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How does TDP-43 stay soluble and functional – Identifying molecular targets for early TDP-43 condensation

  • Morsch, Marco (Primary Chief Investigator)
  • Alberti, Simon (Co-Investigator)
  • McAlary, Luke (Chief Investigator)
  • Maurel, Cindy (Chief Investigator)
  • Walker, Adam Keith (Associate Investigator)
  • Lisowski, Leszek (Associate Investigator)
  • Ecroyd, Heath (Associate Investigator)

Project: Research

Project Details

Description

Discovery
The overarching hypothesis of this proposal is whether the molecular mechanisms that maintain TDP-43 liquid-like - and therefore functional - can be harvested to combat neurodegeneration in ALS.
AcronymFightMND 24
StatusActive
Effective start/end date3/03/25 → 2/03/28