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Author

  • Gilles Guillemin
2018

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease

Ahmad Rather, M., Justin Thenmozhi, A., Manivasagam, T., Dhivya Bharathi, M., Mohamed Essa, M. & Guillemin, G. J., 1 Jan 2018, In : Frontiers in bioscience (Scholar edition). 10, p. 262-275 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

BMAA and Neurodegenerative Illness

Cox, P. A., Kostrzewa, R. M. & Guillemin, G. J., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 178–183 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes

de Paula Martins, R., Ghisoni, K., Lim, C. K., Aguiar, A. S., Guillemin, G. J. & Latini, A., 1 Feb 2018, In : Free Radical Biology and Medicine. 115, p. 371-382 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2017

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s)

Guo, F., Hu, M., Huang, D., Zhao, Y., Heng, B., Guillemin, G., Lim, C. K., Hawthorne, W. J. & Yi, S., Oct 2017, In : Xenotransplantation. 24, 5, p. 1-11 11 p., e12326.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma

Corre, S., Tardif, N., Mouchet, N., Leclair, H. M., Boussemart, L., Gautron, A., Bachelot, L., Perrot, A., Soshilov, A., Rogiers, A., Rambow, F., Dumontet, E., Tarte, K., Bessede, A., Guillemin, G. J., Marine, J. C., Denison, M. S., Gilot, D. & Galibert, M. D., 14 Nov 2018, In : Nature Communications. 9, 1, p. 1-13 13 p., 4775.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
2 Downloads (Pure)
2016

Chronic treatment with the IDO1 inhibitor 1-methyl-D-tryptophan minimizes the behavioural and biochemical abnormalities induced by unpredictable chronic mild stress in mice - Comparison with fluoxetine

Laugeray, A., Launay, J. M., Callebert, J., Mutlu, O., Guillemin, G. J., Belzung, C. & Barone, P. R., 9 Nov 2016, In : PLoS ONE. 11, 11, p. 1-17 17 p., e0164337.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
11 Downloads (Pure)
2013

Blueberries and health benefits

Vijayan, R. K., Essa, M. M., Al-Rawahi, A. S., Guillemin, G. J., Selvaraju, S. & Memon, M. A., 2013, Food as medicine. Essa, M. M. & Memon, M. A. (eds.). New York: Nova Science Publishers, p. 17-35 19 p. (Food science and technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?

Steiner, J., Walter, M., Gos, T., Guillemin, G. J., Bernstein, H. G., Sarnyai, Z., Mawrin, C., Brisch, R., Bielau, H., zu Schwabedissen, L. M., Bogerts, B. & Myint, A. M., 10 Aug 2011, In : Journal of Neuroinflammation. 8, p. 1-9 9 p., 94.

Research output: Contribution to journalArticle

Open Access
File
319 Citations (Scopus)
7 Downloads (Pure)
2014

Almonds and brain functionality

Essa, M. M., Subash, S., Parvathy, S., Meera, A., Guillemin, G. J., Memon, M. A. & Manivasagam, T., 2014, Food and Brain Health. Essa, M. M., Memon, M. A. & Akbar, M. (eds.). New York: Nova Science Publishers, p. 75-84 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Induction of TDO2 and IDO2 in liver by high-fat feeding in mice: Discrepancies with human obesity

Poulain-Godefroy, O., Eury, E., Leloire, A., Hennart, B., Guillemin, G. J., Allorge, D. & Froguel, P., 2013, In : International Journal of Tryptophan Research. 6, SUPPL.1, p. 29-37 9 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
2 Downloads (Pure)
2014

Preventing Quinolinic acid-induced toxicity in oligodendrocytes with antagonizing monoclonal antibodies and kynurenine pathway inhibitors

Lim, C. K., Sundaram, G., Brew, B. J. & Guillemin, G. J., Jun 2014, In : Multiple Sclerosis. 20, 7, p. 959-960 2 p.

Research output: Contribution to journalMeeting abstract

2017

NAD deficiency, congenital malformations, and niacin supplementation

Shi, H., Enriquez, A., Rapadas, M., Martin, E. M. M. A., Wang, R., Moreau, J., Lim, C. K., Szot, J. O., Ip, E., Hughes, J. N., Sugimoto, K., Humphreys, D. T., McInerney-Leo, A. M., Leo, P. J., Maghzal, G. J., Halliday, J., Smith, J., Colley, A., Mark, P. R., Collins, F. & 13 others, Sillence, D. O., Winlaw, D. S., Ho, J. W. K., Guillemin, G. J., Brown, M. A., Kikuchi, K., Thomas, P. Q., Stocker, R., Giannoulatou, E., Chapman, G., Duncan, E. L., Sparrow, D. B. & Dunwoodie, S. L., 10 Aug 2017, In : New England Journal of Medicine. 377, 6, p. 544-552 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2011

