Research output per year
Research output per year
Personal profile
Biography
Dr Shelley Forrest is a group leader at the Dementia Research Centre in the Department of Biomedical Sciences, Faculty of Medicine and Health Sciences at Macquarie University. She completed her PhD in Neuroscience from The University of Sydney in 2013 and commenced postdoctoral training in the Discipline of Pathology, The University of Sydney. During this time, she has acquired a deep knowledge of the cellular abnormalities characteristic of frontotemporal dementia and related disorders, ageing and a range of neurodegenerative diseases. She has established national and international collaborations, and has been a member of international consortia that validated a novel age-related tauopathy. In 2020, Shelley joined the Dementia Research Centre as the Neuropathology group leader to facilitate the development of a neuropathology program combining human neurodegenerative diseases and transgenic models of dementia.
Research interests
Shelley’s research focuses on the neuropathology and disease mechanisms underlying frontotemporal dementia, ageing and a range of neurodegenerative disorders. In particular, her work involves the investigation of protein abnormalities and cell types affected to determine the selective regional and cellular vulnerability in these disorders, and associated clinicopathological correlations. To address these questions, Shelley uses a combination of histology, immunohistochemistry and quantitative neuropathology in well-characterised human brain tissue samples and transgenic animal models of dementia.
Education/Academic qualification
Higher Education, Graduate Certificate, University of Sydney
Award Date: 14 Nov 2019
Neuroanatomy and Neuroscience, PhD, University of Sydney
Award Date: 12 Dec 2013
Anatomy and Pathology, BSc (Hons), The University of New South Wales
Award Date: 10 Dec 2007
External positions
Honorary Lecturer, University of Sydney
1 Feb 2020 → 31 Dec 2021
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Association between globular glial tauopathies and frontotemporal dementia-expanding the spectrum of gliocentric disorders: a review
Forrest, S. L., Kril, J. J. & Koavcs, G. G., 1 Aug 2021, In: JAMA Neurology. 78, 8, p. 1004-1014 11 p.Research output: Contribution to journal › Review article › peer-review
4 Citations (Scopus) -
Coexisting Lewy body disease and clinical parkinsonism in amyotrophic lateral sclerosis
Forrest, S. L., Kim, J. H., De Sousa, C., Cheong, R., Crockford, D. R., Sheedy, D., Stevens, J., McCrossin, T., Tan, R. H., McCann, H., Shepherd, C. E., Rowe, D. B., Kiernan, M. C., Halliday, G. M. & Kril, J. J., Jul 2021, In: European Journal of Neurology. 28, 7, p. 2192-2199 8 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Globular glial tauopathy with a mutation in MAPT and unusual TDP-43 proteinopathy in a patient with behavioural-variant frontotemporal dementia
Forrest, S. L., Shepherd, C. E., McCann, H., Kwok, J. B., Halliday, G. M. & Kril, J. J., May 2021, In: Acta Neuropathologica. 141, 5, p. 791-794 4 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Neurodegenerative proteinopathies associated with neuroinfections
Danics, K., Forrest, S. L., Kapas, I., Erber, I., Schmid, S., Törő, K., Majtenyi, K. & Kovacs, G., Oct 2021, In: Journal of Neural Transmission. 128, 10, p. 1551-1566 16 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
A practical approach to differentiate the frontotemporal tauopathy subtypes
Forrest, S. L., Halliday, G. M., Sizemova, A., van Roijen, M., McGinley, C. V., Bright, F., Kapur, M., McGeachie, A. B., McCann, H., Shepherd, C. E., Tan, R. H., Affleck, A. J., Huang, Y. & Kril, J. J., Oct 2020, In: Journal of Neuropathology and Experimental Neurology. 79, 10, p. 1122-1126 5 p.Research output: Contribution to journal › Article › peer-review