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Research Outputs 2009 2018

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2018

Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation

Deng, W., Chen, W., Clement, S., Guller, A., Zhao, Z., Engel, A. & Goldys, E. M., 13 Jul 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 2713.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Liposomes
genes
delivery
drugs
platforms

Photoresponsive endosomal escape enhances gene delivery using liposome-polycation-DNA (LPD) nanovectors

Chen, W., Deng, W., Xu, X., Zhao, X., Vo, J. N., Anwer, A. G., Williams, T. C., Cui, H. & Goldys, E. M., 28 Aug 2018, In : Journal of Materials Chemistry B. 6, 32, p. 5269-5281 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Liposomes
DNA
Genes
Plasmids
Lipids

X-ray radiation-induced and targeted photodynamic therapy with folic acid-conjugated biodegradable nanoconstructs

Clement, S., Chen, W., Deng, W. & Goldys, E. M., 19 Jun 2018, In : International Journal of Nanomedicine. 13, p. 3553-3570 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Photodynamic therapy
Photochemotherapy
Folic Acid
X-Rays
Radiation
2017

Light-triggerable liposomes for enhanced endolysosomal escape and gene silencing in PC12 cells

Chen, W., Deng, W. & Goldys, E. M., 16 Jun 2017, In : Molecular Therapy - Nucleic Acids. 7, p. 366-377 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
PC12 Cells
Gene Silencing
Liposomes
Gene Knockdown Techniques
Light
Open Access
File
Singlet Oxygen
Photosensitizing Agents
Photosensitizers
Liposomes
Cytotoxicity

Nanoparticle-mediated singlet oxygen generation from photosensitizers

Clement, S., Sobhan, M., Deng, W., Camilleri, E. & Goldys, E. M., 1 Jan 2017, In : Journal of Photochemistry and Photobiology A: Chemistry. 332, p. 66-71 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Singlet Oxygen
Photosensitizing Agents
Photosensitizers
Nanoparticles
nanoparticles
2016

PLGA nanocomposites loaded with verteporfin and gold nanoparticles for enhanced photodynamic therapy of cancer cells

Deng, W., Kautzka, Z., Chen, W. & Goldys, E. M., 2016, In : RSC Advances. 6, 113, p. 112393-112402 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Photodynamic therapy
Gold
Nanocomposites
Cells
Nanoparticles

X-ray induced singlet oxygen generation by nanoparticle-photosensitizer conjugates for photodynamic therapy: determination of singlet oxygen quantum yield

Clement, S., Deng, W., Camilleri, E., Wilson, B. C. & Goldys, E. M., 28 Jan 2016, In : Scientific Reports. 6, p. 1-9 9 p., 19954.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Singlet Oxygen
Photosensitizing Agents
Photochemotherapy
Nanoparticles
X-Rays
2015

Bright, water-soluble CeF3 photo-, cathodo-, and X-ray luminescent nanoparticles

Clement, S., Deng, W., Drozdowicz-Tomsia, K., Liu, D., Zachreson, C. & Goldys, E. M., 2015, In : Journal of Nanoparticle Research. 17, 1, p. 1-9 9 p., 7.

Research output: Contribution to journalArticleResearchpeer-review

Nanoparticles
Photoluminescence
Water
X rays
nanoparticles

Gene interference with morpholinos in a gold nanoparticle-based delivery platform in rat PC12 cells

Deng, W., Farnham, M. M. J., Goldys, E. M., Mohammed, S. & Pilowsky, P. M., 1 Dec 2015, In : Journal of Biomedical Nanotechnology. 11, 12, p. 2111-2123 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Morpholinos
Pituitary Adenylate Cyclase-Activating Polypeptide
PC12 Cells
Gene Knockdown Techniques
Gold

Medically relevant assays with a simple smartphone and tablet based fluorescence detection system