Lead dysregulates serine/threonine protein phosphatases in human neurons

Rahman, A., Brew, B. J. & Guillemin, G. J., Feb 2011, In : Neurochemical Research. 36, 2, p. 195-204 10 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2019

Low molecular weight sulfated chitosan: neuroprotective effect on rotenone-induced in vitro Parkinson’s disease

Manigandan, V., Nataraj, J., Karthik, R., Manivasagam, T., Saravanan, R., Thenmozhi, A. J., Essa, M. M. & Guillemin, G. J., Apr 2019, In : Neurotoxicity Research. 35, 3, p. 505-515 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

Serum tryptophan metabolites and Ido1 expression as biomarkers of mucosal inflammation in ulcerative colitis

Sofia, A., Ciorba, M. A., Meckel, K., Lim, E., Guillemin, G., Bissonnette, M. & Pekow, J., Apr 2016, In : Gastroenterology. 150, 4 Supplement 1, p. S549 1 p., Su1783.

Research output: Contribution to journalMeeting abstract

2018

Tryptophan metabolism through the kynurenine pathway is associated with endoscopic inflammation in ulcerative colitis

Sofia, M. A., Ciorba, M. A., Meckel, K., Lim, C. K., Guillemin, G. J., Weber, C. R., Bissonnette, M. & Pekow, J. R., Jul 2018, In : Inflammatory Bowel Diseases. 24, 7, p. 1471-1480 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2013

Guava and potential health benefits

Essa, M. M., Vijayan, R. K., Al-Rawahi, A. S., Guillemin, G. J., Selvaraju, S. & Memon, M. A., 2013, Food as medicine. Essa, M. M. & Memon, M. A. (eds.). New York: Nova Science Publishers, p. 271-290 20 p. (Food science and technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

The endogenous tryptophan metabolite and NAD(+) precursor quinolinic acid confers resistance of gliomas to oxidative stress

Sahm, F., Oezen, I., Opitz, C. A., Radlwimmer, B., Von Deimling, A., Ahrendt, T., Adams, S., Bode, H. B., Guillemin, G. J., Wick, W. & Platten, M., 1 Jun 2013, In : Cancer Research. 73, 11, p. 3225-3234 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2015

The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions

Radford, R., Rcom-H'cheo-Gauthier, A., Wong, M. B., Eaton, E. D., Quilty, M., Blizzard, C., Norazit, A., Meedeniya, A., Vickers, J. C., Gai, W. P., Guillemin, G. J., West, A. K., Dickson, T. C., Chung, R. & Pountney, D. L., 1 Mar 2015, In : Molecular and Cellular Neuroscience. 65, p. 68-81 14 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2016

Inflammation, immunology, stress and depression: a role for kynurenine metabolism in physical exercise and skeletal muscle

Zepf, F. D., Stewart, R. M., Guillemin, G. J. & Ruas, J. L., 1 Aug 2016, In : Acta Neuropsychiatrica. 28, 4, p. 244-245 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)
2013

Emblica officinalis (Amla) as medicine

Hakkim, F. L., Essa, M. M., Guillemin, G. J., Al-Rawahi, A. S., Memon, M. A., Vijayan, R. K. & Subash, S., 2013, Food as medicine. Essa, M. M. & Memon, M. A. (eds.). New York: Nova Science Publishers, p. 205-221 17 p. ( Food science and technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Effect of alginate encapsulation on the cellular transcriptome of human islets

Vaithilingam, V., Quayum, N., Joglekar, M. V., Jensen, J., Hardikar, A. A., Oberholzer, J., Guillemin, G. J. & Tuch, B. E., Nov 2011, In : Biomaterials. 32, 33, p. 8416-8425 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2019
12 Citations (Scopus)
2011

Characterization of the kynurenine pathway in NSC-34 cell line: Implications for amyotrophic lateral sclerosis

Chen, Y., Brew, B. J. & Guillemin, G. J., Sep 2011, In : Journal of Neurochemistry. 118, 5, p. 816-825 10 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012

Foreword

Guillemin, G. J., Aug 2012, Natural Products and Their Active Compounds on Disease Prevention. Essa, M. M., Manickavasagan, A. & Sukumar, E. (eds.). New York: Nova Science Publishers, p. ix-x 2 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript/introduction

Walnuts (juglans regia linn) and its health benefits

Essa, M. M., Guillemin, G. J., Al-Rawahi, A. S., Singh, V., Guizani, N. & Memon, A. M., 2012, Natural Products and Their Active Compounds on Disease Prevention. Essa, M. M., Manickavasagan, A. & Sukumar, E. (eds.). New York: Nova Science Publishers, p. 333-349 17 p. (Food Science and Technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria

