Calpeptin, and related candidates, for the treatment of Machado Joseph disease

Laird, Angela (Primary Chief Investigator)
Nicholson, Garth (Chief Investigator)
Walker, Adam Keith (Chief Investigator)
Cole, Nicholas (Chief Investigator)
Lee, Albert (Chief Investigator)
Morsch, Marco (Chief Investigator)
Davis, Rohan (Chief Investigator)
Guillemin, Gilles (Associate Investigator)
Atkin, Julie (Associate Investigator)
Ooi, Lezanne (Associate Investigator)

Deputy Vice-Chancellor (Research) - Office

Project: Research

Status	Finished
Effective start/end date	1/01/18 → 31/12/21

4 Article
1 Review article

A novel calpain inhibitor compound has protective effects on a zebrafish model of spinocerebellar ataxia type 3
Robinson, K. J., Yuan, K., Plenderleith, S. K., Watchon, M. & Laird, A., 29 Sep 2021, In: Cells. 10, 10, p. 1-15 15 p., 2592.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Citations (Scopus)

21 Downloads (Pure)
Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3
Robinson, K. J., Tym, M. C., Hogan, A., Watchon, M., Yuan, K. C., Plenderleith, S. K., Don, E. K. & Laird, A. S., 1 Oct 2021, In: DMM Disease Models and Mechanisms. 14, 10, p. 1-12 12 p., dmm049023.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

19 Downloads (Pure)
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo
Watchon, M., Luu, L., Robinson, K. J., Yuan, K. C., De Luca, A., Suddull, H. J., Tym, M. C., Guillemin, G. J., Cole, N. J., Nicholson, G. A., Chung, R. S., Lee, A. & Laird, A. S., 20 Aug 2021, In: Molecular Brain. 14, 1, p. 1-16 16 p., 128.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

5 Downloads (Pure)