• 291 Citations
  • 9 h-Index

Research output per year

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Personal profile


Dr Shelley Forrest is a group leader at the Dementia Research Centre in the Department of Biomedical Sciences, Faculty of Medicine and Health Sciences at Macquarie University. She completed her PhD in Neuroscience from The University of Sydney in 2013 and commenced postdoctoral training in the Discipline of Pathology, The University of Sydney. During this time, she has acquired a deep knowledge of the cellular abnormalities characteristic of frontotemporal dementia and related disorders, ageing and a range of neurodegenerative diseases. She has established national and international collaborations, and has been a member of international consortia that validated a novel age-related tauopathy. In 2020, Shelley joined the Dementia Research Centre as the Neuropathology group leader to facilitate the development of a neuropathology program combining human neurodegenerative diseases and transgenic models of dementia.

Research interests

Shelley’s research focuses on the neuropathology and disease mechanisms underlying frontotemporal dementia, ageing and a range of neurodegenerative disorders. In particular, her work involves the investigation of protein abnormalities and cell types affected to determine the selective regional and cellular vulnerability in these disorders, and associated clinicopathological correlations. To address these questions, Shelley uses a combination of histology, immunohistochemistry and quantitative neuropathology in well-characterised human brain tissue samples and transgenic animal models of dementia.

Education/Academic qualification

Higher Education, Graduate Certificate, University of Sydney

Neuroanatomy and Neuroscience, PhD, University of Sydney

Anatomy and Pathology, BSc (Hons), The University of New South Wales

External positions

Honorary Lecturer, University of Sydney

1 Feb 202031 Dec 2021

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Research Outputs

  • 291 Citations
  • 9 h-Index
  • 18 Article
  • 1 Review article

A practical approach to differentiate the frontotemporal tauopathy subtypes

Forrest, S., Halliday, G., Sizemova, A., van Roijen, M., McGinley, C., Bright, F., Kapur, M., McGeachie, A., McCann, H., Shepherd, C., Tan, R., Affleck, A., Huang, Y. & Kril, J., 2020, (Accepted/In press) In : Journal of Neuropathology and Experimental Neurology.

Research output: Contribution to journalArticle

  • Are mutations in MAPT associated with GGT type III?

    Forrest, S. L., Halliday, G. M., Shepherd, C. E., Kwok, J. B., Hallupp, M. & Kril, J. J., 16 Oct 2019, In : Neuropathology and Applied Neurobiology. 46, 4, p. 406-409 4 p.

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Cellular and regional vulnerability in frontotemporal tauopathies

    Forrest, S. L., Kril, J. J. & Halliday, G. M., Nov 2019, In : Acta Neuropathologica. 138, 5, p. 705-727 23 p.

    Research output: Contribution to journalReview article

  • 5 Citations (Scopus)

    Chronic traumatic encephalopathy (CTE) is absent from a European community-based aging cohort while cortical aging-related tau astrogliopathy (ARTAG) is highly prevalent

    Forrest, S. L., Kril, J. J., Wagner, S., Hönigschnabl, S., Reiner, A., Fischer, P. & Kovacs, G. G., 1 May 2019, In : Journal of Neuropathology and Experimental Neurology. 78, 5, p. 398-405 8 p.

    Research output: Contribution to journalArticle

  • 6 Citations (Scopus)

    Coexisting Lewy body disease and clinical parkinsonism in frontotemporal lobar degeneration

    Forrest, S. L., Crockford, D. R., Sizemova, A., McCann, H., Shepherd, C. E., McGeachie, A. B., Affleck, A. J., Carew-Jones, F., Bartley, L., Kwok, J. B., Kim, W. S., Jary, E., Tan, R. H., McGinley, C. V., Piguet, O., Hodges, J. R., Kril, J. J. & Halliday, G. M., 21 May 2019, In : Neurology. 92, 21, p. e2472-e2482 11 p.

    Research output: Contribution to journalArticle

  • 4 Citations (Scopus)