TY - JOUR
T1 - A glycosylated proteolipid protein is common to CNS myelin of recent lungfish (Ceratodiae, Lepidosirenidae)
AU - Waehneldt, T. V.
AU - Matthieu, J. M.
AU - Malotka, J.
AU - Joss, J.
PY - 1987
Y1 - 1987
N2 - 1. 1. Myelin proteins from the CNS of recent lungfish (Lepidosiren paradoxa, Protopterus dolloi, Neoceratodus forsteri) were separated and analysed by staining and immunoblotting. 2. 2. All species showed a glycosylated component (g-PLP) that cross-reacted with antibodies against tetrapod proteolipid protein (PLP), indicating phylogenetic relationships with amphibia. 3. 3. Actinopterygian IP or teleostean 36 k components were not detectable in lungfish CNS myelin. 4. 4. The identical size of g-PLPs from Lepidosiren and Protopterus (Mr = 29,000) underlines the close relationship of the Lepidosirenidae. The smaller size of g-PLP from the ceratodidan Neoceratodus forsteri (Mr = 27,500) pointed to an earlier diversion.
AB - 1. 1. Myelin proteins from the CNS of recent lungfish (Lepidosiren paradoxa, Protopterus dolloi, Neoceratodus forsteri) were separated and analysed by staining and immunoblotting. 2. 2. All species showed a glycosylated component (g-PLP) that cross-reacted with antibodies against tetrapod proteolipid protein (PLP), indicating phylogenetic relationships with amphibia. 3. 3. Actinopterygian IP or teleostean 36 k components were not detectable in lungfish CNS myelin. 4. 4. The identical size of g-PLPs from Lepidosiren and Protopterus (Mr = 29,000) underlines the close relationship of the Lepidosirenidae. The smaller size of g-PLP from the ceratodidan Neoceratodus forsteri (Mr = 27,500) pointed to an earlier diversion.
UR - http://www.scopus.com/inward/record.url?scp=0023461728&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(87)90025-3
DO - 10.1016/0305-0491(87)90025-3
M3 - Article
C2 - 2448081
AN - SCOPUS:0023461728
VL - 88
SP - 1209
EP - 1212
JO - Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology
JF - Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology
SN - 1096-4959
IS - 4
ER -