A computerized scanner to quantify atherosclerosis

M. J. Legg, B. S. Gow, M. Hodgekiss

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A method is described for the quantitation of atherosclerotic lesion after excision and staining of the vessel. Essentially the device consists of a microscope with a computer-controlled stage which moves a photographic negative image over a square beam (0.1 mm sides) of light. At each translation-step of the stage a transmittance reading is taken using a photomultiplier tube for detection. The computer stores topographical values (typically around 6,000) and, by setting a threshold, can determine the fractional area of artery which is diseased.

Original languageEnglish
Pages (from-to)505-514
Number of pages10
Issue number4
Publication statusPublished - 1980
Externally publishedYes


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