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Shu Yang

Dr

 https://orcid.org/0000-0002-4847-9263
  • 644 Citations
  • 13 h-Index
20072020
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Fingerprint Dive into the research topics where Shu Yang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Amyotrophic Lateral Sclerosis Medicine & Life Sciences
Mutation Medicine & Life Sciences
Cyclins Medicine & Life Sciences
DNA-Binding Proteins Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences
Genes Chemical Compounds
Frontotemporal Dementia Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2020

Revealing the role of protein clearance pathways in sporadic ALS

Chung, R., Lee, A., Rayner, S. & Yang, S.

1/05/19 → 30/04/20

Project: Research

Macquarie University Centre for Motor Neuron Disease Research

Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, C., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, M., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.

1/01/17 → 31/12/19

Project: Research

Advanced protein quantification capability

Walker, A., Lee, A., Connor, M., Atkin, J., Lim, C., Baker, M., Rizos, H., Phillips, J., Yang, S. & Blair, I.

1/01/17 → …

Project: Research

Generation of a stem cell model for the validation of novel amyotrophic lateral sclerosis (ALS) candidate genes.

Yang, S. & Blair, I.

1/01/17 → …

Project: Research

MNDRIA_Grant: Assessing the pathogenic role of novel MND candidate genes

Yang, S.

26/06/18 → 29/09/18

Project: Other

Research Outputs 2007 2019

  • 644 Citations
  • 13 h-Index
  • 21 Article
  • 2 Review article
  • 1 Meeting abstract

Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming

Bax, M., Balez, R., Muñoz, S. S., Do-Ha, D., Stevens, C. H., Berg, T., Cabral-da-Silva, M. C., Engel, M., Nicholson, G., Yang, S., Blair, I. P. & Ooi, L., 1 Oct 2019, In : Stem Cell Research. 40, p. 1-4 4 p., 101530.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
File
Induced Pluripotent Stem Cells
Cyclins
Amyotrophic Lateral Sclerosis
Fibroblasts
Cell Line

DNA nanoclew templated spherical nucleic acids for siRNA delivery

Ruan, W., Zheng, M., An, Y., Liu, Y., Lovejoy, D., Hao, M., Zou, Y., Lee, A., Yang, S., Lu, Y., Morsch, M., Chung, R. & Shi, B., 14 Apr 2018, In : Chemical Engineering Communications. 54, p. 3609-3612 4 p.

Research output: Contribution to journal › Article › Research › peer-review

Nucleic acids
Nucleic Acids
Small Interfering RNA
DNA
Ribonuclease III

ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis

Parakh, S., Jagaraj, C. J., Vidal, M., Ragagnin, A. M. G., Perri, E. R., Konopka, A., Toth, R. P., Galper, J., Blair, I. P., Thomas, C. J., Walker, A. K., Yang, S., Spencer, D. M. & Atkin, J. D., 15 Apr 2018, In : Human molecular genetics. 27, 8, p. 1311-1331 21 p.

Research output: Contribution to journal › Article › Research › peer-review

Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum Stress
Pathology
Apoptosis
DNA-Binding Proteins

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D. & 2 othersMolloy, M. P. & Chung, R. S., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.

Research output: Contribution to journal › Article › Research › peer-review

Cyclins
Ubiquitination
Autophagy
Mutation
Genes

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex

Lee, A., Rayner, S. L., De Luca, A., Gwee, S. S. L., Morsch, M., Sundaramoorthy, V., Shahheydari, H., Ragagnin, A., Shi, B., Yang, S., Williams, K. L., Don, E. K., Walker, A. K., Zhang, K. Y., Yerbury, J. J., Cole, N. J., Atkin, J. D., Blair, I. P., Molloy, M. P. & Chung, R. S., 2017, In : Open Biology. 7, 10, p. 1-11 11 p., 170058.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
File
Casein Kinase II
Phosphorylation
Cyclins
Ubiquitin-Protein Ligases
Ubiquitination