From Bundle to Synapse: Using Novel Tools to Understand Mammalian Balance Function for Translational Outcomes.

This application seeks to solve the underlying physiology of the mammalian balance system, using an array of novel, state-of-the-art techniques. A detailed understanding of the mammalian balance system is limited due to our lack of objective tools to study its function. This greatly limits technological and translational innovation. The project will generate fundamental knowledge regarding the activation of balance receptors over a wide range of sensory inputs, from gravity to light. Expected outcomes include a "bottom-up", holistic understanding of mammalian balance function which will drive a prolific phase of translational research, enhancing cross-disciplinary capabilities at Macquarie, across Australia and overseas.