Projects per year
Personal profile
Biography
Professor Graham (MBBS, MS, PhD, FRANZCO) is Head of Ophthalmology and Visual Science at Macquarie University Faculty of Medicine, and a Visiting Professor at the Save Sight Institute, Sydney University. He practices as a glaucoma subspecialist, with a special interest in early diagnosis and electrophysiology. His research involves mechanisms of optic nerve damage, including vascular, molecular and genetic factors and new imaging techniques for structural analysis and dynamic retinal vascular changes. His research team is studying neurodegenerative pathways with a view to developing neuroprotective therapies for glaucoma and multiple sclerosis.
External positions
Visiting Professor, University of Sydney
2008 → …
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Collaborations and top research areas from the last five years
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CTCS 22 (Flinders led): A randomised controlled trial in genetically at-risk individuals to determine the efficacy of early laser treatment in preventing glaucomatous vision loss
Craig, J. (Chief Investigator), Hewitt, A. W. (Chief Investigator), Graham, S. L. (Primary Chief Investigator), Casson, R. (Chief Investigator), Souzeau, E. (Chief Investigator), Siggs, O. M. (Chief Investigator), McGregor, S. (Chief Investigator), Pesudovs, K. (Chief Investigator), Si, L. (Chief Investigator), Morton, E. (Chief Investigator), Landers, J. (Associate Investigator), Agar, A. (Associate Investigator), White, A. (Associate Investigator), Thomson, D. (Associate Investigator), Kizilersu, A. (Associate Investigator) & Savarirayan, R. (Associate Investigator)
5/05/24 → 4/05/28
Project: Research
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MRFF (Flinders led): Implementing a novel model of management for glaucoma using polygenic risk profiling
Craig, J. (Chief Investigator), Hewitt, A. W. (Chief Investigator), Siggs, O. M. (Chief Investigator), Souzeau, E. (Chief Investigator), Kitson, A. (Chief Investigator), Harvey, G. (Chief Investigator), Gharahkhani, P. (Chief Investigator), Karnon, J. (Chief Investigator), Mackey, D. (Chief Investigator), Healey, P. (Chief Investigator), White, A. J. R. (Chief Investigator), Lee, S. (Chief Investigator), Casson, R. (Chief Investigator), Graham, S. L. (Primary Chief Investigator), Pesudovs, K. (Chief Investigator), Kaub, P. (Associate Investigator), Landers, J. (Associate Investigator), Yapp, M. (Associate Investigator), Burdon, K. P. (Associate Investigator), Kizilersu, A. (Associate Investigator), Agar, A. (Associate Investigator), MacGregor, S. (Associate Investigator), Keay, L. (Associate Investigator), Hassall, M. (Associate Investigator) & Lawlor, M. (Associate Investigator)
1/06/23 → 31/05/27
Project: Research
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Let there be light- Modified Serpin as a Dual Function Therapeutic Agent in Glaucoma
Gupta, V. (Primary Chief Investigator), Graham, S. L. (Chief Investigator), Rajala, R. V. S. (Chief Investigator), Gupta, V. B. (Chief Investigator), Komaromy, A. (Chief Investigator), Mirzaei, M. (Chief Investigator) & Chitranshi, N. (Associate Investigator)
1/05/23 → 30/04/27
Project: Research
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Screening the eyes for early diagnosis of Alzheimer's disease
Graham, S. L. (Primary Chief Investigator) & Golzan, M. (Chief Investigator)
1/07/17 → …
Project: Research
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Quantifing retinal vascular changes in obstructive sleep apnea as a means of monitoring disease progression and efficacy of treatment
Fraser, C. (Primary Chief Investigator), Graham, S. L. (Associate Investigator), Farah, C. (Associate Investigator) & Tong, J. (Associate Investigator)
1/01/17 → …
Project: Research
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A multitrait polygenic risk score for open-angle glaucoma stratifies risk of pigmentary glaucoma in pigment dispersion syndrome
Kolovos, A., Qassim, A., Marshall, H. N., Nguyen, T. T., Schmidt, J., Hassall, M. M., Tang, V., Maxwell, G., Landers, J., Mills, R., Lake, S., Graham, S. L., Schulz, A., Galanopoulos, A., Casson, R. J., Goldberg, I., Coote, M., Best, S., Lusthaus, J. & Healey, P. R. & 12 others, , 1 Mar 2026, In: Ophthalmology Glaucoma. 9, 2, p. 193-201 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus) -
Early retinal UCHL1 dysregulation coupled with synaptic loss reflects Alzheimer's disease severity
Rentsendorj, A., Vit, J.-P., Hutton, A., Koronyo, Y., Shahin, S., Robinson, E., Barron, E., Rodriguez, A., Jallow, O., Sheyn, J., Gaire, B. P., Subedi, L., Davis, M. R., Gnanabharathi, B., Ljubimov, A. V., Graham, S. L., Gupta, V. K., Mirzaei, M., Hawes, D. & Silm, K. & 6 others, , 29 Aug 2026, (E-pub ahead of print) In: Advanced Science. 34 p., e00020.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina
Gaire, B. P., Koronyo, Y., Vit, J.-P., Hutton, A., Subedi, L., Fuchs, D.-T., Swerdlow, N., Rentsendorj, A., Shahin, S., Martinon, D., Robinson, E., Ljubimov, A. V., Schneider, J. A., Schneider, L. S., Hawes, D., Graham, S. L., Gupta, V. K., Mirzaei, M., Black, K. L. & Meyer, J. G. & 3 others, , 22 Jan 2026, In: Nature Communications. 17, 1, p. 1-24 24 p., 771.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Link opens in a new tab Citations (Scopus)3 Downloads (Pure) -
Impact of continuous positive airway pressure treatment on retinal vasculature in obstructive sleep apnea: a 7-year follow-up
Rodrigues, D., Schulz, A. M., Britton, A., Wong, B., Tong, J., Farah, C. S., Graham, S. L. & Fraser, C. L., 3 Aug 2026, In: Investigative Ophthalmology and Visual Science. 67, 10, p. 1-8 8 p., 7.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Invisible threats of microplastics induced toxicity: oxidative and inflammatory pathways in the CNS and retina
Shenoy, A., Eva, T. A., Palanivel, V., Salkar, A., Gupta, V. B., Chitranshi, N., Graham, S. L., Gupta, V. & Basavarajappa, D., 2026, Brain Energy Metabolism in Alzheimers Disease: Part A. Academic Press Inc., p. 25-47 (International Review of Neurobiology; vol. 186).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review