Investigating cyanobacteria toxin as a causative environmental factor in pathogenesis of ALS

Increasing global temperatures have led to an increase in blue green algae blooms, while the toxic effects of its toxin BMAA in causing MND is still unclear. We investigate how BMAA kills neurons and how it may spread from one cell to another. This will allow us to understand the mechanisms in BMAA that cause loss of function, and lead to the development of target therapy that can retain function, and stop the spread of BMAA.