Disruption to intracellular trafficking as a central pathogenic mechanism in amyotrophic lateral sclerosis

Atkin, Julie (Primary Chief Investigator)
Cole, Nicholas (Chief Investigator)
Chung, Roger (Chief Investigator)
Rizos, Helen (Associate Investigator)
Bell, Toby (Associate Investigator)

Project: Research

Status	Active
Effective start/end date	1/01/15 → …

8 Article
5 Review article

Protein disulfide isomerase endoplasmic reticulum protein 57 (ERp57) is protective against ALS-associated mutant TDP-43 in neuronal cells
Parakh, S., Perri, E. R., Vidal, M., Takalloo, Z., Jagaraj, C. J., Mehta, P., Yang, S., Thomas, C. J., Blair, I. P., Hong, Y. & Atkin, J. D., Dec 2024, In: NeuroMolecular Medicine. 26, 1, p. 1-15 15 p., 23.
Research output: Contribution to journal › Article › peer-review

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ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation
Ragagnin, A. M. G., Sundaramoorthy, V., Farzana, F., Gautam, S., Saravanabavan, S., Takalloo, Z., Mehta, P., Do-Ha, D., Parakh, S., Shadfar, S., Hunter, J., Vidal, M., Jagaraj, C. J., Brocardo, M., Konopka, A., Yang, S., Rayner, S. L., Williams, K. L., Blair, I. P., Chung, R. S., & 3 othersLee, A., Ooi, L. & Atkin, J. D., 22 Nov 2023, In: Scientific Reports. 13, 1, p. 1-20 20 p., 20467.
Research output: Contribution to journal › Article › peer-review

Open Access
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1 Citation (Scopus)

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DNA damage, defective DNA repair, and neurodegeneration in amyotrophic lateral sclerosis
Konopka, A. & Atkin, J. D., 27 Apr 2022, In: Frontiers in Aging Neuroscience. 14, p. 1-15 15 p., 786420.
Research output: Contribution to journal › Review article › peer-review

Open Access
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17 Citations (Scopus)

60 Downloads (Pure)