A case study of exercise adherence during stereotactic ablative radiotherapy treatment in a previously active male with metastatic renal cell carcinoma

Michael C. Hartland, Kade Davison, Maximillian J. Nelson, Jonathan D. Buckley, Gaynor Parfitt, Joel Fuller

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Stereotactic Ablative Radiotherapy (SABR) is increasingly replacing thoracotomy for resection of lung cancers and oligometastatic lung lesions but it is not known whether exercise can be maintained during SABR, the major side-effect of which is fatigue. This case study describes a 57-year-old male who exercised regularly (above American College of Sports Medicine minimum weekly exercise guidelines) and continued to exercise during SABR for a renal cell metastasis in his left lung. His exercise program included 5x60-minute moderate intensity aerobic exercise sessions and 3x45-minute resistance exercise sessions per week for 12 weeks post-treatment. Cardiorespiratory fitness and strength, as well as self-reported fatigue, depression, anxiety, physical wellbeing and sleep quality were assessed at baseline and fortnightly. Exercise adherence was 98% and no adverse events occurred. Fatigue was elevated from Weeks 2-8, which adversely impacted exercise intensity perception. Minimal changes were observed in cardiorespiratory fitness, depression, anxiety and sleep quality, but strength decreased, and physical wellbeing was improved above baseline levels. This is the first reported clinical case of exercise during SABR for a lung carcinoma. The data suggest that exercise may be feasible for patients undergoing SABR and may improve physical wellbeing. Larger controlled studies are needed to confirm these findings.
LanguageEnglish
Pages462-470
Number of pages9
JournalJournal of Sports Science and Medicine
Volume18
Issue number3
Publication statusPublished - 1 Sep 2019

Fingerprint

Renal Cell Carcinoma
Radiotherapy
Exercise
Fatigue
Therapeutics
Lung Neoplasms
Sleep
Anxiety
Depression
Lung
Thoracotomy
Guidelines
Neoplasm Metastasis
Carcinoma
Kidney

Keywords

  • supportive cancer care
  • aerobic exercise
  • resistance exercise
  • maximal oxygen uptake
  • muscle strength
  • fatigue

Cite this

Hartland, Michael C. ; Davison, Kade ; Nelson, Maximillian J. ; Buckley, Jonathan D. ; Parfitt, Gaynor ; Fuller, Joel. / A case study of exercise adherence during stereotactic ablative radiotherapy treatment in a previously active male with metastatic renal cell carcinoma. In: Journal of Sports Science and Medicine. 2019 ; Vol. 18, No. 3. pp. 462-470.
@article{a6c64f605a124ee4a65bde4edef3450d,
title = "A case study of exercise adherence during stereotactic ablative radiotherapy treatment in a previously active male with metastatic renal cell carcinoma",
abstract = "Stereotactic Ablative Radiotherapy (SABR) is increasingly replacing thoracotomy for resection of lung cancers and oligometastatic lung lesions but it is not known whether exercise can be maintained during SABR, the major side-effect of which is fatigue. This case study describes a 57-year-old male who exercised regularly (above American College of Sports Medicine minimum weekly exercise guidelines) and continued to exercise during SABR for a renal cell metastasis in his left lung. His exercise program included 5x60-minute moderate intensity aerobic exercise sessions and 3x45-minute resistance exercise sessions per week for 12 weeks post-treatment. Cardiorespiratory fitness and strength, as well as self-reported fatigue, depression, anxiety, physical wellbeing and sleep quality were assessed at baseline and fortnightly. Exercise adherence was 98{\%} and no adverse events occurred. Fatigue was elevated from Weeks 2-8, which adversely impacted exercise intensity perception. Minimal changes were observed in cardiorespiratory fitness, depression, anxiety and sleep quality, but strength decreased, and physical wellbeing was improved above baseline levels. This is the first reported clinical case of exercise during SABR for a lung carcinoma. The data suggest that exercise may be feasible for patients undergoing SABR and may improve physical wellbeing. Larger controlled studies are needed to confirm these findings.",
keywords = "supportive cancer care, aerobic exercise, resistance exercise, maximal oxygen uptake, muscle strength, fatigue",
author = "Hartland, {Michael C.} and Kade Davison and Nelson, {Maximillian J.} and Buckley, {Jonathan D.} and Gaynor Parfitt and Joel Fuller",
year = "2019",
month = "9",
day = "1",
language = "English",
volume = "18",
pages = "462--470",
journal = "Journal of Sports Science and Medicine",
issn = "1303-2968",
publisher = "Department of Sports Medicine, Medical Faculty of Uludag University",
number = "3",

}

A case study of exercise adherence during stereotactic ablative radiotherapy treatment in a previously active male with metastatic renal cell carcinoma. / Hartland, Michael C.; Davison, Kade; Nelson, Maximillian J.; Buckley, Jonathan D.; Parfitt, Gaynor; Fuller, Joel.

In: Journal of Sports Science and Medicine, Vol. 18, No. 3, 01.09.2019, p. 462-470.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A case study of exercise adherence during stereotactic ablative radiotherapy treatment in a previously active male with metastatic renal cell carcinoma

AU - Hartland, Michael C.

AU - Davison, Kade

AU - Nelson, Maximillian J.

AU - Buckley, Jonathan D.

AU - Parfitt, Gaynor

AU - Fuller, Joel

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Stereotactic Ablative Radiotherapy (SABR) is increasingly replacing thoracotomy for resection of lung cancers and oligometastatic lung lesions but it is not known whether exercise can be maintained during SABR, the major side-effect of which is fatigue. This case study describes a 57-year-old male who exercised regularly (above American College of Sports Medicine minimum weekly exercise guidelines) and continued to exercise during SABR for a renal cell metastasis in his left lung. His exercise program included 5x60-minute moderate intensity aerobic exercise sessions and 3x45-minute resistance exercise sessions per week for 12 weeks post-treatment. Cardiorespiratory fitness and strength, as well as self-reported fatigue, depression, anxiety, physical wellbeing and sleep quality were assessed at baseline and fortnightly. Exercise adherence was 98% and no adverse events occurred. Fatigue was elevated from Weeks 2-8, which adversely impacted exercise intensity perception. Minimal changes were observed in cardiorespiratory fitness, depression, anxiety and sleep quality, but strength decreased, and physical wellbeing was improved above baseline levels. This is the first reported clinical case of exercise during SABR for a lung carcinoma. The data suggest that exercise may be feasible for patients undergoing SABR and may improve physical wellbeing. Larger controlled studies are needed to confirm these findings.

AB - Stereotactic Ablative Radiotherapy (SABR) is increasingly replacing thoracotomy for resection of lung cancers and oligometastatic lung lesions but it is not known whether exercise can be maintained during SABR, the major side-effect of which is fatigue. This case study describes a 57-year-old male who exercised regularly (above American College of Sports Medicine minimum weekly exercise guidelines) and continued to exercise during SABR for a renal cell metastasis in his left lung. His exercise program included 5x60-minute moderate intensity aerobic exercise sessions and 3x45-minute resistance exercise sessions per week for 12 weeks post-treatment. Cardiorespiratory fitness and strength, as well as self-reported fatigue, depression, anxiety, physical wellbeing and sleep quality were assessed at baseline and fortnightly. Exercise adherence was 98% and no adverse events occurred. Fatigue was elevated from Weeks 2-8, which adversely impacted exercise intensity perception. Minimal changes were observed in cardiorespiratory fitness, depression, anxiety and sleep quality, but strength decreased, and physical wellbeing was improved above baseline levels. This is the first reported clinical case of exercise during SABR for a lung carcinoma. The data suggest that exercise may be feasible for patients undergoing SABR and may improve physical wellbeing. Larger controlled studies are needed to confirm these findings.

KW - supportive cancer care

KW - aerobic exercise

KW - resistance exercise

KW - maximal oxygen uptake

KW - muscle strength

KW - fatigue

M3 - Article

VL - 18

SP - 462

EP - 470

JO - Journal of Sports Science and Medicine

T2 - Journal of Sports Science and Medicine

JF - Journal of Sports Science and Medicine

SN - 1303-2968

IS - 3

ER -