20002020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Outputs

2011

Tropomyosin isoforms and reagents

Schevzov, G., Whittaker, S. P., Fath, T., Lin, J. J-C. & Gunning, P. W., 1 Jan 2011, In : Bioarchitecture. 1, 4, p. 135-164 30 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Tropomyosins induce neurite formation in B35 neuroblastoma cells and control neurite branching

Curthoys, N., Freittag, H., Connor, A., Desouza, M., Hardeman, E., Gunning, P., Schevzov, G. & Fath, T., 1 Jan 2011, In : Molecular Biology of the Cell. 22, 24, 1 p., 1507.

Research output: Contribution to journalMeeting abstract

2010

New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2

Fath, T., Agnes Chan, Y. K., Vrhovski, B., Clarke, H., Curthoys, N., Hook, J., Lemckert, F., Schevzov, G., Tam, P., Watson, C. M., Khoo, P. L. & Gunning, P., 1 Jul 2010, In : European Journal of Cell Biology. 89, 7, p. 489-498 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2009

A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau

Brandt, R., Gergou, A., Wacker, I., Fath, T. & Hutter, H., 1 Jan 2009, In : Neurobiology of Aging. 30, 1, p. 22-33 12 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Intracellular structural compartments, disease and tropomyosins

Schevzov, G., Fath, T. & Gunning, P. W., 1 Dec 2009, In : Current Topics in Pharmacology. 13, 2, p. 1-15 15 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Primary support cultures of hippocampal and substantia nigra neurons

Fath, T., Ke, Y. D., Gunning, P., Götz, J. & Ittner, L. M., 16 Mar 2009, In : Nature Protocols. 4, 1, p. 78-85 8 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)
2008

A new neurotrophic support culture technique for primary neurons

Ke, Y. D., Ittner, L. M., Gunning, P., Gotz, J. & Fath, T., 1 Jul 2008, In : Alzheimer's and Dementia. 4, 4 Supplement, p. T248 1 p., P1-142.

Research output: Contribution to journalMeeting abstract

Divergent regulation of the sarcomere and the cytoskeleton

Schevzov, G., Fath, T., Vrhovski, B., Vlahovich, N., Rajan, S., Hook, J., Joya, J. E., Lemckert, F., Puttur, F., Lin, J. J-C., Hardeman, E. C., Wieczorek, D. F., O'Neill, G. M. & Gunning, P. W., 4 Jan 2008, In : Journal of Biological Chemistry. 283, 1, p. 275-283 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response

Götz, J., David, D., Hoerndli, F., Ke, Y. D., Schonrock, N., Wiesner, A., Fath, T., Bokhari, L., Lim, Y-A., Deters, N. & Ittner, L. M., 1 Mar 2008, In : Neurodegenerative Diseases. 5, 3-4, p. 179-181 3 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Ittner, L. M., Fath, T., Ke, Y. D., Bi, M., Van Eersel, J., Li, K. M., Gunning, P. & Götz, J., 14 Oct 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 41, p. 15997-16002 6 p.

Research output: Contribution to journalArticle

150 Citations (Scopus)

Parkinsonism and memory impairment in tau transgenic mice with axonal transport defects

Ittner, L. M., Ke, Y. D., Fath, T., Schonrock, N., Gunning, P. & Gotz, J., 1 Jul 2008, In : Alzheimer's and Dementia. 4, 4 Supplement, p. T408 1 p., P2-129.

Research output: Contribution to journalArticle

2007

Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice

Hundelt, M., Selle, K., Kosfeld, A., Fath, T., Schultz, C., Götz, J., von Engelhardt, J., Monyer, H. & Brandt, R., 2007, In : BMC Neuroscience. 8, Suppl 1, p. P27 1 p.

Research output: Contribution to journalArticle

2004

Tropomodulin and actin pointed-end dynamics in neuronal model systems

Fath, T. & Fowler, V. M., 1 Nov 2004, In : Molecular Biology of the Cell. 15, Supplement, p. 25A 1 p.

Research output: Contribution to journalMeeting abstract

2002

Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease

Fath, T., Eidenmüller, J. & Brandt, R., 15 Nov 2002, In : Journal of Neuroscience. 22, 22, p. 9733-9741 9 p.

Research output: Contribution to journalArticle

180 Citations (Scopus)
2001

Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein

Eidenmüller, J., Fath, T., Maas, T., Pool, M., Sontag, E. & Brandt, R., 1 Aug 2001, In : Biochemical Journal. 357, 3, p. 759-767 9 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)
2000

Herpes simplex virus-mediated expression of the axonal protein tau in human model neurons (NT2-N cells)

Fath, T., Eidenmüller, J., Maas, T. & Brandt, R., 15 Jan 2000, In : Microscopy Research and Technique. 48, 2, p. 85-96 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins

Eidenmuller, J., Fath, T., Hellwig, A., Reed, J., Sontag, E. & Brandt, R., 8 Nov 2000, In : Biochemistry. 39, 43, p. 13166-13175 10 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)