Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ shows minor groove AT selectivity with oligonucleotides

Emma M. Proudfoot; Joel P. Mackay; Robert S. Vagg; Kymberley A. Vickery; Peter A. Williams; Peter Karuso

Δ-cis-α-[Ru(RR-picchxnMe₂)(phen)]²⁺ shows minor groove AT selectivity with oligonucleotides

Emma M. Proudfoot, Joel P. Mackay, Robert S. Vagg, Kymberley A. Vickery, Peter A. Williams, Peter Karuso

Department of Molecular Sciences

Research output: Contribution to journal › Article

19 Citations (Scopus)

Abstract

NMR studies show that the ternary octahedral Δ-cis-α-[Ru(RR-picchxnMe₂)(phen)]²⁺ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)₂] and [d(ATATCGATAT)₂] duplexes through a non-intercalative interaction.

Original language	English
Pages (from-to)	1623-1624
Number of pages	2
Journal	Chemical Communications
Issue number	17
Publication status	Published - 1997

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title = "Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ shows minor groove AT selectivity with oligonucleotides",

abstract = "NMR studies show that the ternary octahedral Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)2] and [d(ATATCGATAT)2] duplexes through a non-intercalative interaction.",

author = "Proudfoot, {Emma M.} and Mackay, {Joel P.} and Vagg, {Robert S.} and Vickery, {Kymberley A.} and Williams, {Peter A.} and Peter Karuso",

year = "1997",

language = "English",

pages = "1623--1624",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "17",

}

TY - JOUR

T1 - Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ shows minor groove AT selectivity with oligonucleotides

AU - Proudfoot, Emma M.

AU - Mackay, Joel P.

AU - Vagg, Robert S.

AU - Vickery, Kymberley A.

AU - Williams, Peter A.

AU - Karuso, Peter

PY - 1997

Y1 - 1997

N2 - NMR studies show that the ternary octahedral Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)2] and [d(ATATCGATAT)2] duplexes through a non-intercalative interaction.

AB - NMR studies show that the ternary octahedral Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)2] and [d(ATATCGATAT)2] duplexes through a non-intercalative interaction.

UR - http://www.scopus.com/inward/record.url?scp=0002537121&partnerID=8YFLogxK

M3 - Article

SP - 1623

EP - 1624

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 17

ER -