TY - JOUR
T1 - A meta-analysis of minimally invasive versus conventional sternotomy for aortic valve replacement
AU - Phan, Kevin
AU - Xie, Ashleigh
AU - Di Eusanio, Marco
AU - Yan, Tristan D.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Minimally invasive aortic valve replacement (AVR) is increasingly used as an alternative to conventional AVR, despite limited randomized evidence available. To assess the evidence base, a systematic search identified 50 comparative studies with a total of 12,786 patients. A meta-analysis demonstrated that minimally invasive AVR is associated with reduced transfusion incidence, intensive care stay, hospitalization, and renal failure, and has a mortality rate that is comparable to conventional AVR. The evidence quality was mostly very low. Given the inadequate statistical power and heterogeneity of available studies, prospective randomized trials are needed to assess the benefits and risks of minimally invasive AVR approaches.
AB - Minimally invasive aortic valve replacement (AVR) is increasingly used as an alternative to conventional AVR, despite limited randomized evidence available. To assess the evidence base, a systematic search identified 50 comparative studies with a total of 12,786 patients. A meta-analysis demonstrated that minimally invasive AVR is associated with reduced transfusion incidence, intensive care stay, hospitalization, and renal failure, and has a mortality rate that is comparable to conventional AVR. The evidence quality was mostly very low. Given the inadequate statistical power and heterogeneity of available studies, prospective randomized trials are needed to assess the benefits and risks of minimally invasive AVR approaches.
UR - http://www.scopus.com/inward/record.url?scp=84908116834&partnerID=8YFLogxK
U2 - 10.1016/j.athoracsur.2014.05.060
DO - 10.1016/j.athoracsur.2014.05.060
M3 - Review article
C2 - 25064516
AN - SCOPUS:84908116834
SN - 0003-4975
VL - 98
SP - 1499
EP - 1511
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 4
ER -