Projects per year
Personal profile
Biography
I am early career researcher working at the MND Centre in Macquarie University. I have a strong focus working on MND disease and to identify and characterize the molecular origins of MND/ALS so to develop future therapeutic targets.
Education/Academic qualification
Neuroscience, PhD, Macquarie University
Biotechnology and Bioinfromatics, Masters, La Trobe University, Bundoora Victoria
Biotechnology, Bachelor's, Bangalore University
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Projects
- 2 Finished
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Macquarie University Centre for Motor Neuron Disease Research
Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, E., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A. K., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, M., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.
1/01/17 → 31/12/19
Project: Research
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Establishing a centralised biobank for biomedical research
Rizos, H., Kefford, R., Atkin, J., Blair, I., Guillemin, G., Rowe, D., Parakh, S., Sultana, J., Fifita, J. & Tan, V.
1/01/15 → 31/12/15
Project: Research
Research Outputs
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Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
Halloran, M., Ragagnin, A. M. G., Vidal, M., Parakh, S., Yang, S., Heng, B., Grima, N., Shahheydari, H., Soo, K-Y., Blair, I., Guillemin, G. J., Sundaramoorthy, V. & Atkin, J. D., Oct 2020, In : Cellular and Molecular Life Sciences. 77, 19, p. 3859-3873 15 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations
Konopka, A., Whelan, D. R., Jamali, M. S., Perri, E., Shahheydari, H., Toth, R. P., Parakh, S., Robinson, T., Cheong, A., Mehta, P., Vidal, M., Ragagnin, A. M. G., Khizhnyak, I., Jagaraj, C. J., Galper, J., Grima, N., Deva, A., Shadfar, S., Nicholson, G. A., Yang, S. & 6 others, , 9 Sep 2020, In : Molecular Neurodegeneration. 15, 1, p. 1-28 28 p., 51.Research output: Contribution to journal › Article
Open AccessFile4 Downloads (Pure) -
The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosis
Perri, E. R., Parakh, S., Vidal, M., Mehta, P., Ma, Y., Walker, A. K. & Atkin, J. D., Sep 2020, In : Journal of Molecular Neuroscience. 70, 9, p. 1357-1368 12 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish models
Parakh, S., Shadfar, S., Perri, E. R., Ragagnin, A. M. G., Piattoni, C. V., Fogolín, M. B., Yuan, K. C., Shahheydari, H., Don, E. K., Thomas, C. J., Hong, Y., Comini, M. A., Laird, A. S., Spencer, D. M. & Atkin, J. D., 22 May 2020, In : iScience. 23, 5, p. 1-27 44 p., 101097.Research output: Contribution to journal › Article
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Identifying novel roles for Protein Disulfide Isomerase (PDI) in Amyotrophic Lateral Sclerosis (ALS)
Shadfar, S., Shahheydari, H., Parakh, S., Laird, A. S. & Atkin, J., 2019, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 20, Supplement 1, p. 176-177 2 p., IVV-27.Research output: Contribution to journal › Meeting abstract