A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR)

Maija R. J. Kohonen-Corish; Yao Wang; William F. Doe

doi:10.1007/BF00218847

A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR)

Maija R. J. Kohonen-Corish^*, Yao Wang, William F. Doe

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

We describe the first highly polymorphic microsatellite marker for the human urokinase plasminogen activator receptor gene (PLAUR). The urokinase receptor (uPAR) has a central role in cancer invasion and metastasis, which may enable the development of new anti-metastatic therapies. Analysis of the marker genotypes in colorectal cancer cell lines revealed three alleles that were not detected in a series of healthy control individuals, which encourages further genetic study of the role of uPAR in cancer.

Original language	English
Pages (from-to)	124-125
Number of pages	2
Journal	Human Genetics
Volume	97
Issue number	1
DOIs	https://doi.org/10.1007/BF00218847
Publication status	Published - Jan 1996
Externally published	Yes

Access to Document

10.1007/BF00218847

Cite this

@article{b3b4997df1354aad852d636210f02ce7,

title = "A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR)",

abstract = "We describe the first highly polymorphic microsatellite marker for the human urokinase plasminogen activator receptor gene (PLAUR). The urokinase receptor (uPAR) has a central role in cancer invasion and metastasis, which may enable the development of new anti-metastatic therapies. Analysis of the marker genotypes in colorectal cancer cell lines revealed three alleles that were not detected in a series of healthy control individuals, which encourages further genetic study of the role of uPAR in cancer.",

author = "Kohonen-Corish, \{Maija R. J.\} and Yao Wang and Doe, \{William F.\}",

year = "1996",

month = jan,

doi = "10.1007/BF00218847",

language = "English",

volume = "97",

pages = "124--125",

journal = "Human Genetics",

issn = "0340-6717",

publisher = "Springer, Springer Nature",

number = "1",

}

TY - JOUR

T1 - A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR)

AU - Kohonen-Corish, Maija R. J.

AU - Wang, Yao

AU - Doe, William F.

PY - 1996/1

Y1 - 1996/1

N2 - We describe the first highly polymorphic microsatellite marker for the human urokinase plasminogen activator receptor gene (PLAUR). The urokinase receptor (uPAR) has a central role in cancer invasion and metastasis, which may enable the development of new anti-metastatic therapies. Analysis of the marker genotypes in colorectal cancer cell lines revealed three alleles that were not detected in a series of healthy control individuals, which encourages further genetic study of the role of uPAR in cancer.

AB - We describe the first highly polymorphic microsatellite marker for the human urokinase plasminogen activator receptor gene (PLAUR). The urokinase receptor (uPAR) has a central role in cancer invasion and metastasis, which may enable the development of new anti-metastatic therapies. Analysis of the marker genotypes in colorectal cancer cell lines revealed three alleles that were not detected in a series of healthy control individuals, which encourages further genetic study of the role of uPAR in cancer.

UR - https://www.scopus.com/pages/publications/0030050098

U2 - 10.1007/BF00218847

DO - 10.1007/BF00218847

M3 - Article

C2 - 8557253

AN - SCOPUS:0030050098

SN - 0340-6717

VL - 97

SP - 124

EP - 125

JO - Human Genetics

JF - Human Genetics

IS - 1

ER -

A highly polymorphic CA/GT repeat in intron 3 of the human urokinase receptor gene (PLAUR)

Abstract

Access to Document

Other files and links

Fingerprint

Cite this