A couple with gastrointestinal stromal tumor (GIST)

Pirooz Poursoltan*, Stephen Begbie

*Corresponding author for this work

Research output: Contribution to journalLetter

Abstract

We present a 70-year old woman with metastatic gastrointestinal stromal tumor (GIST) and her partner, a 79-year old man with multiple gastric GIST tumors. This tumor is considered a rare malignancy with a reported incidence of 6-13 new cases per million. Our patients were found to have different genetic mutations in the C-KIT gene as the cause of their disease but, given the rarity of this tumor, it raises a question about their possible exposure to carcinogens or another shared mechanism that might have been involved in the pathogenesis of this cancer.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalAsia-Pacific Journal of Clinical Oncology
Volume5
Issue number2
DOIs
Publication statusPublished - Jun 2009
Externally publishedYes

Keywords

  • TYROSINE KINASE
  • PHASE-I
  • IMATINIB
  • KIT
  • MUTATION

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