Research Output per year
Research Output per year
Personal profile
Biography
Sina received his master’s degree in neuropharmacology from the college of Pharmacy, Yeungnam University in South Korea, where he studied the role of neurotrophic factors in Parkinson’s and Alzheimer’s disease. During 2014 ‐ 2017, he worked as a research assistant and lab manager in the College of Pharmacy, Yeungnam University.
Currently, he is a PhD candidate in the Centre for Motor Neuron Disease, Faculty of Medicine and Health Science, Macquarie University. In his current research, he has identified novel proteins as new therapeutic targets for MND in both cells and in vivo models (zebrafish, rodents, and C. elegans). In 2018, he was awarded Federation of Europian Neuroscience Societies and International Brain Organization's (FENS-IBRO) young investigators training grant to join to the Leibniz Institute for Molecular Pharmacology (FMP) in Berlin, Germany, where he trained to use Caenorhabditis elegans (C. elegans) as a model to study ALS, under the supervision of Prof. Dr. Janine Kirstein.
Teaching
- MEDI3301; Clinical Neurosciences, Department of Clinical Medicine, Macquarie University, Australia
-MEDI304; Advanced Clinical Science, Department of Biomedical Sciences, Macquarie University, Australia
- CBMS 201/ CBMS 602; Biochemistry and Cell Biology, Department of Chemistry and Biomolecular Sciences, Macquarie University, Australia
- Advanced Pharmacology, College of Pharmacy, Yeungnam University, South Korea, 2014-2017
Research interests
Cellular and Molecular Neurobiology; Neurodegenerative Disease; Amyotrophic Lateral sclerosis; Motor Neuron Disease
Community engagement
- HDR students representative at Macquarie University MND centre executive committee; 2019- present
- Member of Macquarie University MND centre social media team; 2020- present
- Atkin's lab representative at the Faculty of Medicine and Health Sciences Lab users meeting; 2018- present
Education/Academic qualification
Neuropharmacology, Master's degree, Yeungnam University
30 Sep 2013 → 22 Feb 2016
External positions
Research/Teaching assistant, Yeungnam University
2014 → 2017Fingerprint
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Research Outputs
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Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations
Konopka, A., Whelan, D. R., Jamali, M. S., Perri, E., Shahheydari, H., Toth, R. P., Parakh, S., Robinson, T., Cheong, A., Mehta, P., Vidal, M., Ragagnin, A. M. G., Khizhnyak, I., Jagaraj, C. J., Galper, J., Grima, N., Deva, A., Shadfar, S., Nicholson, G. A., Yang, S. & 6 others, , 9 Sep 2020, In : Molecular Neurodegeneration. 15, 1, p. 1-28 28 p., 51.Research output: Contribution to journal › Article
Open AccessFile4 Downloads (Pure) -
The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish models
Parakh, S., Shadfar, S., Perri, E. R., Ragagnin, A. M. G., Piattoni, C. V., Fogolín, M. B., Yuan, K. C., Shahheydari, H., Don, E. K., Thomas, C. J., Hong, Y., Comini, M. A., Laird, A. S., Spencer, D. M. & Atkin, J. D., 22 May 2020, In : iScience. 23, 5, p. 1-27 44 p., 101097.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Identifying novel roles for Protein Disulfide Isomerase (PDI) in Amyotrophic Lateral Sclerosis (ALS)
Shadfar, S., Shahheydari, H., Parakh, S., Laird, A. S. & Atkin, J., 2019, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 20, Supplement 1, p. 176-177 2 p., IVV-27.Research output: Contribution to journal › Meeting abstract
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Motor neuron susceptibility in ALS/FTD
Ragagnin, A. M. G., Shadfar, S., Vidal, M., Jamali, M. S. & Atkin, J. D., 27 Jun 2019, In : Frontiers in Neuroscience. 13, JUN, p. 1-37 37 p., 532.Research output: Contribution to journal › Review article
Open AccessFile24 Citations (Scopus)10 Downloads (Pure) -
Enhanced neuroinflammatory responses after systemic LPS injection in IL-32β transgenic mice
Neupane, S., Srivastav, S., Bhurtel, S., Katila, N., Shadfar, S., Park, P-H., Hong, J. T. & Choi, D-Y., Dec 2018, In : Journal of Chemical Neuroanatomy. 94, p. 173-182 10 p.Research output: Contribution to journal › Article
3 Citations (Scopus)
Prizes
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Macquarie University Postgraduate Research Fund (PGRF)
Sina Shadfar (Recipient), 2018
Prize: Other distinction
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