Projects per year
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- 12 Similar Profiles
Amyotrophic Lateral Sclerosis
Medicine & Life Sciences
Mutation
Medicine & Life Sciences
DNA-Binding Proteins
Medicine & Life Sciences
Cyclins
Medicine & Life Sciences
RNA-Binding Proteins
Medicine & Life Sciences
Genes
Chemical Compounds
Frontotemporal Dementia
Medicine & Life Sciences
Ubiquitination
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2020
Revealing the role of protein clearance pathways in sporadic ALS
Chung, R., Lee, A., Rayner, S. & Yang, S.
1/05/19 → 30/04/20
Project: Research
Advanced protein quantification capability
Walker, A., Lee, A., Connor, M., Atkin, J., Lim, C., Baker, M., Rizos, H., Phillips, J., Yang, S. & Blair, I.
1/01/17 → …
Project: Research
Macquarie University Centre for Motor Neuron Disease Research
Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, C., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, T., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.
1/01/17 → 31/12/19
Project: Research
MNDRIA_Grant: Assessing the pathogenic role of novel MND candidate genes
26/06/18 → 29/09/18
Project: Other
Research Outputs 2007 2018
DNA nanoclew templated spherical nucleic acids for siRNA delivery
Ruan, W., Zheng, M., An, Y., Liu, Y., Lovejoy, D., Hao, M., Zou, Y., Lee, A., Yang, S., Lu, Y., Morsch, M., Chung, R. & Shi, B., 14 Apr 2018, In : Chemical Engineering Communications. 54, p. 3609-3612 4 p.Research output: Contribution to journal › Article › Research › peer-review
Nucleic acids
Nucleic Acids
Small Interfering RNA
DNA
Ribonuclease III
ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis
Parakh, S., Jagaraj, C. J., Vidal, M., Ragagnin, A. M. G., Perri, E. R., Konopka, A., Toth, R. P., Galper, J., Blair, I. P., Thomas, C. J., Walker, A. K., Yang, S., Spencer, D. M. & Atkin, J. D., 15 Apr 2018, In : Human molecular genetics. 27, 8, p. 1311-1331 21 p.Research output: Contribution to journal › Article › Research › peer-review
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum Stress
Pathology
Apoptosis
DNA-Binding Proteins
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy
Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D. & 2 others, Jan 2018, In : Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.Research output: Contribution to journal › Article › Research › peer-review
Cyclins
Ubiquitination
Autophagy
Mutation
Genes
Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex
Lee, A., Rayner, S. L., De Luca, A., Gwee, S. S. L., Morsch, M., Sundaramoorthy, V., Shahheydari, H., Ragagnin, A., Shi, B., Yang, S., Williams, K. L., Don, E. K., Walker, A. K., Zhang, K. Y., Yerbury, J. J., Cole, N. J., Atkin, J. D., Blair, I. P., Molloy, M. P. & Chung, R. S., 2017, In : Open Biology. 7, 10, p. 1-11 11 p., 170058.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Casein Kinase II
Phosphorylation
Cyclins
Ubiquitin-Protein Ligases
Ubiquitination
Cyclin F: a component of an E3 ubiquitin ligase complex with roles in neurodegeneration and cancer
Galper, J., Rayner, S. L., Hogan, A. L., Fifita, J. A., Lee, A., Chung, R. S., Blair, I. P. & Yang, S., 1 Aug 2017, In : International Journal of Biochemistry and Cell Biology. 89, p. 216-220 5 p.Research output: Contribution to journal › Article › Research › peer-review
Cyclins
Ubiquitin-Protein Ligases
Cell Cycle Checkpoints
Frontotemporal Dementia
Neoplasms