Projects per year
Personal profile
Biography
Dr Shaokoon Cheng's professional practice is in the area of Mechanical Engineering design. His current research work spans aerosol drug delivery, biomechanics and design optimisation using machine learning. Shaokoon pioneered the Mechanical Engineering undergraduate program, and more recently, the Master's in Mechanical Engineering program in MQ. His scientific contributions have led to over 140 peer-reviewed publications, six patents, and numerous competitive research funding as the chief investigator, including international grants from the U.S. Food and Drug Administration. As a founding director and chief technology officer of ASKSCIENTIA, Shaokoon also leads the translation of cutting-edge research into manufacturable and scalable technologies in aerosol diagnostics and biomedical devices. He currently leads a team of 9 higher degree research students, 2 postdocs, and has successfully supervised 18 HDR students to completion. He offers a highly supportive and responsive mentorship, that provides training from fundamental research, ways to derive innovation, to ultimately their translation.
Research interests
We are looking for bright and enthusiastic Masters or PhD students with a strong passion to find solutions to improve the quality of lives through engineering.
BIOMECHANICS and PART (Particles And Respiratory Technology) research group
Current projects:
1. Biomechanics of inhaled drug delivery.
2. Novel organ-on-chip devices.
3. Mechanical design and machine learning.
4. Design and development of real-time sensors.
5. Experimental characterisation of aerosol flow and deposition.
6. 3D printing for biological applications.
7. Mechanical design for thermal management systems.
8. Structural and mechanical design of drone platforms.
Equipment:
1. Stereoscopic PIV system for velocity measurement including a micro-PIV system.
2. High Speed (10KHz) and high resolution (2um) Particle Visualization and Sizing System.
3. High-Speed Data Acquisition (1-2MHz) and Instrument Control Capabilities.
4. Tabletop tensile machine (MTS, exceed testing system, E42.503).
5. Micro-tensile testing machine - SEM (Scanning Electron Microscope) compatible.
6. Advanced additive manufacturing capabilities to develop optically accessible and highly-complex geometries for any biological organs.
7. In house capabilities and facilities to develop organ-on-chip devices.
8. MR Elastography system.
9. Optical coherence tomography system (multiple channels) with extended capabilities in flow and elastography measurements.
Teaching Research
My current teaching research interests are in the area of understanding students career information literacy and the development of teaching pedagogies and tools to help improve students' employability and entrepreneurial capabilities.
Education/Academic qualification
Biomedical Engineering, PhD, The University of New South Wales
Mechanical Engineering, BEng, Honours Class 1, University of Sydney
External positions
Member, Australian Rheological Society
Member, Australian and New Zealand Society of Biomechanics
Member, Australian and New Zealand Society of Respiratory Science
Board of Directors, Cerebrospinal Fluid Hydrodynamics
Member, Society of Rheology
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Collaborations and top research areas from the last five years
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LP24 (Usyd led): Real-time correlation of aerosol flow and surface deposition
Kourmatzis, A. (Chief Investigator), Cheng, S. (Primary Chief Investigator), Chan, H.-K. (Chief Investigator) & Farina, D. (Partner Investigator)
23/04/25 → 1/06/28
Project: Research
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Determinants of Structural Morphology Across Scales
Cheng, S. (Primary Chief Investigator)
1/01/25 → …
Project: Research
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Data-Driven Optimisation in Aerosol Drug Delivery
Cheng, S. (Primary Chief Investigator)
1/11/24 → …
Project: Research
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Imaging and Optical Diagnostic Instrumentation for Advanced Aerosol Characterisation
Cheng, S. (Primary Chief Investigator), Kourtmatzis, A. (Primary Chief Investigator) & Chan, K. (Primary Chief Investigator)
1/08/23 → …
Project: Research
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Artificial Intelligence for Performance-Optimised Design in Energy and Aerodynamics
Cheng, S. (Primary Chief Investigator) & Lee, A. (Primary Chief Investigator)
1/06/23 → …
Project: Research
Research Outputs
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Age-related anatomical variations and the impact of adenoid hypertrophy on nasal airflow in Asian children
Hu, Z., Chen, J., Zhang, Y., Wang, Y., Zhao, Y., Zheng, G., Cheng, S., Inthavong, K. & Dong, J., 2025, In: European Journal of Mechanics - B/Fluids. 114, p. 1-15 15 p., 204321.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure) -
A new method for simultaneous measurement of droplet or particle surface area and velocity
Milton-McGurk, L., Cheng, S., Farina, D., Chan, H.-K. & Kourmatzis, A., Jan 2026, In: Optics and Lasers in Engineering. 196, p. 1-17 17 p., 109415.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A preliminary numerical study of nasal air conditioning following maxillary sinus stent implantation
Ma, R. P., Li, Z. H., Ren, H. X., Yang, F. L., Wang, Y. S., Zhang, L. Y., Zheng, G. X., Zhu, K., Cheng, S., Zhang, Y. & Dong, J. L., 31 Jul 2025, (E-pub ahead of print) In: IEEE Transactions on Biomedical Engineering.Research output: Contribution to journal › Article › peer-review
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Characterizing particle deposition in physiologically realistic airways and the influence of BMI: a combined experimental and computational study
Cai, X., Milton-McGurk, L., Ma, Z., Chan, H.-K., Kourtmatzis, A. & Cheng, S., Jan 2026, In: Journal of Drug Delivery Science and Technology. 115, Part 2, p. 1-13 13 p., 107810.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Characterizing the time dependent deposition of particles in a channel flow using optical coherence tomography
Mekonnen, T. T., Cheng, S., Chan, H.-K. & Kourmatzis, A., Nov 2025, In: Powder Technology. 465, p. 1-10 10 p., 121389.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure)