A comparison of the hemodynamic effects of flow diverters on wide-necked and narrow-necked cerebral aneurysms

Yong Fa Wu, Peng Fei Yang, Jie Shen, Qing Hai Huang, Xing Zhang, Yi Qian, Jian Min Liu*

*Corresponding author for this work

    Research output: Contribution to journalArticle

    12 Citations (Scopus)


    Flow diverters (FD), a new generation of intracranial stents with a low porosity mesh, have been applied as an alternative treatment for intracranial aneurysms. However, their efficacy varies among aneurysms of different morphology. In this study, computational fluid dynamic simulations were performed to examine the influence of an FD on the hemodynamics of wide-necked and narrow-necked cerebral aneurysms. An FD with 70% porosity mesh was deployed across the neck of an ideal narrow-necked and wide-neck aneurysm model. The hemodynamics at the aneurysmal sac were changed markedly in both models. At the inflow portion of the aneurysm neck of the narrow-necked aneurysm, the peak velocity and wall shear stress were reduced by 84% and 91%, respectively. By comparison, in the wide-necked aneurysm model, the results were 47% and 21%, respectively. This study demonstrates that the FD markedly altered the hemodynamic conditions inside intracranial aneurysms, depending on aneurysm morphology. Therefore, hemodynamic modifications should be individually designed for aneurysms with different morphology.

    Original languageEnglish
    Pages (from-to)1520-1524
    Number of pages5
    JournalJournal of Clinical Neuroscience
    Issue number11
    Publication statusPublished - Nov 2012


    Cite this