Bakmiwewa, S. M., Weiser, S., Grey, M., Heng, B., Guillemin, G. J., Ball, H. J. & Hunt, N. H., 1 Feb 2016, In : Cytokine. 78, p. 79-86 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Chronic mild stress augments MPTP induced neurotoxicity in a murine model of Parkinson's disease

Janakiraman, U., Manivasagam, T., Thenmozhi, A. J., Dhanalakshmi, C., Essa, M. M., Song, B. J. & Guillemin, G. J., 1 May 2017, In : Physiology and Behavior. 173, p. 132-143 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016

Kynurenines, gender and neuroinflammation; showcase schizophrenia

de Bie, J., Lim, C. K. & Guillemin, G. J., 1 Oct 2016, In : Neurotoxicity Research. 30, 3, p. 285-294 10 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)
2012

Design and Screening of a Glial Cell-Specific, Cell Penetrating Peptide for Therapeutic Applications in Multiple Sclerosis

Heffernan, C., Sumer, H., Guillemin, G. J., Manuelpillai, U. & Verma, P. J., 25 Sep 2012, In : PLoS ONE. 7, 9, p. 1-12 12 p., e45501.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2015

The kynurenine pathway of tryptophan degradation is activated during osteoblastogenesis

Vidal, C., Li, W., Santner-Nanan, B., Lim, C. K., Guillemin, G. J., Ball, H. J., Hunt, N. H., Nanan, R. & Duque, G., 1 Jan 2015, In : Stem Cells. 33, 1, p. 111-121 11 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2014

Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier

Wilhelm, I., Fazakas, C., Molnár, J., Haskó, J., Végh, A. G., Cervenak, L., Nagyoszi, P., Nyúl-Tóth, Á., Farkas, A. E., Bauer, H., Guillemin, G. J., Bauer, H. C., Váró, G. & Krizbai, I. A., Jan 2014, In : Pigment Cell and Melanoma Research. 27, 1, p. 113-123 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2015

Neuroinflammation in multiple system atrophy: Response to and cause of α-synuclein aggregation

Vieira, B. D. M., Radford, R. A., Chung, R. S., Guillemin, G. J. & Pountney, D. L., 12 Nov 2015, In : Frontiers in Cellular Neuroscience. 9, p. 1-9 9 p., 437.

Research output: Contribution to journalReview article

Open Access
File
38 Citations (Scopus)
33 Downloads (Pure)
2016

Post-Bariatric surgery changes in quinolinic and xanthurenic acid concentrations are associated with glucose homeostasis

Favennec, M., Hennart, B., Verbanck, M., Pigeyre, M., Caiazzo, R., Raverdy, V., Verkindt, H., Leloire, A., Guillemin, G. J., Yengo, L., Allorge, D., Froguel, P., Pattou, F. & Poulain-Godefroy, O., 1 Jun 2016, In : PLoS ONE. 11, 6, p. 1-12 12 p., e0158051.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
20 Downloads (Pure)
2014

Pomegranate and brain health

Daradkeh, G., Essa, M. M., Parvathy, R. K., Subash, S., Al-Adawi, S., Akbar, M., Waly, M. I., Guillemin, G. J. & Brown, A. M., 2014, Food and Brain Health. Essa, M. M., Memon, M. A. & Akbar, M. (eds.). New York: Nova Science Publishers, p. 151-168 18 p. ( Food and Beverage Consumption and Health).

Research output: Chapter in Book/Report/Conference proceedingChapter

2019

Sphingosine kinase 2 potentiates amyloid deposition but protects against hippocampal volume loss and demyelination in a mouse model of Alzheimer's disease

Lei, M., Teo, J. D., Song, H., McEwen, H. P., Yup Lee, J., Couttas, T. A., Duncan, T., Chesworth, R., Bertz, J., Przybyla, M., Van Eersel, J., Heng, B., Guillemin, G. J., Ittner, L. M., Fath, T., Garner, B., Ittner, A., Karl, T. & Don, A. S., 27 Nov 2019, In : The Journal of Neuroscience. 39, 48, p. 9645-9659 15 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Microglia are both a source and target of extracellular cyclophilin A

Flora, G. K., Anderton, R. S., Meloni, B. P., Guillemin, G. J., Knuckey, N. W., MacDougall, G., Matthews, V. & Boulos, S., 1 Sep 2019, In : Heliyon. 5, 9, p. 1-8 8 p., e02390.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)
2016

