Particle based nasal drug delivery for the treatment of chronic fatigue syndrome

The clinical treatments currently available for chronic fatigue syndrome (CFS) are limited. Despite a strong correlation of CFS to high levels of neuroinflammation, no technologies have been approved for long term CFS treatment that can deliver a sustained and appropriate dose of anti-inflammatory drugs to the brain. This project will develop nanotechnology based tools for nasal delivery of anti-inflammatory drugs. This innovation can decrease the debilitating symptoms of CFS linked to neuroinflammation and minimise the adverse side effects experienced using oral drug treatments. The project outcomes will help to understand the potential applications of nanotechnologies in the treatment of neuroinflammation.