Project Details
Description
We are now able to modify genomes thoroughly to generate industrial
microorganisms with new and improved biological functions. However, current
methods require the laborious construction of entire synthetic genomes, which is highly time- and resource-demanding while also restricted to species that allow the in vivo assembly of DNA. This project aims to overcome these limitations by enabling rapid and cost-effective radical genome modifications in virtually any species. Expected outcomes include a powerful tool for studying genome function and expediting the development of improved organisms for biotechnological applications. This project would also open the door to the exciting possibility of engineering multispecies hybrid genomes.
microorganisms with new and improved biological functions. However, current
methods require the laborious construction of entire synthetic genomes, which is highly time- and resource-demanding while also restricted to species that allow the in vivo assembly of DNA. This project aims to overcome these limitations by enabling rapid and cost-effective radical genome modifications in virtually any species. Expected outcomes include a powerful tool for studying genome function and expediting the development of improved organisms for biotechnological applications. This project would also open the door to the exciting possibility of engineering multispecies hybrid genomes.
| Status | Finished |
|---|---|
| Effective start/end date | 1/01/19 → 31/12/20 |