Influences of chronic mild stress exposure on motor, non-motor impairments and neurochemical variables in specific brain areas of MPTP/probenecid induced neurotoxicity in mice

Janakiraman, U., Manivasagam, T., Thenmozhi, A. J., Essa, M. M., Barathidasan, R., SaravanaBabu, C., Guillemin, G. J. & Khan, M. A. S., 14 Jan 2016, In : PLoS ONE. 11, 1, p. 1-25 25 p., e0146671.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
13 Downloads (Pure)
2012

Omega 3 fatty acids and its potential health benefits

Guizani, N., Essa, M. M., Al-Kharousi, Z., Singh, V., Soussi, B. & Guillemin, G. J., 2012, Natural Products and Their Active Compounds on Disease Prevention. Essa, M. M., Manickavasagan, A. & Sukumar, E. (eds.). New York: Nova Science Publishers, p. 119-122 4 p. (Food science and technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
2015

The next decade in tryptophan metabolism research

Lim, C. K. & Guillemin, G. J., 1 Jan 2015, Targeting the Broadly Pathogenic Kynurenine Pathway. Mittal, S. (ed.). Cham: Springer, Springer Nature, p. 419-425 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration

Ray, S., Howells, C., Eaton, E. D., Butler, C. W., Shabala, L., Adlard, P. A., West, A. K., Bennett, W. R., Guillemin, G. J. & Chung, R. S., 2011, In : PLoS ONE. 6, 4, p. 1-9 9 p., e19026.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
4 Downloads (Pure)
2019

Dendritic spines: revisiting the physiological role

Chidambaram, S. B., Rathipriya, A. G., Bolla, S. R., Bhat, A., Ray, B., Mahalakshmi, A. M., Manivasagam, T., Thenmozhi, A. J., Essa, M. M., Guillemin, G. J., Chandra, R. & Sakharkar, M. K., 8 Jun 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 92, p. 161-193 33 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)
7 Citations (Scopus)
2017

Bcl11b-A critical neurodevelopmental transcription factor-roles in health and disease

Lennon, M. J., Jones, S. P., Lovelace, M. D., Guillemin, G. J. & Brew, B. J., 29 Mar 2017, In : Frontiers in Cellular Neuroscience. 11, p. 1-7 7 p., 89.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
4 Downloads (Pure)

Dietary supplements/antioxidants: impact on redox status in brain diseases

Guillemin, G. J., Essa, M. M., Song, B. J. & Manivasagam, T., 2017, In : Oxidative Medicine and Cellular Longevity. 2017, p. 1-2 2 p., 5048432.

Research output: Contribution to journalEditorial

Open Access
File
5 Citations (Scopus)
7 Downloads (Pure)
2015

Dietary Supplementation of Walnut Partially Reverses 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Induced Neurodegeneration in a Mouse Model of Parkinson’s Disease

Essa, M. M., Subash, S., Dhanalakshmi, C., Manivasagam, T., Al-Adawi, S., Guillemin, G. J. & Thenmozhi, A. J., 15 Jun 2015, In : Neurochemical Research. 40, 6, p. 1283-1293 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2013

Natural products and their benefits on experimental hyperammonemia - a review

Selvaraju, S., Essa, M. M., Waly, M. I., Ali, A., Al-Rawahi, A. S., Vijayan, R. K., Guillemin, G. J., Perumal, S., Manivasagam, T. & Anandhan, A., 2013, Food as medicine. Essa, M. M. & Memon, M. A. (eds.). New York: Nova Science Publishers, p. 353-373 21 p. (Food science and technology).

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

HIV, prospective memory, and cerebrospinal fluid concentrations of quinolinic acid and phosphorylated Tau

Anderson, A. M., Croteau, D., Ellis, R. J., Rosario, D., Potter, M., Guillemin, G. J., Brew, B. J., Woods, S. P. & Letendre, S. L., 15 Jun 2018, In : Journal of Neuroimmunology. 319, p. 13-18 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Telmisartan ameliorates astroglial and dopaminergic functions in a mouse model of chronic Parkinsonism

Sekar, S., Mani, S., Rajamani, B., Manivasagam, T., Thenmozhi, A. J., Bhat, A., Ray, B., Essa, M. M., Guillemin, G. J. & Chidambaram, S. B., Oct 2018, In : Neurotoxicity Research. 34, 3, p. 597-612 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014

Memory deficits and learning skills improved in transgenic mouse model of Alzheimer's disease after date-rich diet supplementation

Subash, S., Essa, M., Awlad-Thani, K., Al-Adawi, S., Al-Asmi, A., Vaishnav, R. & Guillemin, G., Apr 2014, In : FASEB Journal. 28, 1, p. 1-2 2 p.

Research output: Contribution to journalMeeting abstract