Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ shows minor groove AT selectivity with oligonucleotides

Emma M. Proudfoot, Joel P. Mackay, Robert S. Vagg, Kymberley A. Vickery, Peter A. Williams, Peter Karuso

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

NMR studies show that the ternary octahedral Δ-cis-α-[Ru(RR-picchxnMe2)(phen)]2+ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)2] and [d(ATATCGATAT)2] duplexes through a non-intercalative interaction.

Original languageEnglish
Pages (from-to)1623-1624
Number of pages2
JournalChemical Communications
Issue number17
Publication statusPublished - 1997

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