Single Cell Proteomics Platform

This proposal will establish a state-of-the-art platform to characterise protein function at the single-cell level across a range of biological samples including yeast, plants, animals and humans. It will provide new insights into the differentiation of cellular functions across many different cell types in multicellular organisms, which cannot be achieved by bulk analysis of whole tissues. Expected outcomes include identification of new biological pathways and associated complex and high-value protein molecules. Such new fundamental knowledge of biological processes will enable future efforts in the National Reconstruction Fund Priority for medical science and agriculture and boost Australia’s competitiveness in these global industries.