• 91 Citations
  • 3 h-Index
20152019
If you made any changes in Pure these will be visible here soon.

Research Outputs 2015 2019

  • 91 Citations
  • 3 h-Index
  • 6 Article
  • 2 Review article
2019

Kynurenine pathway metabolites as biomarkers for Amyotrophic Lateral Sclerosis

Tan, V. X. & Guillemin, G. J., 20 Sep 2019, In : Frontiers in Neuroscience. 13, p. 1-11 11 p., 1013.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Kynurenine
Amyotrophic Lateral Sclerosis
Biomarkers
Body Fluids
Blood-Brain Barrier

Neuroprotective effect of myxobacterial extracts on quinolinic acid-induced toxicity in primary human neurons

Dehhaghi, M., Tan, V., Heng, B., Braidy, N., Mohammadipanah, F. & Guillemin, G. J., Feb 2019, In : Neurotoxicity Research. 35, 2, p. 281-290 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Quinolinic Acid
Neuroprotective Agents
Neurons
Toxicity
Stigmatella

Protective effects of myxobacterial extracts on hydrogen peroxide-induced toxicity on human primary astrocytes

Dehhaghi, M., Tan, V., Heng, B., Mohammadipanah, F. & Guillemin, G. J., 10 Feb 2019, In : Neuroscience. 399, p. 1-11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Hydrogen Peroxide
Oxidative Stress
Cell Death
Myxococcales
2018

Detection of the cyanotoxins L-BMAA uptake and accumulation in primary neurons and astrocytes

Tan, V. X., Mazzocco, C., Varney, B., Bodet, D., Guillemin, T. A., Bessede, A. & Guillemin, G. J., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 55–61 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Neurons
Toxicity
Brain
Neurodegenerative diseases

Neurotoxicity of the cyanotoxin BMAA through axonal degeneration and intercellular spreading

Tan, V. X., Lassus, B., Lim, C. K., Tixador, P., Courte, J., Bessede, A., Guillemin, G. J. & Peyrin, J. M., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 62-75 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Neurons
Corpus Striatum
Toxicity
Neurodegenerative diseases
Microfluidics
2017

Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis

Lee, J. M., Tan, V., Lovejoy, D., Braidy, N., Rowe, D. B., Brew, B. J. & Guillemin, G. J., Jan 2017, In : Neuropharmacology. 112, p. 346-364 19 p.

Research output: Contribution to journalReview articleResearchpeer-review

Quinolinic Acid
Amyotrophic Lateral Sclerosis
Kynurenine
Biochemical Phenomena
Motor Neuron Disease

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

Lim, C. K., Bilgin, A., Lovejoy, D. B., Tan, V., Bustamante, S., Taylor, B. V., Bessede, A., Brew, B. J. & Guillemin, G. J., 3 Feb 2017, In : Scientific Reports. 7, p. 1-9 9 p., 41473.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Kynurenine
Metabolomics
Multiple Sclerosis
Kynurenic Acid
Quinolinic Acid
2015

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis

Sundaramoorthy, V., Walker, A. K., Tan, V., Fifita, J. A., McCann, E. P., Williams, K. L., Blair, I. P., Guillemin, G. J., Farg, M. A. & Atkin, J. D., 1 Jul 2015, In : Human molecular genetics. 24, 13, p. 3830-3846 17 p., ddv126.

Research output: Contribution to journalArticleResearchpeer-review

Amyotrophic Lateral Sclerosis
Motor Neurons
Lysosomes
Autophagy
Mutation