Multiplex suspension assay/array using lifetime coding

Dayong Jin (Inventor), Yiqing Lu (Inventor), Jiangbo Zhao (Inventor)

Research output: Patent

Abstract

A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilized for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct color bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.
Original languageEnglish
Patent number09816926
IPCG01N 21/64,C40B 70/00,C09K 11/02,C09K 11/06,C09D 11/50,C09K 11/77
Priority date22/06/12
Publication statusPublished - 14 Nov 2017

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