Development of a laser-based testing platform for dry powder inhaler (DPI) evaluation and in-silico model validation

This proposal aims to provide generic inhaled drug companies with enhanced means to undertake drug formulation/device development-related work easily. This is achieved by characterizing aerosol delivery and deposition behavior in inhaler devices and realistic human airway replicas that represent the wide population and across ages. Scientific measurements of aerosol flow and deposition are produced using multimodality tools that encompass laser diagnostics and optical coherence tomography. A bid to the FDA is required before giving the green light to submit the proposal, and approval was granted last week.