Disruption to intracellular trafficking as a central pathogenic mechanism in amyotrophic lateral sclerosis

Project: Research

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Effective start/end date	1/01/15 → …

The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish models
Parakh, S., Shadfar, S., Perri, E. R., Ragagnin, A. M. G., Piattoni, C. V., Fogolín, M. B., Yuan, K. C., Shahheydari, H., Don, E. K., Thomas, C. J., Hong, Y., Comini, M. A., Laird, A. S., Spencer, D. M. & Atkin, J. D., 22 May 2020, In : iScience. 23, 5, p. 1-27 44 p., 101097.
Research output: Contribution to journal › Article

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Protein disulphide isomerase is associated with mutant SOD1 in canine degenerative myelopathy
Chang, R. C., Parakh, S., Coates, J. R., Long, S. & Atkin, J. D., 2 Jan 2019, In : NeuroReport. 30, 1, p. 8-13 6 p.
Research output: Contribution to journal › Article
3 Citations (Scopus)
A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro
Fifita, J. A., Williams, K. L., Sundaramoorthy, V., Mccann, E. P., Nicholson, G. A., Atkin, J. D. & Blair, I. P., 2 Jan 2017, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 18, 1-2, p. 126-133 8 p.
Research output: Contribution to journal › Article
14 Citations (Scopus)