Shaokoon Cheng

Associate Professor


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Personal profile


Shaokoon is the program director of the Mechanical Engineering undergraduate program at Macquarie University. His major interest is in translational research, with particular focus on the design and development of biomedical devices and equipment for disease monitoring and diagnosis. Shaokoon has received several competitive national and international research funding and they include 2 NHMRC (lead CI), 2 ARC and a grant from the Food Drug Administration (FDA, USA). Two of his inventions have been awarded patents and they are also the core technologies for a range of biomedical equipment currently being developed in his laboratory. Shaokoon has written more than 90 peer-reviewed publications and is currently leading a team of 7 PhD students and 1 postdoctoral staff to synthesize discoveries obtained from MR imaging, microfluidics, particles fluidization experiments and computational modelling. He has been invited as organizer and invited speaker for more than 10 major international conferences in his field of research. 


Research interests

We are looking for bright and enthusiastic Masters or PhD students with a strong passion to find solutions to improve the quality of lives through engineering. 

BIOMECHANICS and PART (Particles And Respiratory Technology) research group

Current projects:

1. Biomechanics of inhaled drug delivery. 
2. Novel organ-on-chip devices. 
3. Fluid-structure flow interactions in biological systems. 
4. Biomedical devices. 
5. MRI. 
6. 3D printing for biological applications. 


1.  Stereoscopic PIV system for velocity measurement including a micro-PIV system.
2.  High Speed (10KHz) and high resolution (2um) Particle Visualization and Sizing System.
3.  High-Speed Data Acquisition (1-2MHz) and Instrument Control Capabilities.
4.  Tabletop tensile machine (MTS, exceed testing system, E42.503).
5.  Micro-tensile testing machine - SEM (Scanning Electron Microscope) compatible. 
6. Advanced additive manufacturing capabilities to develop optically accessible and highly-complex geometries for any biological organs. 
7.  In house capabilities and facilities to develop organ-on-chip devices.
8.  MR Elastography system. 
9. Optical coherence tomography system (multiple channels) with extended capabilities in flow and elastography measurements. 


1. Design and development of microfluidic devices, organ-on-a-chip platform. 

2. MR Imaging - Phase Contrast MRI, MR Elastography, MR Tagging.

3. Development of optically accessible and physiologically realistic biological organs. 

4. Human and animal MR studies. Ethics applications that involved human patients and diseased animal models.

5. Computational modeling - turbulent and multi-phase flows.

6. Characterization of soft tissue rheological properties. 


My current teaching research interests are in the area of understanding students career information literacy and the development of teaching pedagogies and tools to help improve students' employability and entrepreneurial capabilities. 

Current projects:

1. Enhancing HDR students employability. 

2. Innovative learning tools to enhance product development skills.

3. Embedding effective project-based learning in an engineering curriculum. 


I have a background and a strong passion in product design and development. 

I have developed and convened the following units and the units mark with an asterisk are the units which I am currently teaching and convening. 
1. ENGG150 - Fundamentals of Mechanical and Electronics Engineering
2. MECH203 - Engineering Design 1. (*)
Computer-aided design, a framework for decision-based engineering design, machine design and analysis. (Shigley's Mechanical Engineering Design)
3. MECH204 - Mechanics of Solids. (*)
Modes and mechanics of failure, structural analysis (Hibbeler Mechanics of Materials)
4. MECH303 - Engineering Design 2
5. MECH401 - Product Design and development - Capstone unit. (*)
Product design and development process (Ulrich and Eppinger Product Design and Development)

Community engagement

Education/Academic qualification

Biomedical Engineering, PhD, The University of New South Wales

Mechanical Engineering, BEng, Honours Class 1, University of Sydney

External positions

Member, Australian Rheological Society

Member, Australian and New Zealand Society of Biomechanics

Member, Australian and New Zealand Society of Respiratory Science

Board of Directors, Cerebrospinal Fluid Hydrodynamics

Member, Society of Rheology

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Research Outputs

Effect of an upstream grid on the fluidization of pharmaceutical carrier powders

Elserfy, K., Kourmatzis, A., Chan, H-K., Walenga, R. & Cheng, S., 30 Mar 2020, In : International Journal of Pharmaceutics. 578, p. 1-10 10 p., 119079.

Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Effects of different non-Newtonian models on unsteady blood flow hemodynamics in patient-specific arterial models with in-vivo validation

    Abbasian, M., Shams, M., Valizadeh, Z., Moshfegh, A., Jav, A. & Cheng, S., Apr 2020, In : Computer Methods and Programs in Biomedicine. 186, p. 1-15 15 p., 105185.

    Research output: Contribution to journalArticle

  • 3 Citations (Scopus)

    Non-intrusive high resolution in-vitro measurement of regional drug powder deposition

    Mekonnen, T., Cheng, S. & Kourmatzis, A., 30 May 2020, In : International Journal of Pharmaceutics. 582, p. 1-10 10 p., 119286.

    Research output: Contribution to journalArticle

  • Potential effects of lingual fats on airway flow dynamics and particle deposition

    Ma, B., Kourmatzis, A., Zhao, Y., Yang, R., Chan, H-K., Salehi, F. & Cheng, S., 2020, In : Aerosol Science and Technology. 54, 3, p. 321-331 11 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    The effects of upper airway tissue motion on airflow dynamics

    Zhao, Y., Raco, J., Kourmatzis, A., Diasinos, S., Chan, H-K., Yang, R. & Cheng, S., 23 Jan 2020, In : Journal of Biomechanics. 99, p. 1-6 6 p., 109506.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)


    Travel Award

    Shaokoon Cheng (Recipient), Oct 2011



    • 1 Participating in a conference, workshop, ...

    ASME 2010 International Mechanical Engineering Congress & Exposition

    Shaokoon Cheng (Participant)

    Activity: Participating in or organising an eventParticipating in a conference, workshop, ...