超临界流体技术制备环糊精包合物的研究进展

Translated title of the contribution: Progress in preparation of cyclodextrin complexes using supercritical fluid process

Wei Zhang, Zhiyun Zhang, Qiuyuan Li, Tong Li, Lihong Wang, Lili Zhou

Research output: Contribution to journalArticle

Abstract

Supercritical fluid possesses the advantages of both the gas and the liquid, such as great solubility, favorable mass transfer capacity, low surface tension and satisfactory permeability. The cyclodextrin complexes prepared by supercritical fluid process have the characteristics of uniform particle size, high purity and no residual solvent. The applications of traditional methods are limited due to the disadvantages, including the requirement of organic or toxic solvents, long drying step and low efficiency. Preparation
of cyclodextrin complexes using supercritical fluid process is still in the initial stage in China. In order to provide a reference for the researchers, in the present paper, the production processes of cyclodextrin complexes by supercritical fluid process are classified, the latest research progress of various processes is summarized and the existing problems are put forward based on a great deal of literature in home and abroad.
Translated title of the contributionProgress in preparation of cyclodextrin complexes using supercritical fluid process
Original languageChinese (Simplified)
Pages (from-to)86-97
Number of pages12
JournalChinese Archives of Traditional Chinese Medicine
Volume5
Issue number8
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • Supercritical fluid process
  • Cyclodextrin
  • Inclusion complexes
  • Preparation

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