Projects per year
Personal profile
Biography
Yuanyuan completed a PhD in Biomedical Science in 2022. Currently a Postdoctoral Fellow at Macquarie University in the Dementia Research Centre, focusing on the pathogenesis of Alzheimer's disease and related gene-target therapy. Previously working as a researcher and lecturer at the Key Laboratory of Basic Pharmacology of the Ministry of Education, China, focused on the effects and mechanisms of herbal medicine in neurodegenerative disease treatment. Interests in neurosciences, herbal medicine, brain aging, and cognitive disorders.
Education/Academic qualification
Neuroscience, Doctor of Philosophy, The role of cell cycle and excitotoxicity in Alzheimer’s disease pathogenesis, Macquarie University
Dec 2018 → Oct 2022
Award Date: 27 Oct 2022
Pharmacology , Research Master of Pharmacology , Study on Strategies of Promoting Immunotherapy with Tumor Interstitial Cells as Target, Jinan University
11 Sept 2010 → 25 Jun 2013
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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2022 NHMRC Ideas: Inhibition failure in Alzheimer's disease
Ittner, L., van der Hoven, J., Deng, Y., Forrest, S., Ke, Y. & Kovacs, G.
1/01/23 → 31/12/26
Project: Research
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Research Outputs
- 22 Article
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Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice
Ke, Y. D., van Hummel, A., Au, C., Chan, G., Lee, W. S., van der Hoven, J., Przybyla, M., Deng, Y., Sabale, M., Morey, N., Bertz, J., Feiten, A., Ippati, S., Stevens, C. H., Yang, S., Gladbach, A., Haass, N. K., Kril, J. J., Blair, I. P., Delerue, F., & 1 others, 17 Apr 2024, In: Neuron. 112, 8, p. 1249-1264.e8 25 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease
Deng, Y., Bi, M., Delerue, F., Forrest, S. L., Chan, G., van der Hoven, J., van Hummel, A., Feiten, A. F., Lee, S., Martinez-Valbuena, I., Karl, T., Kovacs, G. G., Morahan, G., Ke, Y. D. & Ittner, L. M., Oct 2022, In: Acta Neuropathologica. 144, 4, p. 637-650 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)62 Downloads (Pure) -
Isorhynchophylline ameliorates cerebral ischemia/reperfusion injury by inhibiting CX3CR1-mediated microglial activation and neuroinflammation
Deng, Y., Tan, R., Li, F., Liu, Y., Shi, J. & Gong, Q., 12 Feb 2021, In: Frontiers in Pharmacology. 12, p. 1-9 9 p., 574793.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)48 Downloads (Pure) -
Rapid initiation of cell cycle reentry processes protects neurons from amyloid-β toxicity
Ippati, S., Deng, Y., Hoven, J. V. D., Heu, C., Hummel, A. V., Chua, S. W., Paric, E., Chan, G., Feiten, A., Fath, T., Ke, Y. D., Haass, N. K. & Ittner, L. M., 23 Mar 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 12, p. 1-9 9 p., e2011876118.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Syntaxins 6 and 8 facilitate tau into secretory pathways
Lee, W. S., Tan, D. C. S., Deng, Y., van Hummel, A., Ippati, S., Stevens, C., Carmona-Mora, P., Ariawan, D., Hou, L., Stefen, H., Tomanic, T., Bi, M., Tomasetig, F., Martin, A., Fath, T., Palmer, S., Ke, Y. D. & Ittner, L. M., 16 Apr 2021, In: Biochemical Journal. 478, 7, p. 1471–1484 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)53 Downloads (Pure)