang, X-N., Chen, K., Hu, C., Li, D-S., Jia, N., Liu, Y., Wang, L-T., Wang, S., Wei, X-T., Fu, M-Q., Qu, L-M., Xin, S-Y., Liu, T., Tian, K-R., Li, X-N., Zhang, J-H., Song, L-X., Liu, J-G., Lv, J-F., Xu, H., Tao, R., Wang, Y., Zhang, T-T., Deng, Y-X., Wang, Y. R., Li, T., Ye, G-X., Xu, X-R., Xia, Z-B., Zhang, W., Yang, S-L., Liu, Y-L., Ding, W-Q., Liu, Z-N., Zhu, J-Q., Liu, N-Z., Walker, R., Luo, Y., Wang, Y., Shen, Y., Yang, H., Cai, Y., Ma, P-S., Zhang, C-T., Bader, J. S., Boeke, J. D. & Yuan, Y-J., 10 Mar 2017, In: Science. 355, 6329, p. 1-7 8 p., eaaf4704.

    Research output: Contribution to journalArticlepeer-review

    112 Citations (Scopus)
  • Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond

    Mitchell, L. A., Wang, A., Stracquadanio, G., Kuang, Z., Wang, X., Yang, K., Richardson, S., Martin, J. A., Zhao, Y., Walker, R., Luo, Y., Dai, H., Dong, K., Tang, Z., Yang, Y., Cai, Y., Heguy, A., Ueberheide, B., Fenyö, D., Dai, J. & 2 others, Bader, J. S. & Boeke, J. D., 10 Mar 2017, In: Science. 355, 6329, p. 1-11 12 p., eaaf4831.

    Research output: Contribution to journalArticlepeer-review

    107 Citations (Scopus)