Projects per year
Personal profile
Biography
Yuanyuan completed a PhD in Biomedical Science in 2022. Currently a Postdoctoral Fellow at Macquarie University in the Dementia Research Centre, focusing on the pathogenesis of Alzheimer's disease and related gene-target therapy. Previously working as a researcher and lecturer at the Key Laboratory of Basic Pharmacology of the Ministry of Education, China, focused on the effects and mechanisms of herbal medicine in neurodegenerative disease treatment. Interests in neurosciences, herbal medicine, brain aging, and cognitive disorders.
Education/Academic qualification
Neuroscience, Doctor of Philosophy, The role of cell cycle and excitotoxicity in Alzheimer’s disease pathogenesis, Macquarie University
Dec 2018 → Oct 2022
Award Date: 27 Oct 2022
Pharmacology , Research Master of Pharmacology , Study on Strategies of Promoting Immunotherapy with Tumor Interstitial Cells as Target, Jinan University
11 Sept 2010 → 25 Jun 2013
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting tau for the treatment of SYNGAP-1 Encephalopathy
Ittner, L. (Primary Chief Investigator), Van Eersel, J. (Chief Investigator) & Deng, Y. (Associate Investigator)
1/08/25 → 1/02/27
Project: Research
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FightMND 24: Inhibition failure in Motor Neuron Disease
Ittner, L. (Primary Chief Investigator), Ke, Y. (Co-Investigator) & Deng, Y. (Co-Investigator)
1/03/25 → 29/02/28
Project: Research
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2022 NHMRC Ideas: Inhibition failure in Alzheimer's disease
Ittner, L. (Primary Chief Investigator), van der Hoven, J. (Chief Investigator), Deng, Y. (Chief Investigator), Forrest, S. (Chief Investigator), Ke, Y. (Associate Investigator) & Kovacs, G. (Associate Investigator)
1/01/23 → 31/12/26
Project: Research
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Macquarie Medical School Small Grant Scheme Award 2021
Deng, Y. (Primary Chief Investigator)
1/07/21 → 6/12/21
Project: Research
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Engineered cyclotide blocks neuronal excitotoxicity
Ariawan, D., van der Hoven, J., Morey, N., Pushpitha, K., Genoud, S., Stefen, H., Veltman, S., Przybyla, M., Deng, Y., Fath, T., Tietz, O., van Eersel, J. & Ittner, L. M., 13 Mar 2025, In: Journal of Medicinal Chemistry. 68, 5, p. 5211-5221 11 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus) -
PLP1-targeting antisense oligonucleotides improve FOXG1 syndrome mice
Tan, D. C. S., Jung, S., Deng, Y., Morey, N., Chan, G., Bongers, A., Ke, Y. D., Ittner, L. M. & Delerue, F., 9 Oct 2024, In: International Journal of Molecular Sciences. 25, 19, p. 1-21 21 p., 10846.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)97 Downloads (Pure) -
Septin6 as a new approach for AD treatment
Liu, S., Pei, H., Deng, Y. & Xie, W., 2024, In: Acta Materia Medica. 3, 3, p. 309-311 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)63 Downloads (Pure) -
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice
Ke, Y. D., van Hummel, A., Au, C., Chan, G., Lee, W. S., van der Hoven, J., Przybyla, M., Deng, Y., Sabale, M., Morey, N., Bertz, J., Feiten, A., Ippati, S., Stevens, C. H., Yang, S., Gladbach, A., Haass, N. K., Kril, J. J., Blair, I. P. & Delerue, F. & 1 others, , 17 Apr 2024, In: Neuron. 112, 8, p. 1249-1264.e8 25 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Link opens in a new tab Citations (Scopus) -
Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease
Deng, Y., Bi, M., Delerue, F., Forrest, S. L., Chan, G., van der Hoven, J., van Hummel, A., Feiten, A. F., Lee, S., Martinez-Valbuena, I., Karl, T., Kovacs, G. G., Morahan, G., Ke, Y. D. & Ittner, L. M., Oct 2022, In: Acta Neuropathologica. 144, 4, p. 637-650 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Link opens in a new tab Citations (Scopus)73 Downloads (Pure)