Modulating actin dynamics in ALS/MND as a novel therapeutic approach

  • Atkin, Julie (Primary Chief Investigator)
  • Woodruff, Trent M. (Chief Investigator)
  • Karl, Tim (Chief Investigator)
  • Craik, David (Chief Investigator)
  • Guillemin, Gilles (Chief Investigator)
  • Laird, Angela (Chief Investigator)

    Project: Research

    Project Details

    Description

    Actin is the most abundant protein in humans, with many important functions requiring its continuous assembly and disassembly into long polymers. We have obtained exciting new evidence this process is disrupted in MND. Here, drugs that restore dynamic actin assembly will be examined as a new treatment for MND.
    StatusActive
    Effective start/end date4/01/21 → 3/01/24