Abstract
We describe the first highly polymorphic microsatellite marker for the human urokinase plasminogen activator receptor gene (PLAUR). The urokinase receptor (uPAR) has a central role in cancer invasion and metastasis, which may enable the development of new anti-metastatic therapies. Analysis of the marker genotypes in colorectal cancer cell lines revealed three alleles that were not detected in a series of healthy control individuals, which encourages further genetic study of the role of uPAR in cancer.
Original language | English |
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Pages (from-to) | 124-125 |
Number of pages | 2 |
Journal | Human Genetics |
Volume | 97 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 1996 |
Externally published | Yes |