Wargocki, P., Deng, W., Anwer, A. G. & Goldys, E. M., 20 May 2015, In : Sensors (Switzerland). 15, 5, p. 11653-11664 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
tablets
Smartphones
Tablets
trypsin
Assays
2014

Optogenetics, the intersection between physics and neuroscience: light stimulation of neurons in physiological conditions

Deng, W., Goldys, E. M., Farnham, M. M. J. & Pilowsky, P. M., 1 Dec 2014, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 307, 11, p. R1292-R1302 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Optogenetics
Physics
Neurosciences
Neurons
Light

Practical implementation, characterization and applications of a multi-colour time-gated luminescence microscope

Zhang, L., Zheng, X., Deng, W., Lu, Y., Lechevallier, S., Ye, Z., Goldys, E. M., Dawes, J. M., Piper, J. A., Yuan, J., Verelst, M. & Jin, D., 13 Oct 2014, In : Scientific Reports. 4, p. 1-6 6 p., 6597.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Luminescence
Color
Europium
Terbium
Cryptosporidium parvum
2012

Plasmonic approach to enhanced fluorescence for applications in biotechnology and the life sciences

Deng, W. & Goldys, E. M., 10 Jul 2012, In : Langmuir. 28, 27, p. 10152-10163 12 p.

Research output: Contribution to journalArticleResearchpeer-review

biotechnology
life sciences
Biotechnology
Fluorophores
Fluorescence
2011

Automated detection of rare-event pathogens through time-gated luminescence scanning microscopy

Lu, Y., Jin, D., Leif, R. C., Deng, W., Piper, J. A., Yuan, J., Duan, Y. & Huo, Y., May 2011, In : Cytometry Part A. 79A, 5, p. 349-355 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Giardia
Luminescence
Microscopy
Cysts
Europium

Barstar:barnase - a versatile platform for colloidal diamond bioconjugation

Sreenivasan, V. K. A., Ivukina, E. A., Deng, W., Kelf, T. A., Zdobnova, T. A., Lukash, S. V., Veryugin, B. V., Stremovskiy, O. A., Zvyagin, A. V. & Deyev, S. M., 7 Jan 2011, In : Journal of Materials Chemistry. 21, 1, p. 65-68 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanodiamonds
Diamond
Diamonds
Proteins
Bacillus amyloliquefaciens ribonuclease

Ultrabright Eu-Doped Plasmonic Ag@SiO2 Nanostructures: Time-gated Bioprobes with Single Particle Sensitivity and Negligible Background

Deng, W., Jin, D., Drozdowicz-Tomsia, K., Yuan, J., Wu, J. & Goldys, E. M., 25 Oct 2011, In : Advanced Materials. 23, 40, p. 4649-4654 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Bioassay
Silver
Silicon Dioxide
Nanostructures
Nanocomposites

Upconversion in NaYF4:Yb, Er nanoparticles amplified by metal nanostructures

Deng, W., Sudheendra, L., Zhao, J., Fu, J., Jin, D., Kennedy, I. M. & Goldys, E. M., 19 Jul 2011, In : Nanotechnology. 22, 32, p. 1-8 8 p., 325604.

Research output: Contribution to journalArticleResearchpeer-review

Nanostructures
Metals
Nanoshells
Nanoparticles
Luminescence
2010

Europium chelate (BHHCT-Eu3+) and its metal nanostructure enhanced luminescence applied to bioassays and time-gated bioimaging

Deng, W., Jin, D., Drozdowicz-Tomsia, K., Yuan, J. & Goldys, E. M., 15 Jun 2010, In : Langmuir. 26, 12, p. 10036-10043 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Europium
bioassay
Nanostructures
Bioassay
europium
2009

Enhanced flow cytometry-based bead immunoassays using metal nanostructures

Deng, W., Drozdowicz-Tomsia, K., Jin, D. & Goldys, E. M., 1 Sep 2009, In : Analytical Chemistry. 81, 17, p. 7248-7255 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Flow cytometry
Nanostructures
Metals
Fluorescence
Silicon Dioxide