Clinical development of radioimmunotherauputic anti-Glypican 1 antibodies for the diagnosis and treatment of solid and metastatic cancers

  • Lengkeek, Nigel (Chief Investigator)
  • Jamie, Joanne (Primary Chief Investigator)
  • King, Andrew (PhD Student)

Project: Research

Project Details

Description

In this project the student will, 1) Develop and optimise the smallscale
production of chelator (DOTA) functionalised Miltuximab using stochastic or
site-specific labelling techniques to reproducibly create functionalised antibodies
with up to three target chelator-to-antibody ratios; 2) Develop and deploy the analytical techniques required to characterise the functionalised antibodies; 3)
Undertake the radiolabelling and radiochemical characterisation of at least one of
the functionalised antibodies and 4) contribute to the in vitro and in vivo
assessment of the functionalised antibodies.
Short titleANSTO Top-Up Scholarship
StatusFinished
Effective start/end date1/01/2131/12/22